ECOLI:LAMB

Species (Taxon ID)	Escherichia coli (strain K12). (83333)
Gene Name(s)	lamB (synonyms: malB)
Protein Name(s)	Maltoporin Lambda receptor protein Maltose-inducible porin
External Links
UniProt	P02943
EMBL	M16643 M26131 V00298 J01648 U00006 U00096 AP009048 M24997 V00297
PIR	A03443
RefSeq	NP_418460.1 YP_492179.1
PDB	1AF6 1MAL 1MPM 1MPN 1MPO 1MPQ
PDBsum	1AF6 1MAL 1MPM 1MPN 1MPO 1MPQ
ProteinModelPortal	P02943
SMR	P02943
DIP	DIP-10082N
IntAct	P02943
STRING	511145.b4036
TCDB	1.B.3.1.1
PRIDE	P02943
EnsemblBacteria	AAC77006 BAE78038
GeneID	12933669 948548
KEGG	ecj:Y75_p3923 eco:b4036
PATRIC	32123605
EchoBASE	EB0523
EcoGene	EG10528
eggNOG	COG4580
HOGENOM	HOG000218083
KO	K02024
OMA	YNKFVLQ
OrthoDB	EOG63C0PN
BioCyc	EcoCyc:EG10528-MONOMER ECOL316407:JW3996-MONOMER MetaCyc:EG10528-MONOMER
EvolutionaryTrace	P02943
PRO	PR:P02943
Proteomes	UP000000318 UP000000625
Genevestigator	P02943
GO	GO:0045203 GO:0046930 GO:0042958 GO:0015481 GO:0015288 GO:0001618 GO:0006974 GO:0006811 GO:0042956 GO:0055085 GO:0016032
Gene3D	2.40.170.10
HAMAP	MF_01301
InterPro	IPR023738 IPR003192
Pfam	PF02264
ProDom	PD008788

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Notes	Status
	GO:0009279	cell outer membrane	PMID:10806384^[1]	ECO:0000314			C	Table 1	complete
	GO:0051119	sugar transmembrane transporter activity	PMCID: PMC235871 PMID:1100596^[2]	ECO:0000315			F	Figure 4	complete
	GO:0009597	detection of virus	PMID:2952637^[3]	ECO:0000315			P	See Table 1: Several point mutations confer resistance to bacteriophage lambda.	complete
	GO:0005363	maltose transmembrane transporter activity	PMID:1100596^[2]	ECO:0000315			F	Figure 4. Uptake kinetics of maltose by lamB mutants.	complete
enables	GO:0015288	porin activity	PMID:24412198^[4]	ECO:0000314	direct assay evidence used in manual assertion		F	Seeded From UniProt	complete
part_of	GO:0046930	pore complex	PMID:21873635^[5]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	EcoGene:EG10528 PANTHER:PTN002215166	C	Seeded From UniProt	complete
part_of	GO:0045203	integral component of cell outer membrane	PMID:21873635^[5]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	EcoGene:EG10528 PANTHER:PTN002215166	C	Seeded From UniProt	complete
part_of	GO:0031230	intrinsic component of cell outer membrane	PMID:21873635^[5]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN002215166 UniProtKB:P26466	C	Seeded From UniProt	complete
enables	GO:0015288	porin activity	PMID:21873635^[5]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	EcoGene:EG10528 PANTHER:PTN002215166	F	Seeded From UniProt	complete
enables	GO:0015144	carbohydrate transmembrane transporter activity	PMID:21873635^[5]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	EcoGene:EG11364 PANTHER:PTN002215166	F	Seeded From UniProt	complete
involved_in	GO:0006974	cellular response to DNA damage stimulus	PMID:11967071^[6]	ECO:0000270	expression pattern evidence used in manual assertion		P	Seeded From UniProt	complete
	GO:0015288	porin activity	PMID:24412198^[4]	ECO:0000314			F	Fig 6 (top) has data for lamB	complete CACAO 9275
part_of	GO:0046930	pore complex	PMID:7824948^[7]	ECO:0000314	direct assay evidence used in manual assertion		C	Seeded From UniProt	complete
part_of	GO:0045203	integral component of cell outer membrane	PMID:6444720^[8]	ECO:0000314	direct assay evidence used in manual assertion		C	Seeded From UniProt	complete
enables	GO:0042958	maltodextrin transmembrane transporter activity	PMID:6444720^[8]	ECO:0000314	direct assay evidence used in manual assertion		F	Seeded From UniProt	complete
involved_in	GO:0042956	maltodextrin transport	PMID:6444720^[8]	ECO:0000314	direct assay evidence used in manual assertion		P	Seeded From UniProt	complete
enables	GO:0015288	porin activity	PMID:7824948^[7]	ECO:0000314	direct assay evidence used in manual assertion		F	Seeded From UniProt	complete
part_of	GO:0009279	cell outer membrane	PMID:22534293^[9]	ECO:0000314	direct assay evidence used in manual assertion		C	Seeded From UniProt	complete
part_of	GO:0009279	cell outer membrane	PMID:15911532^[10]	ECO:0000314	direct assay evidence used in manual assertion		C	Seeded From UniProt	complete
part_of	GO:0009279	cell outer membrane	PMID:10806384^[1]	ECO:0000314	direct assay evidence used in manual assertion		C	Seeded From UniProt	complete
involved_in	GO:0046718	viral entry into host cell	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0001618	P	Seeded From UniProt	complete
part_of	GO:0009279	cell outer membrane	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR023738	C	Seeded From UniProt	complete
enables	GO:0015288	porin activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR003192 InterPro:IPR036998	F	Seeded From UniProt	complete
enables	GO:0015481	maltose transporting porin activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR023738	F	Seeded From UniProt	complete
involved_in	GO:0015768	maltose transport	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR023738	P	Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR003192 InterPro:IPR036998	C	Seeded From UniProt	complete
involved_in	GO:0034219	carbohydrate transmembrane transport	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR003192 InterPro:IPR036998	P	Seeded From UniProt	complete
involved_in	GO:0042956	maltodextrin transport	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR023738	P	Seeded From UniProt	complete
enables	GO:0042958	maltodextrin transmembrane transporter activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR023738	F	Seeded From UniProt	complete
part_of	GO:0009279	cell outer membrane	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000101733	C	Seeded From UniProt	complete
involved_in	GO:0015768	maltose transport	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000101733	P	Seeded From UniProt	complete
enables	GO:0015288	porin activity	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000101733	F	Seeded From UniProt	complete
enables	GO:0015288	porin activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0626	F	Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0472	C	Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0812	C	Seeded From UniProt	complete
enables	GO:0001618	virus receptor activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-1183	F	Seeded From UniProt	complete
part_of	GO:0009279	cell outer membrane	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0998 UniProtKB-SubCell:SL-0040	C	Seeded From UniProt	complete
involved_in	GO:0016032	viral process	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0945	P	Seeded From UniProt	complete
involved_in	GO:0006811	ion transport	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0406	P	Seeded From UniProt	complete
involved_in	GO:0008643	carbohydrate transport	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0762	P	Seeded From UniProt	complete
part_of	GO:0046930	pore complex	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0626	C	Seeded From UniProt	complete
edit table

Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 Molloy, MP et al. (2000) Proteomic analysis of the Escherichia coli outer membrane. Eur. J. Biochem. 267 2871-81 PubMed GONUTS page
↑ ^2.0 ^2.1 Szmelcman, S & Hofnung, M (1975) Maltose transport in Escherichia coli K-12: involvement of the bacteriophage lambda receptor. J. Bacteriol. 124 112-8 PubMed GONUTS page
↑ Gehring, K et al. (1987) Bacteriophage lambda receptor site on the Escherichia coli K-12 LamB protein. J. Bacteriol. 169 2103-6 PubMed GONUTS page
↑ ^4.0 ^4.1 Lin, XM et al. (2014) Decreased expression of LamB and Odp1 complex is crucial for antibiotic resistance in Escherichia coli. J Proteomics 98 244-53 PubMed GONUTS page
↑ ^5.0 ^5.1 ^5.2 ^5.3 ^5.4 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
↑ Khil, PP & Camerini-Otero, RD (2002) Over 1000 genes are involved in the DNA damage response of Escherichia coli. Mol. Microbiol. 44 89-105 PubMed GONUTS page
↑ ^7.0 ^7.1 Schirmer, T et al. (1995) Structural basis for sugar translocation through maltoporin channels at 3.1 A resolution. Science 267 512-4 PubMed GONUTS page
↑ ^8.0 ^8.1 ^8.2 Luckey, M & Nikaido, H (1980) Specificity of diffusion channels produced by lambda phage receptor protein of Escherichia coli. Proc. Natl. Acad. Sci. U.S.A. 77 167-71 PubMed GONUTS page
↑ Han, MJ et al. (2012) Comparative analysis of envelope proteomes in Escherichia coli B and K-12 strains. J. Microbiol. Biotechnol. 22 470-8 PubMed GONUTS page
↑ Lopez-Campistrous, A et al. (2005) Localization, annotation, and comparison of the Escherichia coli K-12 proteome under two states of growth. Mol. Cell Proteomics 4 1205-9 PubMed GONUTS page

[PMID:10806384-1] 1.0 ^1.1 Molloy, MP et al. (2000) Proteomic analysis of the Escherichia coli outer membrane. Eur. J. Biochem. 267 2871-81 PubMed GONUTS page

[PMID:1100596-2] 2.0 ^2.1 Szmelcman, S & Hofnung, M (1975) Maltose transport in Escherichia coli K-12: involvement of the bacteriophage lambda receptor. J. Bacteriol. 124 112-8 PubMed GONUTS page

[PMID:2952637-3] Gehring, K et al. (1987) Bacteriophage lambda receptor site on the Escherichia coli K-12 LamB protein. J. Bacteriol. 169 2103-6 PubMed GONUTS page

[PMID:24412198-4] 4.0 ^4.1 Lin, XM et al. (2014) Decreased expression of LamB and Odp1 complex is crucial for antibiotic resistance in Escherichia coli. J Proteomics 98 244-53 PubMed GONUTS page

[PMID:21873635-5] 5.0 ^5.1 ^5.2 ^5.3 ^5.4 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:11967071-6] Khil, PP & Camerini-Otero, RD (2002) Over 1000 genes are involved in the DNA damage response of Escherichia coli. Mol. Microbiol. 44 89-105 PubMed GONUTS page

[PMID:7824948-7] 7.0 ^7.1 Schirmer, T et al. (1995) Structural basis for sugar translocation through maltoporin channels at 3.1 A resolution. Science 267 512-4 PubMed GONUTS page

[PMID:6444720-8] 8.0 ^8.1 ^8.2 Luckey, M & Nikaido, H (1980) Specificity of diffusion channels produced by lambda phage receptor protein of Escherichia coli. Proc. Natl. Acad. Sci. U.S.A. 77 167-71 PubMed GONUTS page

[PMID:22534293-9] Han, MJ et al. (2012) Comparative analysis of envelope proteomes in Escherichia coli B and K-12 strains. J. Microbiol. Biotechnol. 22 470-8 PubMed GONUTS page

[PMID:15911532-10] Lopez-Campistrous, A et al. (2005) Localization, annotation, and comparison of the Escherichia coli K-12 proteome under two states of growth. Mol. Cell Proteomics 4 1205-9 PubMed GONUTS page

[1]

[2]

[3]

[4]

[5]

[6]

[7]

[8]

[9]

[10]

ECOLI:LAMB

Contents

Annotations

Notes

References

b

c

d

e

g

i

m

o

p

s

v

Navigation menu

Personal tools

Namespaces

Variants

Views

More

Search

Navigation

Cacao

Links

Tools