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CHICK:Q5F4A2

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Species (Taxon ID) Gallus gallus (Chicken). (9031)
Gene Name(s) PIK3CB (ECO:0000313 with Ensembl:ENSGALP00000008740)
Protein Name(s) Uncharacterized protein (ECO:0000313 with EMBL:CAH65032.1, ECO:0000313 with Ensembl:ENSGALP00000008740)
External Links
UniProt Q5F4A2
EMBL AADN03005719
AADN03005729
AJ851398
RefSeq NP_001026482.1
UniGene Gga.22736
STRING 9031.ENSGALP00000008740
Ensembl ENSGALT00000008754
ENSGALT00000044047
GeneID 424826
KEGG gga:424826
CTD 5291
eggNOG COG5032
GeneTree ENSGT00760000119110
HOGENOM HOG000252911
HOVERGEN HBG052721
KO K00922
OMA AMHTCLK
OrthoDB EOG70CR65
PhylomeDB Q5F4A2
TreeFam TF102031
Reactome REACT_189761
REACT_194994
REACT_196855
REACT_197520
REACT_198076
REACT_198205
REACT_230602
REACT_239808
REACT_240004
REACT_244511
REACT_244793
REACT_244921
REACT_250039
REACT_250045
REACT_251572
REACT_251680
REACT_254784
REACT_254874
NextBio 20827100
PRO PR:Q5F4A2
Proteomes UP000000539
GO GO:0005942
GO:0005886
GO:0016303
GO:0035005
GO:0005524
GO:0046934
GO:0006874
GO:0040016
GO:0007156
GO:0048015
GO:0030168
GO:0001952
Gene3D 1.10.1070.11
1.25.40.70
2.60.40.150
InterPro IPR016024
IPR000008
IPR011009
IPR000403
IPR018936
IPR003113
IPR002420
IPR000341
IPR015433
IPR001263
IPR029071
PANTHER PTHR10048
Pfam PF00454
PF00792
PF02192
PF00794
PF00613
SMART SM00142
SM00143
SM00144
SM00145
SM00146
SUPFAM SSF48371
SSF49562
SSF54236
SSF56112
PROSITE PS00915
PS00916
PS50290
PS51544
PS51547
PS51546
PS51545

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0048015

phosphatidylinositol-mediated signaling

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000005673
RGD:620899
dictyBase:DDB_G0278727
dictyBase:DDB_G0283081

P

Seeded From UniProt

complete

involved_in

GO:0046854

phosphatidylinositol phosphorylation

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0015277
FB:FBgn0015278
FB:FBgn0015279
FB:FBgn0267350
MGI:MGI:2448506
PANTHER:PTN000005673
RGD:620916
RGD:620917
SGD:S000004230
SGD:S000004296
SGD:S000005211
UniProtKB:A0A1D8PDV7
UniProtKB:P32871

P

Seeded From UniProt

complete

involved_in

GO:0036092

phosphatidylinositol-3-phosphate biosynthetic process

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1203729
MGI:MGI:2685045
PANTHER:PTN000005674
WB:WBGene00009552

P

Seeded From UniProt

complete

enables

GO:0035005

1-phosphatidylinositol-4-phosphate 3-kinase activity

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0015278
FB:FBgn0015279
PANTHER:PTN000005674
RGD:620231

F

Seeded From UniProt

complete

involved_in

GO:0030168

platelet activation

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1922019
PANTHER:PTN000799655

P

Seeded From UniProt

complete

involved_in

GO:0016477

cell migration

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000005674
UniProtKB:O42391

P

Seeded From UniProt

complete

enables

GO:0016303

1-phosphatidylinositol-3-kinase activity

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0015278
FB:FBgn0015279
MGI:MGI:1203729
MGI:MGI:1206581
MGI:MGI:1922019
PANTHER:PTN000005674
RGD:620916
RGD:620917
UniProtKB:P42336

F

Seeded From UniProt

complete

part_of

GO:0016020

membrane

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000005673
PomBase:SPAC458.05
TAIR:locus:2164401
UniProtKB:P48736

C

Seeded From UniProt

complete

involved_in

GO:0014065

phosphatidylinositol 3-kinase signaling

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0015279
PANTHER:PTN000005674
UniProtKB:O00329
UniProtKB:P42338
UniProtKB:P48736
dictyBase:DDB_G0278727
dictyBase:DDB_G0283081

P

Seeded From UniProt

complete

involved_in

GO:0006468

protein phosphorylation

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1206581
MGI:MGI:1353576
PANTHER:PTN000799655

P

Seeded From UniProt

complete

part_of

GO:0005942

phosphatidylinositol 3-kinase complex

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1206581
PANTHER:PTN000005674
RGD:620916
RGD:620917
UniProtKB:P32871
WB:WBGene00000090

C

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000005674
RGD:620231
UniProtKB:O00443
UniProtKB:P48736
dictyBase:DDB_G0278727
dictyBase:DDB_G0283081

C

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000005673
RGD:621214
UniProtKB:O00443
UniProtKB:P42356
UniProtKB:P48736
WB:WBGene00000090
WB:WBGene00006932
WB:WBGene00009552
dictyBase:DDB_G0291093

C

Seeded From UniProt

complete

involved_in

GO:0033031

positive regulation of neutrophil apoptotic process

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P42338
ensembl:ENSP00000289153

P

Seeded From UniProt

complete

part_of

GO:0030496

midbody

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P42338
ensembl:ENSP00000289153

C

Seeded From UniProt

complete

involved_in

GO:0016310

phosphorylation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P42338
ensembl:ENSP00000289153

P

Seeded From UniProt

complete

enables

GO:0016301

kinase activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P42338
ensembl:ENSP00000289153

F

Seeded From UniProt

complete

involved_in

GO:0014065

phosphatidylinositol 3-kinase signaling

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P42338
ensembl:ENSP00000289153

P

Seeded From UniProt

complete

involved_in

GO:0010628

positive regulation of gene expression

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P42338
ensembl:ENSP00000289153

P

Seeded From UniProt

complete

part_of

GO:0005730

nucleolus

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P42338
ensembl:ENSP00000289153

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P42338
ensembl:ENSP00000289153

C

Seeded From UniProt

complete

involved_in

GO:0001952

regulation of cell-matrix adhesion

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P42338
ensembl:ENSP00000289153

P

Seeded From UniProt

complete

involved_in

GO:0060055

angiogenesis involved in wound healing

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q8BTI9
ensembl:ENSMUSP00000035037

P

Seeded From UniProt

complete

enables

GO:0043560

insulin receptor substrate binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q8BTI9
ensembl:ENSMUSP00000035037

F

Seeded From UniProt

complete

involved_in

GO:0040016

embryonic cleavage

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q8BTI9
ensembl:ENSMUSP00000035037

P

Seeded From UniProt

complete

involved_in

GO:0030168

platelet activation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q8BTI9
ensembl:ENSMUSP00000035037

P

Seeded From UniProt

complete

enables

GO:0016303

1-phosphatidylinositol-3-kinase activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q8BTI9
ensembl:ENSMUSP00000035037

F

Seeded From UniProt

complete

involved_in

GO:0009611

response to wounding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q8BTI9
ensembl:ENSMUSP00000035037

P

Seeded From UniProt

complete

involved_in

GO:0007156

homophilic cell adhesion via plasma membrane adhesion molecules

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q8BTI9
ensembl:ENSMUSP00000035037

P

Seeded From UniProt

complete

involved_in

GO:0006874

cellular calcium ion homeostasis

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q8BTI9
ensembl:ENSMUSP00000035037

P

Seeded From UniProt

complete

involved_in

GO:0001952

regulation of cell-matrix adhesion

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q8BTI9
ensembl:ENSMUSP00000035037

P

Seeded From UniProt

complete

involved_in

GO:0001935

endothelial cell proliferation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q8BTI9
ensembl:ENSMUSP00000035037

P

Seeded From UniProt

complete

involved_in

GO:0014065

phosphatidylinositol 3-kinase signaling

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR037702

P

Seeded From UniProt

complete

enables

GO:0016301

kinase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR018936
InterPro:IPR036940

F

Seeded From UniProt

complete

enables

GO:0016303

1-phosphatidylinositol-3-kinase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR008290

F

Seeded From UniProt

complete

enables

GO:0035004

phosphatidylinositol 3-kinase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR037702

F

Seeded From UniProt

complete

involved_in

GO:0046854

phosphatidylinositol phosphorylation

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR008290
InterPro:IPR015433

P

Seeded From UniProt

complete

involved_in

GO:0048015

phosphatidylinositol-mediated signaling

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR008290
InterPro:IPR015433

P

Seeded From UniProt

complete

enables

GO:0046934

phosphatidylinositol-4,5-bisphosphate 3-kinase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:2.7.1.153

F

Seeded From UniProt

complete

involved_in

GO:0016310

phosphorylation

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0418

P

Seeded From UniProt

complete

enables

GO:0016301

kinase activity

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0418

F

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0067

F

Seeded From UniProt

complete

enables

GO:0000166

nucleotide binding

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0547

F

Seeded From UniProt

complete

enables

GO:0016740

transferase activity

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0808

F

Seeded From UniProt

complete

enables

GO:0016301

kinase activity

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000415644

F

Seeded From UniProt

complete

enables

GO:0016740

transferase activity

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000415644

F

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000114506

F

Seeded From UniProt

complete

involved_in

GO:0048015

phosphatidylinositol-mediated signaling

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000399976

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.00 1.01 1.02 1.03 1.04 1.05 1.06 1.07 1.08 1.09 1.10 1.11 1.12 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page