name: insulin receptor substrate binding
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def: "Interacting selectively and non-covalently with any of the insulin receptor substrate (IRS) proteins, adaptor proteins that bind to the transphosphorylated insulin and insulin-like growth factor receptors, are themselves phosphorylated and in turn recruit SH2 domain-containing signaling molecules to form a productive signaling complex." [PMID:12829233]
synonym: "insulin receptor substrate [protein] binding" EXACT 
synonym: "IRS [protein] binding" EXACT 
synonym: "IRS binding" EXACT 
is_a: GO:0005515 ! protein binding
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Pages in category "GO:0043560 ! insulin receptor substrate binding"
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