GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.

Have any questions? Please email us at ecoliwiki@gmail.com

Category:Team Chicken Day

From GONUTS
Jump to: navigation, search
StatusPageUserDate/TimeGO Term (Aspect)ReferenceEvidenceNotesLinks
unacceptableHUMAN:RBL1Deasterling, Team Chicken Day2014-02-02 17:27:19 CSTGO:0006611 protein export from nucleus (P)PMID:24302570ECO:0000314 direct assay evidence used in manual assertion

Figure 1:Phosphorylation of retinoblastoma proteins by up-regulation of cyclin-dependent kinase 4 triggers its cytoplasmic translocation from the nucleus in human skeletal muscle myotubes.

challenge
unacceptableHUMAN:COR1BDeasterling, Team Chicken Day2014-02-02 09:57:03 CSTGO:0035767 endothelial cell chemotaxis (P)PMID:23667561ECO:0000314 direct assay evidence used in manual assertion

Rac1 plays a role in S1P-induced redistribution of coronin 1B and cortactin to cell periphery as well as chemotaxis of human pulmonary artery endothelial cells. (Figure 7)

challenge
updatedbyinstructorHUMAN:COR1BDeasterling, Team Chicken Day2014-02-02 09:19:06 CSTGO:0035767 endothelial cell chemotaxis (P)PMID:23667561ECO:0000315 mutant phenotype evidence used in manual assertion

Fig 5

challenge
unacceptableHUMAN:CO3A1Deasterling, Team Chicken Day2014-01-30 11:02:39 CSTGO:0032966 negative regulation of collagen biosynthetic process (P)PMID:24288677ECO:0000314 direct assay evidence used in manual assertion

Figure 4 displays a western blot assay showing collagen III expression in untreated control fibroblasts and control fibroblasts treated with TGF-β1. With TGF-β1 treatment, there was also decreased collagen III expression in transfected fibroblasts. This shows that the inhibitory effect of nAG is dominant over the TGF-β1 effect.

challenge
updatedbyinstructorHUMAN:COGA1Bmanieri, Team Chicken Day2014-01-30 10:59:38 CSTGO:0033627 cell adhesion mediated by integrin (P)PMID:16754661ECO:0000314 direct assay evidence used in manual assertion

Figure 2 depicts (via cell adhesion absorbance) cell attachment to collagen XVI and its inhibition by monoclonal antibodies against α1 and α2 integrin subunits.

challenge
updatedbyinstructorHUMAN:COGA1Bmanieri, Team Chicken Day2014-01-30 10:51:37 CSTGO:0033622 integrin activation (P)PMID:16754661ECO:0000314 direct assay evidence used in manual assertion

Figure 3 depicts via fluorescence tagging that collagen XVI induces recruitment of integrins α1β1 and α2β1 into focal adhesion plaques.

challenge
updatedbyinstructorHUMAN:MFAP2Deasterling, Team Chicken Day2014-01-30 10:36:58 CSTGO:0001527 microfibril (C)PMID:24353434ECO:0000314 direct assay evidence used in manual assertion

Figure 3

challenge
unacceptableHUMAN:CFADBmanieri, Team Chicken Day2014-01-30 10:33:39 CSTGO:0003817 complement factor D activity (F)PMID:00746ECO:0000314 direct assay evidence used in manual assertion

Figure 5 depects that overall, the tertiary structure of the S94Y/T214S/S215W mutant is very similar to that of native factor D.

challenge
unacceptableMOUSE:EGFLABmanieri, Team Chicken Day2014-01-30 10:17:03 CSTGO:0031012 extracellular matrix (C)PMID:16141072ECO:0000314 direct assay evidence used in manual assertion

Figure 2B Shows strong evidence via tag mapping of 3′ end initiation was correlated with a short intergenic distance when in tail-to-tail orientation with a neighboring gene suggesting a possible role in an intergenic regulatory interaction.

challenge
unacceptableHUMAN:ELNDeasterling, Team Chicken Day2014-01-30 10:13:54 CSTGO:0060311 negative regulation of elastin catabolic process (P)PMID:24358135ECO:0000314 direct assay evidence used in manual assertion

Figure 9 shows where the boundaries of the elastic lamellae layers are compromised and loose amorphous elastin has been exposed as a result of elastase digestion.

challenge
unacceptableYEAST:TAF14Bmanieri, Team Chicken Day2014-01-30 10:05:52 CSTGO:0005674 transcription factor TFIIF complex (C)PMID:7995524ECO:0000314 direct assay evidence used in manual assertion

Figure 5 Depicts region 4.2 showing the sequence homology between Tfg2 of bacterial cr factors. Alignment of the carboxy-terminal residues of Tfg2 with the carboxy-terminal residues of E. coli and Bacillus subtilis.

challenge
unacceptableYEAST:TAF14Bmanieri, Team Chicken Day2014-01-30 09:47:34 CSTGO:0005667 transcription factor complex (C)PMID:7995524ECO:0000314 direct assay evidence used in manual assertion

Figure 4E shows the precipitates that were electrophoresed in a SDS-10% poly- acrylamide gel. It shows by the overlap that yeast TAFs can be immunoprecipitated by antibodies against

Tfg3. Antibody against Tfg3 (lane 1) or mAb 12CA5 (lane 2) was used to immunoprecipitate yeast TAFs from a complex fraction.

challenge
unacceptableHUMAN:CO3A1Deasterling, Team Chicken Day2014-01-30 09:14:55 CSTGO:0032966 negative regulation of collagen biosynthetic process (P)PMID:24288677ECO:0000314 direct assay evidence used in manual assertion

Figure 5 depicts through immunofluorescence, nAG protein expression in human fibroblast cells has an inhibitory effect on the expression of collagen I and III.

challenge
updatedbyinstructorHUMAN:COGA1Deasterling, Team Chicken Day2014-01-30 07:35:05 CSTGO:0051894 positive regulation of focal adhesion assembly (P)PMID:24466237ECO:0000314 direct assay evidence used in manual assertion

Figure 2A displays that over expression of Collagen XVI increases interaction with integrin-linked kinase/kindlin-1 only at the focal adhesions.

challenge
unacceptableHUMAN:COGA1Bmanieri, Team Chicken Day2014-01-29 20:20:15 CSTGO:0008544 epidermis development (P)PMID:16754661ECO:0000314 direct assay evidence used in manual assertion

Epidermis

challenge

What do the icons mean in the status column?

assessment icons.jpg

Pages in category "Team Chicken Day"

The following 2 pages are in this category, out of 2 total.


Jump to pages starting with: B D