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User:Malexander2

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CACAO Spring 2014

My Annotations

StatusPageDate/TimeGO Term (Aspect)ReferenceEvidenceNotesLinks
updatedbyinstructorHUMAN:BTK2014-01-29 17:56:38 CSTGO:0018108 peptidyl-tyrosine phosphorylation (P)PMID:11606584ECO:0000314 direct assay evidence used in manual assertion

When two additional peptides incorporating either the Y753F (peptide 2) or Y759F (peptide 3) mutation were used, it was shown that Tyr753 was phosphorylated in preference to Tyr759 (Fig. 6 B).

challenge
updatedbyinstructorHUMAN:FAK22014-01-29 18:42:38 CSTGO:0038083 peptidyl-tyrosine autophosphorylation (P)PMID:9545257ECO:0000314 direct assay evidence used in manual assertion

Figure 5

challenge
unacceptableHUMAN:FAK22014-01-29 19:02:10 CSTGO:0033673 negative regulation of kinase activity (P)PMID:18339875ECO:0000314 direct assay evidence used in manual assertion

Figure 2 shows that after treatment with PF-562,271 more cells that were treated with 1.1 micro mole/L were in S and G2-M phase than other cells.

challenge
updatedbyinstructorHUMAN:CIB12014-01-30 21:04:19 CSTGO:0005886 plasma membrane (C)PMID:20473878ECO:0000314 direct assay evidence used in manual assertion

In figure 2Aii, CIB1 is seen localized along the cell membrane indicating plasma membrane localization as visualized in H & E stains.

challenge
updatedbyinstructorHUMAN:CIB12014-01-30 21:17:55 CSTGO:0030291 protein serine/threonine kinase inhibitor activity (F)PMID:20473878ECO:0000314 direct assay evidence used in manual assertion

Fig 5

challenge
unacceptableHUMAN:FOXO12014-02-08 11:52:15 CSTGO:0048523 negative regulation of cellular process (P)PMID:18079193ECO:0000314 direct assay evidence used in manual assertion

Figure 2A shows the effect on the production of raptor by the FOX01 when exposed to 4-HT versus when not. The figure shows that over time the production of raptor decreased when exposed to 4-HT versus not.

challenge

acceptable:0
unacceptable:2
requires_changes:0
flagged:0

Annotations challenged by Malexander2

StatusAuthor,GroupPageGO Term (Aspect)ReferenceEvidenceLinksPage history
unacceptableAross,
Team BAMF
HUMAN:FOXO1GO:0005634 - nucleus (C)PMID:18079193ECO:0000314 direct assay evidence used in manual assertionchallengeC: 1
updatedbyinstructorKfree,
Team Bfast Taco
RABIT:EAA3GO:0070779 - D-aspartate import across plasma membrane (P)PMID:20424168ECO:0000315 mutant phenotype evidence used in manual assertionchallengeC: 1
updatedbyinstructorFclingen,
Team What the Fox Says
ECOLI:LAMBGO:0015288 - porin activity (F)PMID:24412198ECO:0000314 direct assay evidence used in manual assertionchallengeC: 4
unacceptableBmanieri,
Team Chicken Day
HUMAN:COGA1GO:0008544 - epidermis development (P)PMID:16754661ECO:0000314 direct assay evidence used in manual assertionchallengeC: 3
unacceptableAstephens2,
Team Bacon Pancakes
HUMAN:SHBGGO:0007285 - primary spermatocyte growth (P)PMID:2956126ECO:0000255 match to sequence model evidence used in manual assertionchallengeC: 3

0 annotations fixed by Malexander2

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