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User:Wiestcar

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CACAO Spring 2014

My Annotations

StatusPageDate/TimeGO Term (Aspect)ReferenceEvidenceNotesLinks
unacceptableYEASO:E7NHF22014-04-01 11:47:30 CDTGO:0032007 negative regulation of TOR signaling (P)PMID:20530756ECO:0000315 mutant phenotype evidence used in manual assertion

Figure 4B shows that when Saccharomyces cerevisiae loses the gene Ncs6p, it loses the ability to grow when grown with rapamycin.

challenge
unacceptableARATH:F4IU182014-04-01 12:04:11 CDTGO:0032006 regulation of TOR signaling (Figure 4 shows that when Ncs6p is removed, there is no growth in the presence of rapamycin but when rol5 is added, growth begins again.)PMID:20530756IMP: Inferred from Mutant Phenotype
challenge
unacceptableARATH:FUT62014-04-01 13:32:19 CDTGO:0036065 fucosylation (P)PMID:24127514ECO:0000315 mutant phenotype evidence used in manual assertion

Figure 5 shows that when fut6 is removed from the plant, the root cells do not grow as long as wild type when grown in the presence of NaCl

challenge
unacceptableARATH:B3GT12014-04-01 18:47:46 CDTGO:0080022 primary root development (P)PMID:23527103ECO:0000315 mutant phenotype evidence used in manual assertion

Figure 4 shows that when A. thaliana is grown as a mutant with GalT1, there is an increase in primary root length than wild type. It also appears to have more bio mass.

challenge
unacceptableARATH:B3GT12014-04-01 19:02:11 CDTGO:0015995 chlorophyll biosynthetic process (P)PMID:23527103ECO:0000314 direct assay evidence used in manual assertion

Figure 5 shows higher chlorophyll content at different wavelengths when A. thaliana is grown with over expression of GalT1.

challenge
unacceptableARATH:B3GT12014-04-02 17:10:19 CDTGO:0045489 pectin biosynthetic process (P)PMID:23527103ECO:0000315 mutant phenotype evidence used in manual assertion

Figure 10 shows that in the over-expression of GalT1 in A. thaliana, there is an up-regulation of other proteins responsible for the production of pectin.

challenge
unacceptableVERFO:D2XRB62014-04-02 21:16:44 CDTGO:0048316 seed development (P)PMID:24516650ECO:0000314 direct assay evidence used in manual assertion

Figure 4 shows that as the weeks go by of seed development, the levels of OLE1 increases drastically in V. fordii compared to other proteins.

challenge

acceptable:0
unacceptable:7
requires_changes:0
flagged:0

Annotations challenged by Wiestcar

StatusAuthor,GroupPageGO Term (Aspect)ReferenceEvidenceLinksPage history
updatedbyinstructorNathanTFix,
Team Designer Genes
HUMAN:HIF1AGO:0005634 - nucleus (C)PMID:22848707ECO:0000314 direct assay evidence used in manual assertionchallengeC: 1
updatedbyinstructorBmanieri,
Team Chicken Day
HUMAN:COGA1GO:0033622 - integrin activation (P)PMID:16754661ECO:0000314 direct assay evidence used in manual assertionchallengeC: 2
requireschangesJohn.p.schmidt,
The A Team
BIFAP:K4IP48GO:0004616 - phosphogluconate dehydrogenase (decarboxylating) activity (F)PMID:9931298ECO:0000314 direct assay evidence used in manual assertionchallengeC: 2
unacceptableFclingen,
Team What the Fox Says
HUMAN:BRD4GO:0008284 - positive regulation of cell population proliferation (P)PMID:24403256ECO:0000314 direct assay evidence used in manual assertionchallengeC: 1
updatedbyinstructorMin.lorna,
Team Ood
PSEAE:BEKASGO:0042758 - long-chain fatty acid catabolic process (P)PMID:22753057ECO:0000315 mutant phenotype evidence used in manual assertionchallengeC: 1
unacceptableAsigurdsson,
Team On a Boat
RAT:ASIC2GO:0005261 - monoatomic cation channel activity (F)PMID:8631835ECO:0000266 sequence orthology evidence used in manual assertionchallengeC: 3
unacceptableGrolfe,
Team Pancakes At Nite
HUMAN:CIB1GO:0005515 - protein binding (F)PMID:20473878ECO:0000314 direct assay evidence used in manual assertionchallengeC: 2
updatedbyinstructorGrolfe,
Team Pancakes At Nite
HUMAN:PLS1GO:0005730 - nucleolus (C)PMID:24356419ECO:0000314 direct assay evidence used in manual assertionchallengeC: 2

0 annotations fixed by Wiestcar

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