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CHICK:MK06

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Species (Taxon ID) Gallus gallus (Chicken). (9031)
Gene Name(s) MAPK6
Protein Name(s) Mitogen-activated protein kinase 6

MAP kinase 6 MAPK 6

External Links
UniProt Q5F3W3
EMBL AJ851537
RefSeq NP_001025720.1
UniGene Gga.3411
ProteinModelPortal Q5F3W3
SMR Q5F3W3
STRING 9031.ENSGALP00000007460
PaxDb Q5F3W3
Ensembl ENSGALT00000007472
GeneID 415419
KEGG gga:415419
CTD 5597
eggNOG COG0515
GeneTree ENSGT00550000074298
HOGENOM HOG000233020
HOVERGEN HBG104376
InParanoid Q5F3W3
KO K06855
OMA EHDWPIH
OrthoDB EOG780RKS
PhylomeDB Q5F3W3
TreeFam TF105098
NextBio 20819031
PRO PR:Q5F3W3
Proteomes UP000000539
ExpressionAtlas Q5F3W3
GO GO:0005524
GO:0004707
GO:0007049
InterPro IPR011009
IPR008350
IPR000719
IPR017441
IPR002290
IPR008271
Pfam PF00069
PRINTS PR01771
SMART SM00220
SUPFAM SSF56112
PROSITE PS00107
PS50011
PS00108

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0071310

cellular response to organic substance

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001172432
RGD:70500

P

Seeded From UniProt

complete

involved_in

GO:0035556

intracellular signal transduction

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:106908
MGI:MGI:1201387
MGI:MGI:1201408
MGI:MGI:1346865
PANTHER:PTN000622075
RGD:3046
RGD:70500
RGD:71050
UniProtKB:P78362
UniProtKB:Q16539
UniProtKB:Q96SB4
UniProtKB:Q9UPZ9
WB:WBGene00004055
WB:WBGene00004056

P

Seeded From UniProt

complete

involved_in

GO:0010468

regulation of gene expression

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1346861
PANTHER:PTN000622075
UniProtKB:A9T142

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0052703
FB:FBgn0267339
MGI:MGI:1201408
MGI:MGI:1346347
MGI:MGI:1346858
MGI:MGI:1346859
MGI:MGI:1346861
MGI:MGI:1346862
MGI:MGI:1346863
MGI:MGI:1346865
MGI:MGI:1354946
MGI:MGI:2444559
PANTHER:PTN000622075
PomBase:SPAC24B11.06c
PomBase:SPBC119.08
PomBase:SPBC530.14c
RGD:3046
RGD:621506
RGD:628847
RGD:70500
RGD:70975
RGD:71050
SGD:S000000112
SGD:S000004103
SGD:S000004829
TAIR:locus:2024887
TAIR:locus:2124943
UniProtKB:A9T142
UniProtKB:O77306
UniProtKB:P28482
UniProtKB:P78362
UniProtKB:Q10N20
UniProtKB:Q13164
UniProtKB:Q96SB4
WB:WBGene00002178
WB:WBGene00002187
WB:WBGene00003048
WB:WBGene00003401
WB:WBGene00004056
WB:WBGene00004057

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0003256
FB:FBgn0015765
MGI:MGI:1201387
MGI:MGI:1201408
MGI:MGI:1336881
MGI:MGI:1346347
MGI:MGI:1346858
MGI:MGI:1346859
MGI:MGI:1346861
MGI:MGI:1346865
MGI:MGI:1354946
MGI:MGI:1934157
MGI:MGI:2444559
MGI:MGI:96913
PANTHER:PTN000622075
PomBase:SPAC24B11.06c
PomBase:SPAC31G5.09c
PomBase:SPBC119.08
PomBase:SPBC530.14c
RGD:3046
RGD:3663
RGD:621505
RGD:621506
RGD:628675
RGD:628847
RGD:70496
RGD:70500
SGD:S000000112
SGD:S000001072
SGD:S000003272
SGD:S000003642
SGD:S000004103
TAIR:locus:2024887
TAIR:locus:2124943
UniProtKB:A9T142
UniProtKB:O77306
UniProtKB:P20794
UniProtKB:P28482
UniProtKB:P45983
UniProtKB:P78362
UniProtKB:Q10N20
UniProtKB:Q13164
UniProtKB:Q5AZN7
UniProtKB:Q8GYQ5
UniProtKB:Q96SB4
UniProtKB:Q9LV37
UniProtKB:Q9P419
WB:WBGene00002178
WB:WBGene00003048
WB:WBGene00003401
WB:WBGene00004055
WB:WBGene00004057
dictyBase:DDB_G0283903
dictyBase:DDB_G0286353

C

Seeded From UniProt

complete

enables

GO:0004707

MAP kinase activity

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0015765
FB:FBgn0024846
FB:FBgn0267339
MGI:MGI:1346858
MGI:MGI:1346859
MGI:MGI:1346865
MGI:MGI:1354946
PANTHER:PTN001172432
PomBase:SPAC31G5.09c
PomBase:SPBC119.08
RGD:1309340
RGD:3045
RGD:3046
RGD:621505
RGD:70496
RGD:70500
RGD:70975
SGD:S000000112
SGD:S000003272
SGD:S000006258
UniProtKB:A0A1D8PFT5
UniProtKB:A0A1D8PT38
UniProtKB:O15264
UniProtKB:P27361
UniProtKB:Q15759
UniProtKB:Q16539
WB:WBGene00003401
WB:WBGene00004055
WB:WBGene00004056
dictyBase:DDB_G0286353

F

Seeded From UniProt

complete

enables

GO:0004707

MAP kinase activity

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

CGD:CAL0000183747
FB:FBgn0015765
FB:FBgn0024846
FB:FBgn0267339
MGI:MGI:1346858
MGI:MGI:1346859
MGI:MGI:1346865
MGI:MGI:1354946
PANTHER:PTN002372889
PomBase:SPAC31G5.09c
PomBase:SPBC119.08
RGD:1309340
RGD:3045
RGD:3046
RGD:621505
RGD:70496
RGD:70500
RGD:70975
SGD:S000000112
SGD:S000003272
SGD:S000006258
UniProtKB:A0A1D8PFT5
UniProtKB:A0A1D8PT38
UniProtKB:O15264
UniProtKB:P27361
UniProtKB:Q15759
UniProtKB:Q16539
WB:WBGene00003401
WB:WBGene00004055
WB:WBGene00004056
dictyBase:DDB_G0286353

F

Seeded From UniProt

complete

involved_in

GO:0000165

MAPK cascade

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0004707

P

Seeded From UniProt

complete

involved_in

GO:0000165

MAPK cascade

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0004707

P

Seeded From UniProt

complete

involved_in

GO:0000165

MAPK cascade

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0004707

P

Seeded From UniProt

complete

involved_in

GO:0000165

MAPK cascade

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0004707

P

Seeded From UniProt

complete

involved_in

GO:0000165

MAPK cascade

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0004707

P

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q16659
ensembl:ENSP00000261845

C

Seeded From UniProt

complete

involved_in

GO:0060999

positive regulation of dendritic spine development

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q61532
ensembl:ENSMUSP00000129024

P

Seeded From UniProt

complete

enables

GO:0046982

protein heterodimerization activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q61532
ensembl:ENSMUSP00000129024

F

Seeded From UniProt

complete

part_of

GO:0032991

protein-containing complex

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q61532
ensembl:ENSMUSP00000129024

C

Seeded From UniProt

complete

part_of

GO:0032156

septin cytoskeleton

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q61532
ensembl:ENSMUSP00000129024

C

Seeded From UniProt

complete

enables

GO:0019901

protein kinase binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q61532
ensembl:ENSMUSP00000129024

F

Seeded From UniProt

complete

involved_in

GO:0006468

protein phosphorylation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q61532
ensembl:ENSMUSP00000129024

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q61532
ensembl:ENSMUSP00000129024

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q61532
ensembl:ENSMUSP00000129024

C

Seeded From UniProt

complete

enables

GO:0004707

MAP kinase activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q61532
ensembl:ENSMUSP00000129024

F

Seeded From UniProt

complete

enables

GO:0004672

protein kinase activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q61532
ensembl:ENSMUSP00000129024

F

Seeded From UniProt

complete

enables

GO:0004672

protein kinase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000719
InterPro:IPR008271

F

Seeded From UniProt

complete

enables

GO:0004707

MAP kinase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR008350

F

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000719
InterPro:IPR008350
InterPro:IPR017441

F

Seeded From UniProt

complete

involved_in

GO:0006468

protein phosphorylation

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000719
InterPro:IPR008271
InterPro:IPR008350

P

Seeded From UniProt

complete

enables

GO:0004707

MAP kinase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:2.7.11.24

F

Seeded From UniProt

complete

enables

GO:0016301

kinase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0418

F

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0067

F

Seeded From UniProt

complete

enables

GO:0000166

nucleotide binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0547

F

Seeded From UniProt

complete

involved_in

GO:0016310

phosphorylation

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0418

P

Seeded From UniProt

complete

enables

GO:0016740

transferase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0808

F

Seeded From UniProt

complete

involved_in

GO:0007049

cell cycle

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0131

P

Seeded From UniProt

complete

enables

GO:0004674

protein serine/threonine kinase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0723

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page