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RABIT:EAA3
Contents
| Species (Taxon ID) | Oryctolagus cuniculus (Rabbit). (9986) | |
| Gene Name(s) | SLC1A1 (synonyms: EAAC1, EAAT3) | |
| Protein Name(s) | Excitatory amino acid transporter 3
Excitatory amino-acid carrier 1 Sodium-dependent glutamate/aspartate transporter 3 Solute carrier family 1 member 1 | |
| External Links | ||
| UniProt | P31597 | |
| EMBL | L12411 | |
| PIR | S28902 | |
| RefSeq | NP_001075718.1 | |
| UniGene | Ocu.1980 | |
| ProteinModelPortal | P31597 | |
| STRING | 9986.ENSOCUP00000022489 | |
| GeneID | 100009070 | |
| CTD | 6505 | |
| eggNOG | COG1301 | |
| HOGENOM | HOG000208776 | |
| HOVERGEN | HBG000080 | |
| InParanoid | P31597 | |
| Proteomes | UP000001811 | |
| GO | GO:0016021 GO:0017153 | |
| Gene3D | 1.10.3860.10 | |
| InterPro | IPR001991 IPR018107 | |
| PANTHER | PTHR11958 | |
| Pfam | PF00375 | |
| PRINTS | PR00173 | |
| SUPFAM | SSF118215 | |
| PROSITE | PS00713 PS00714 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0070779 |
D-aspartate import |
ECO:0000315 |
P |
Figure 1 shows uptake of substrates is reduced with mutation of Met-367. |
complete | |||||
|
involved_in |
GO:0070779 |
D-aspartate import across plasma membrane |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0140009 |
L-aspartate import across plasma membrane |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005887 |
integral component of plasma membrane |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0015501 |
glutamate:sodium symporter activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005314 |
high-affinity glutamate transmembrane transporter activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005887 |
integral component of plasma membrane |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0015501 |
glutamate:sodium symporter activity |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0015108 |
chloride transmembrane transporter activity |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005314 |
high-affinity glutamate transmembrane transporter activity |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:1902476 |
chloride transmembrane transport |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0140009 |
L-aspartate import across plasma membrane |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0098712 |
L-glutamate import across plasma membrane |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0070779 |
D-aspartate import across plasma membrane |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016324 |
apical plasma membrane |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005886 |
plasma membrane |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0033229 |
cysteine transmembrane transporter activity |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005313 |
L-glutamate transmembrane transporter activity |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0015813 |
L-glutamate transmembrane transport |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0042883 |
cysteine transport |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:1903712 |
cysteine transmembrane transport |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0033229 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0015293 |
symporter activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005886 |
plasma membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0046872 |
metal ion binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0015293 |
symporter activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006865 |
amino acid transport |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016324 |
apical plasma membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Rosental, N & Kanner, BI (2010) A conserved methionine residue controls the substrate selectivity of a neuronal glutamate transporter. J. Biol. Chem. 285 21241-8 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 Kanai, Y & Hediger, MA (1992) Primary structure and functional characterization of a high-affinity glutamate transporter. Nature 360 467-71 PubMed GONUTS page
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