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GIAIN:Q8IS81

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Species (Taxon ID) Giardia intestinalis (Giardia lamblia). (5741)
Gene Name(s) ERK2 (ECO:0000313 with EMBL:AAN73430.1)
Protein Name(s) Mitogen-activated protein kinase (ECO:0000256 with RuleBase:RU361165, ECO:0000256 with SAAS:SAAS00095919)
External Links
UniProt Q8IS81
EMBL AY149275
ProteinModelPortal Q8IS81
GO GO:0005524
GO:0004707
InterPro IPR011009
IPR003527
IPR000719
IPR017441
IPR002290
IPR008271
Pfam PF00069
SMART SM00220
SUPFAM SSF56112
PROSITE PS01351
PS00107
PS50011
PS00108

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0005929

cilium

PMID:12397063[1]

ECO:0000314

C

Immunofluorescence analysis was used to identify the location of the protein. Figure 7

complete
CACAO 10747

GO:0005634

nucleus

PMID:12397063[1]

ECO:0000314

C

Immunofluorescence analysis of was used to identify the location of the protein. Figure 7

complete
CACAO 10748

part_of

GO:0005634

nucleus

PMID:12397063[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005929

cilium

PMID:12397063[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0000165

MAPK cascade

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0004707

P

Seeded From UniProt

complete

involved_in

GO:0000165

MAPK cascade

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0004707

P

Seeded From UniProt

complete

enables

GO:0004672

protein kinase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000719
InterPro:IPR008271

F

Seeded From UniProt

complete

enables

GO:0004707

MAP kinase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR003527

F

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000719
InterPro:IPR003527
InterPro:IPR017441

F

Seeded From UniProt

complete

involved_in

GO:0006468

protein phosphorylation

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000719
InterPro:IPR003527
InterPro:IPR008271

P

Seeded From UniProt

complete

enables

GO:0004707

MAP kinase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:2.7.11.24

F

Seeded From UniProt

complete

enables

GO:0000166

nucleotide binding

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0547

F

Seeded From UniProt

complete

enables

GO:0016301

kinase activity

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0418

F

Seeded From UniProt

complete

enables

GO:0004674

protein serine/threonine kinase activity

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0723

F

Seeded From UniProt

complete

involved_in

GO:0016310

phosphorylation

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0418

P

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0067

F

Seeded From UniProt

complete

enables

GO:0016740

transferase activity

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0808

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 Ellis, JG 4th et al. (2003) Potential involvement of extracellular signal-regulated kinase 1 and 2 in encystation of a primitive eukaryote, Giardia lamblia. Stage-specific activation and intracellular localization. J. Biol. Chem. 278 1936-45 PubMed GONUTS page