Category:GO:0004707 ! MAP kinase activity

name: MAP kinase activity
namespace: molecular_function
alt_id: GO:0008338
alt_id: GO:0008339
alt_id: GO:0016908
alt_id: GO:0016909
def: "Catalysis of the reaction: protein + ATP = protein phosphate + ADP. This reaction is the phosphorylation of proteins. Mitogen-activated protein kinase; a family of protein kinases that perform a crucial step in relaying signals from the plasma membrane to the nucleus. They are activated by a wide range of proliferation- or differentiation-inducing signals; activation is strong with agonists such as polypeptide growth factors and tumor-promoting phorbol esters, but weak (in most cell backgrounds) by stress stimuli." [GOC:ma, ISBN:0198547684]
synonym: "ATP:protein phosphotransferase (MAPKK-activated) activity" RELATED [EC:2.7.11.24]
synonym: "ERK" RELATED [EC:2.7.11.24]
synonym: "ERK1" EXACT []
synonym: "ERK2" RELATED []
synonym: "extracellular signal-regulated kinase activity" NARROW [EC:2.7.11.24]
synonym: "MAP kinase 1 activity" NARROW []
synonym: "MAP kinase 2 activity" NARROW []
synonym: "MAPK" RELATED [EC:2.7.11.24, PMID:20811974]
synonym: "MBP kinase I activity" NARROW [EC:2.7.11.24]
synonym: "MBP kinase II activity" NARROW [EC:2.7.11.24]
synonym: "mitogen activated kinase activity" EXACT []
synonym: "mitogen-activated protein kinase activity" RELATED [EC:2.7.11.24]
synonym: "myelin basic protein kinase activity" NARROW [EC:2.7.11.24]
synonym: "SAP kinase activity" NARROW []
synonym: "SAPK" NARROW []
synonym: "stress-activated kinase activity" NARROW []
synonym: "stress-activated protein kinase activity" NARROW []
xref: EC:2.7.11.24
xref: KEGG_REACTION:R00162
xref: MetaCyc:2.7.11.24-RXN
is_a: GO:0004674 ! protein serine/threonine kinase activity
relationship: part_of: GO:0000165 ! MAPK cascade

AmiGO <GOterm>GO:0004707</GOterm>
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