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YEAST:TAF14
Contents
| Species (Taxon ID) | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). (559292) | |
| Gene Name(s) | TAF14 (synonyms: ANC1, CST10, SWP29, TAF30, TFG3) | |
| Protein Name(s) | Transcription initiation factor TFIID subunit 14
Actin non-complementing mutant 1 Chromosome stability protein 10 SWI/SNF chromatin-remodeling complex subunit TAF14 SWI/SNF complex 29 kDa subunit SWI/SNF complex subunit TAF14 TBP-associated factor 14 TBP-associated factor 30 kDa Transcription factor G 30 kDa subunit Transcription initiation factor TFIIF 30 kDa subunit | |
| External Links | ||
| UniProt | P35189 | |
| EMBL | U13017 Z26040 U43703 X69394 BK006949 | |
| PIR | S38568 | |
| RefSeq | NP_015196.1 | |
| PDB | 2L7E 3QRL | |
| PDBsum | 2L7E 3QRL | |
| ProteinModelPortal | P35189 | |
| SMR | P35189 | |
| BioGrid | 36052 | |
| DIP | DIP-1147N | |
| IntAct | P35189 | |
| MINT | MINT-646854 | |
| STRING | 4932.YPL129W | |
| MaxQB | P35189 | |
| PaxDb | P35189 | |
| PeptideAtlas | P35189 | |
| EnsemblFungi | [example_ID YPL129W] | |
| GeneID | 855974 | |
| KEGG | sce:YPL129W | |
| CYGD | YPL129w | |
| SGD | S000006050 | |
| eggNOG | COG5033 | |
| GeneTree | ENSGT00530000068270 | |
| HOGENOM | HOG000176324 | |
| InParanoid | P35189 | |
| KO | K03140 | |
| OMA | HPTFANP | |
| OrthoDB | EOG76DV4G | |
| BioCyc | YEAST:G3O-34028-MONOMER | |
| EvolutionaryTrace | P35189 | |
| NextBio | 980795 | |
| Proteomes | UP000002311 | |
| Genevestigator | P35189 | |
| GO | GO:0031011 GO:0016592 GO:0033100 GO:1990467 GO:1990468 GO:0005634 GO:0016514 GO:0005669 GO:0005674 GO:0000991 GO:0006200 GO:0006338 GO:0016573 GO:0042766 GO:0001111 GO:0006357 GO:0051123 GO:0006368 GO:0006366 GO:0006367 GO:0001174 | |
| InterPro | IPR016665 IPR005033 | |
| PANTHER | PTHR23195 PTHR23195:SF2 | |
| Pfam | PF03366 | |
| PIRSF | PIRSF016551 | |
| PROSITE | PS51037 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0005667 |
transcription factor complex |
ECO:0000314 |
C |
Figure 4E shows the precipitates that were electrophoresed in a SDS-10% poly- acrylamide gel. It shows by the overlap that yeast TAFs can be immunoprecipitated by antibodies against Tfg3. Antibody against Tfg3 (lane 1) or mAb 12CA5 (lane 2) was used to immunoprecipitate yeast TAFs from a complex fraction. |
complete | |||||
| GO:0005674 |
transcription factor TFIIF complex |
ECO:0000314 |
C |
Figure 5 Depicts region 4.2 showing the sequence homology between Tfg2 of bacterial cr factors. Alignment of the carboxy-terminal residues of Tfg2 with the carboxy-terminal residues of E. coli and Bacillus subtilis. |
complete | |||||
|
part_of |
GO:1990468 |
NuA3b histone acetyltransferase complex |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:1990467 |
NuA3a histone acetyltransferase complex |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0051123 |
RNA polymerase II preinitiation complex assembly |
ECO:0000305 |
curator inference used in manual assertion |
GO:0005669 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0051123 |
RNA polymerase II preinitiation complex assembly |
ECO:0000305 |
curator inference used in manual assertion |
GO:0005674 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0042766 |
nucleosome mobilization |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0033100 |
NuA3 histone acetyltransferase complex |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0033100 |
NuA3 histone acetyltransferase complex |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0031011 |
Ino80 complex |
ECO:0000353 |
physical interaction evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0031011 |
Ino80 complex |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016592 |
mediator complex |
ECO:0000353 |
physical interaction evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0016573 |
histone acetylation |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016514 |
SWI/SNF complex |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
contributes_to |
GO:0015616 |
DNA translocase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
contributes_to |
GO:0015616 |
DNA translocase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
contributes_to |
GO:0015616 |
DNA translocase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006368 |
transcription elongation from RNA polymerase II promoter |
ECO:0000305 |
curator inference used in manual assertion |
GO:0005674 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006367 |
transcription initiation from RNA polymerase II promoter |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006366 |
transcription by RNA polymerase II |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006366 |
transcription by RNA polymerase II |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006338 |
chromatin remodeling |
ECO:0000305 |
curator inference used in manual assertion |
GO:0031011 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006338 |
chromatin remodeling |
ECO:0000305 |
curator inference used in manual assertion |
GO:0016514 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005674 |
transcription factor TFIIF complex |
ECO:0000353 |
physical interaction evidence used in manual assertion |
SGD:S000003418 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005674 |
transcription factor TFIIF complex |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005674 |
transcription factor TFIIF complex |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005674 |
transcription factor TFIIF complex |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005669 |
transcription factor TFIID complex |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005669 |
transcription factor TFIID complex |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0001174 |
transcriptional start site selection at RNA polymerase II promoter |
ECO:0000305 |
curator inference used in manual assertion |
GO:0005674 |
P |
Seeded From UniProt |
complete | ||
|
contributes_to |
GO:0001139 |
RNA polymerase II complex recruiting activity |
ECO:0000305 |
curator inference used in manual assertion |
GO:0005674 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0001111 |
promoter clearance from RNA polymerase II promoter |
ECO:0000305 |
curator inference used in manual assertion |
GO:0005674 |
P |
Seeded From UniProt |
complete | ||
|
contributes_to |
GO:0016251 |
RNA polymerase II general transcription initiation factor activity |
ECO:0000305 |
curator inference used in manual assertion |
GO:0005669 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0016251 |
RNA polymerase II general transcription initiation factor activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006355 |
regulation of transcription, DNA-templated |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 1.8 Henry, NL et al. (1994) TFIIF-TAF-RNA polymerase II connection. Genes Dev. 8 2868-78 PubMed GONUTS page
- ↑ 2.0 2.1 Gilbert, TM et al. (2014) A PWWP domain-containing protein targets the NuA3 acetyltransferase complex via histone H3 lysine 36 trimethylation to coordinate transcriptional elongation at coding regions. Mol. Cell Proteomics 13 2883-95 PubMed GONUTS page
- ↑ 3.0 3.1 Sanders, SL & Weil, PA (2000) Identification of two novel TAF subunits of the yeast Saccharomyces cerevisiae TFIID complex. J. Biol. Chem. 275 13895-900 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 Shen, X et al. (2003) Involvement of actin-related proteins in ATP-dependent chromatin remodeling. Mol. Cell 12 147-55 PubMed GONUTS page
- ↑ 5.0 5.1 John, S et al. (2000) The something about silencing protein, Sas3, is the catalytic subunit of NuA3, a yTAF(II)30-containing HAT complex that interacts with the Spt16 subunit of the yeast CP (Cdc68/Pob3)-FACT complex. Genes Dev. 14 1196-208 PubMed GONUTS page
- ↑ Taverna, SD et al. (2006) Yng1 PHD finger binding to H3 trimethylated at K4 promotes NuA3 HAT activity at K14 of H3 and transcription at a subset of targeted ORFs. Mol. Cell 24 785-96 PubMed GONUTS page
- ↑ Tosi, A et al. (2013) Structure and subunit topology of the INO80 chromatin remodeler and its nucleosome complex. Cell 154 1207-19 PubMed GONUTS page
- ↑ 8.0 8.1 Dechassa, ML et al. (2008) Architecture of the SWI/SNF-nucleosome complex. Mol. Cell. Biol. 28 6010-21 PubMed GONUTS page
- ↑ Lia, G et al. (2006) Direct observation of DNA distortion by the RSC complex. Mol. Cell 21 417-25 PubMed GONUTS page
- ↑ Fischer, CJ et al. (2007) Kinetic model for the ATP-dependent translocation of Saccharomyces cerevisiae RSC along double-stranded DNA. Biochemistry 46 12416-26 PubMed GONUTS page
- ↑ Zhang, Y et al. (2006) DNA translocation and loop formation mechanism of chromatin remodeling by SWI/SNF and RSC. Mol. Cell 24 559-68 PubMed GONUTS page
- ↑ Sayre, MH et al. (1992) Reconstitution of transcription with five purified initiation factors and RNA polymerase II from Saccharomyces cerevisiae. J. Biol. Chem. 267 23376-82 PubMed GONUTS page
- ↑ 13.0 13.1 13.2 Auty, R et al. (2004) Purification of active TFIID from Saccharomyces cerevisiae. Extensive promoter contacts and co-activator function. J. Biol. Chem. 279 49973-81 PubMed GONUTS page
- ↑ Sanders, SL et al. (2002) Molecular characterization of Saccharomyces cerevisiae TFIID. Mol. Cell. Biol. 22 6000-13 PubMed GONUTS page
- ↑ 15.0 15.1 Kabani, M et al. (2005) Anc1 interacts with the catalytic subunits of the general transcription factors TFIID and TFIIF, the chromatin remodeling complexes RSC and INO80, and the histone acetyltransferase complex NuA3. Biochem. Biophys. Res. Commun. 332 398-403 PubMed GONUTS page
- ↑ Krogan, NJ et al. (2002) RNA polymerase II elongation factors of Saccharomyces cerevisiae: a targeted proteomics approach. Mol. Cell. Biol. 22 6979-92 PubMed GONUTS page
- ↑ Dastidar, RG et al. (2012) The nuclear localization of SWI/SNF proteins is subjected to oxygen regulation. Cell Biosci 2 30 PubMed GONUTS page
- ↑ Rani, PG et al. (2004) RNA polymerase II (Pol II)-TFIIF and Pol II-mediator complexes: the major stable Pol II complexes and their activity in transcription initiation and reinitiation. Mol. Cell. Biol. 24 1709-20 PubMed GONUTS page
f
n
r
- GO:0006355 ! regulation of DNA-templated transcription
- GO:0001111 ! RNA polymerase II promoter clearance
- GO:0051123 ! RNA polymerase II preinitiation complex assembly
- GO:0016251 ! RNA polymerase II general transcription initiation factor activity
- GO:0001139 ! RNA polymerase II complex recruiting activity
s
t
- GO:0001174 ! transcriptional start site selection at RNA polymerase II promoter
- GO:0005674 ! transcription factor TFIIF complex
- GO:0006366 ! transcription by RNA polymerase II
- GO:0006367 ! transcription initiation at RNA polymerase II promoter
- GO:0006368 ! transcription elongation by RNA polymerase II
- GO:0005669 ! transcription factor TFIID complex
- GO:0005667 ! transcription regulator complex
