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HUMAN:MFAP2
Contents
| Species (Taxon ID) | Homo sapiens (Human). (9606) | |
| Gene Name(s) | MFAP2 (synonyms: MAGP1) | |
| Protein Name(s) | Microfibrillar-associated protein 2
MFAP-2 Microfibril-associated glycoprotein 1 MAGP MAGP-1 | |
| External Links | ||
| UniProt | P55001 | |
| EMBL | U19718 CR407678 AK222751 AL049569 AL049569 CH471134 BC015039 H27217 | |
| CCDS | CCDS174.1 CCDS44071.1 | |
| PIR | I38923 | |
| RefSeq | NP_001128719.1 NP_001128720.1 NP_002394.1 NP_059453.1 | |
| UniGene | Hs.389137 | |
| ProteinModelPortal | P55001 | |
| BioGrid | 110395 | |
| MINT | MINT-206062 | |
| STRING | 9606.ENSP00000364685 | |
| PhosphoSite | P55001 | |
| DMDM | 1708914 | |
| MaxQB | P55001 | |
| PaxDb | P55001 | |
| PRIDE | P55001 | |
| DNASU | 4237 | |
| Ensembl | ENST00000375534 ENST00000375535 | |
| GeneID | 4237 | |
| KEGG | hsa:4237 | |
| UCSC | uc001azw.3 uc001azx.3 | |
| CTD | 4237 | |
| GeneCards | GC01M017300 | |
| HGNC | HGNC:7033 | |
| HPA | HPA007354 | |
| MIM | 156790 | |
| neXtProt | NX_P55001 | |
| PharmGKB | PA30769 | |
| eggNOG | NOG42345 | |
| GeneTree | ENSGT00390000017736 | |
| HOGENOM | HOG000231186 | |
| HOVERGEN | HBG060871 | |
| InParanoid | P55001 | |
| OMA | MATSGLC | |
| OrthoDB | EOG7NCV5M | |
| PhylomeDB | P55001 | |
| TreeFam | TF333418 | |
| Reactome | REACT_150331 REACT_150366 | |
| SignaLink | P55001 | |
| GeneWiki | MFAP2 | |
| GenomeRNAi | 4237 | |
| NextBio | 16705 | |
| PRO | PR:P55001 | |
| Proteomes | UP000005640 | |
| Bgee | P55001 | |
| CleanEx | HS_MFAP2 | |
| ExpressionAtlas | P55001 | |
| Genevestigator | P55001 | |
| GO | GO:0005576 GO:0001527 GO:0030198 GO:0030220 | |
| InterPro | IPR008673 IPR003582 | |
| PANTHER | PTHR16485 | |
| Pfam | PF05507 PF01549 | |
| PROSITE | PS51670 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0001527 |
microfibril |
ECO:0000314 |
C |
Figure 3 |
complete | |||||
|
enables |
GO:0005201 |
extracellular matrix structural constituent |
ECO:0007666 |
automatically integrated combinatorial computational and experimental evidence used in manual assertion |
F |
occurs_in:(CL:0002540)|occurs_in:(CL:0002570)|occurs_in:(CL:0002551) |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0062023 |
collagen-containing extracellular matrix |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
part_of:(CL:0002540)|part_of:(CL:0002570)|part_of:(CL:0002551) |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0062023 |
collagen-containing extracellular matrix |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
part_of:(UBERON:0003688) |
Seeded From UniProt |
complete | ||
|
enables |
GO:0005201 |
extracellular matrix structural constituent |
ECO:0007666 |
automatically integrated combinatorial computational and experimental evidence used in manual assertion |
F |
occurs_in:(UBERON:0003688) |
Seeded From UniProt |
complete | ||
|
enables |
GO:0005201 |
extracellular matrix structural constituent |
ECO:0007666 |
automatically integrated combinatorial computational and experimental evidence used in manual assertion |
F |
occurs_in:(UBERON:0001155) |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0120162 |
positive regulation of cold-induced thermogenesis |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0062023 |
collagen-containing extracellular matrix |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
part_of:(UBERON:0001155) |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0048050 |
post-embryonic eye morphogenesis |
ECO:0000270 |
expression pattern evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0048048 |
embryonic eye morphogenesis |
ECO:0000270 |
expression pattern evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0001527 |
microfibril |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0001527 |
microfibril |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0030198 |
extracellular matrix organization |
Reactome:R-HSA-1474244 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005576 |
extracellular region |
Reactome:R-HSA-2161282 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
|
C |
Seeded From UniProt |
complete | |
|
part_of |
GO:0005576 |
extracellular region |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Zheng, Q et al. (2013) Investigation of age-related decline of microfibril-associated glycoprotein-1 in human skin through immunohistochemistry study. Clin Cosmet Investig Dermatol 6 317-23 PubMed GONUTS page
- ↑ 2.0 2.1 Ragelle, H et al. (2017) Comprehensive proteomic characterization of stem cell-derived extracellular matrices. Biomaterials 128 147-159 PubMed GONUTS page
- ↑ 3.0 3.1 Naba, A et al. (2017) Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics. J. Proteome Res. 16 3083-3091 PubMed GONUTS page
- ↑ 4.0 4.1 Naba, A et al. (2014) Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver. BMC Cancer 14 518 PubMed GONUTS page
- ↑ Craft, CS et al. (2014) The extracellular matrix protein MAGP1 supports thermogenesis and protects against obesity and diabetes through regulation of TGF-β. Diabetes 63 1920-32 PubMed GONUTS page
- ↑ 6.0 6.1 Hubmacher, D et al. (2014) Human eye development is characterized by coordinated expression of fibrillin isoforms. Invest. Ophthalmol. Vis. Sci. 55 7934-44 PubMed GONUTS page
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