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MOUSE:EGFLA

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Species (Taxon ID) Mus musculus (Mouse). (10090)
Gene Name(s) Egflam
Protein Name(s) Pikachurin

EGF-like, fibronectin type-III and laminin G-like domain-containing protein Nectican

External Links
UniProt Q4VBE4
EMBL DQ223720
AK031136
AK033332
AK037223
AK041546
AC105969
AC158747
BC051455
BC095994
BC150710
CCDS CCDS27370.1
RefSeq NP_001276425.1
NP_848863.1
XP_006520053.1
UniGene Mm.203208
ProteinModelPortal Q4VBE4
SMR Q4VBE4
IntAct Q4VBE4
STRING 10090.ENSMUSP00000094238
PhosphoSite Q4VBE4
MaxQB Q4VBE4
PaxDb Q4VBE4
PRIDE Q4VBE4
Ensembl ENSMUST00000058593
ENSMUST00000096494
GeneID 268780
KEGG mmu:268780
UCSC uc007vea.1
uc007veb.1
CTD 133584
MGI MGI:2146149
eggNOG NOG238064
GeneTree ENSGT00530000063501
HOGENOM HOG000112344
HOVERGEN HBG107839
InParanoid Q4VBE4
OMA FMRFKTT
OrthoDB EOG7BGHJZ
PhylomeDB Q4VBE4
TreeFam TF326548
NextBio 392491
PRO PR:Q4VBE4
Proteomes UP000000589
Bgee Q4VBE4
ExpressionAtlas Q4VBE4
Genevestigator Q4VBE4
GO GO:0005604
GO:0030054
GO:0031012
GO:0005614
GO:0045202
GO:0005539
GO:0030198
GO:0019800
GO:0010811
Gene3D 2.60.120.200
2.60.40.10
InterPro IPR013320
IPR000742
IPR013032
IPR003961
IPR013783
IPR001791
Pfam PF00008
PF00041
PF00054
PF02210
SMART SM00181
SM00060
SM00282
SUPFAM SSF49265
SSF49899
PROSITE PS00022
PS01186
PS50026
PS50853
PS50025

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0031012

extracellular matrix

PMID:21129441[1]

ECO:0000315

C

Figure 2

complete
CACAO 7886

GO:0031012

extracellular matrix

PMID:16141072[2]

ECO:0000314

C

Figure 2B Shows strong evidence via tag mapping of 3′ end initiation was correlated with a short intergenic distance when in tail-to-tail orientation with a neighboring gene suggesting a possible role in an intergenic regulatory interaction.

complete
CACAO 9317

part_of

GO:0031012

extracellular matrix

PMID:18757743[3]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0030198

extracellular matrix organization

PMID:18757743[3]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0019800

peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan

PMID:18757743[3]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0010811

positive regulation of cell-substrate adhesion

PMID:18757743[3]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0009986

cell surface

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q63HQ2

C

Seeded From UniProt

complete

part_of

GO:0005614

interstitial matrix

PMID:18757743[3]

ECO:0000314

direct assay evidence used in manual assertion

C

part_of:(EMAPA:32730)

Seeded From UniProt

complete

part_of

GO:0005604

basement membrane

PMID:18757743[3]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0005539

glycosaminoglycan binding

PMID:18757743[3]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0005509

calcium ion binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001881

F

Seeded From UniProt

complete

part_of

GO:0045202

synapse

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0770
UniProtKB-SubCell:SL-0258

C

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0964

C

Seeded From UniProt

complete

part_of

GO:0030054

cell junction

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0965

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Hu, H et al. (2011) Pikachurin interaction with dystroglycan is diminished by defective O-mannosyl glycosylation in congenital muscular dystrophy models and rescued by LARGE overexpression. Neurosci. Lett. 489 10-5 PubMed GONUTS page
  2. Carninci, P et al. (2005) The transcriptional landscape of the mammalian genome. Science 309 1559-63 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 3.4 3.5 3.6 Manabe, R et al. (2008) Transcriptome-based systematic identification of extracellular matrix proteins. Proc. Natl. Acad. Sci. U.S.A. 105 12849-54 PubMed GONUTS page