GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.
CACAO Spring 2014
|Status||Page||Date/Time||GO Term (Aspect)||Reference||Evidence||Notes||Links|
|HUMAN:BTK||2014-01-29 17:56:38 CST||GO:0018108 peptidyl-tyrosine phosphorylation (P)||PMID:11606584||ECO:0000314 direct assay evidence used in manual assertion|
When two additional peptides incorporating either the Y753F (peptide 2) or Y759F (peptide 3) mutation were used, it was shown that Tyr753 was phosphorylated in preference to Tyr759 (Fig. 6 B).
|HUMAN:FAK2||2014-01-29 18:42:38 CST||GO:0038083 peptidyl-tyrosine autophosphorylation (P)||PMID:9545257||ECO:0000314 direct assay evidence used in manual assertion|
|HUMAN:FAK2||2014-01-29 19:02:10 CST||GO:0033673 negative regulation of kinase activity (P)||PMID:18339875||ECO:0000314 direct assay evidence used in manual assertion|
Figure 2 shows that after treatment with PF-562,271 more cells that were treated with 1.1 micro mole/L were in S and G2-M phase than other cells.
|HUMAN:CIB1||2014-01-30 21:04:19 CST||GO:0005886 plasma membrane (C)||PMID:20473878||ECO:0000314 direct assay evidence used in manual assertion|
In figure 2Aii, CIB1 is seen localized along the cell membrane indicating plasma membrane localization as visualized in H & E stains.
|HUMAN:CIB1||2014-01-30 21:17:55 CST||GO:0030291 protein serine/threonine kinase inhibitor activity (F)||PMID:20473878||ECO:0000314 direct assay evidence used in manual assertion|
|HUMAN:FOXO1||2014-02-08 11:52:15 CST||GO:0048523 negative regulation of cellular process (P)||PMID:18079193||ECO:0000314 direct assay evidence used in manual assertion|
Figure 2A shows the effect on the production of raptor by the FOX01 when exposed to 4-HT versus when not. The figure shows that over time the production of raptor decreased when exposed to 4-HT versus not.
Annotations challenged by Malexander2
|Status||Author,Group||Page||GO Term (Aspect)||Reference||Evidence||Links||Page history|
|HUMAN:FOXO1||GO:0005634 - nucleus (C)||PMID:18079193||ECO:0000314 direct assay evidence used in manual assertion||challenge||C: 1|
Team Bfast Taco
|RABIT:EAA3||GO:0070779 - D-aspartate import across plasma membrane (P)||PMID:20424168||ECO:0000315 mutant phenotype evidence used in manual assertion||challenge||C: 1|
Team What the Fox Says
|ECOLI:LAMB||GO:0015288 - porin activity (F)||PMID:24412198||ECO:0000314 direct assay evidence used in manual assertion||challenge||C: 4|
Team Chicken Day
|HUMAN:COGA1||GO:0008544 - epidermis development (P)||PMID:16754661||ECO:0000314 direct assay evidence used in manual assertion||challenge||C: 3|
Team Bacon Pancakes
|HUMAN:SHBG||GO:0007285 - primary spermatocyte growth (P)||PMID:2956126||ECO:0000255 match to sequence model evidence used in manual assertion||challenge||C: 3|
0 annotations fixed by Malexander2