name: phosphatidylinositol 3-kinase complex
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def: "A protein complex capable of phosphatidylinositol 3-kinase activity and containing subunits of any phosphatidylinositol 3-kinase (PI3K) enzyme. These complexes are divided in three classes (called I, II and III) that differ for their presence across taxonomic groups and for the type of their constituents. Catalytic subunits of phosphatidylinositol 3-kinase enzymes are present in all 3 classes; regulatory subunits of phosphatidylinositol 3-kinase enzymes are present in classes I and III; adaptor proteins have been observed in class II complexes and may be present in other classes too." [GOC:bf, PMID:24587488]
comment: For discussion of membrane association, please see https://sourceforge.net/p/geneontology/ontology-requests/11559/
synonym: "1-phosphatidylinositol 3-kinase complex" EXACT 
synonym: "phosphoinositide 3-kinase complex" EXACT 
synonym: "PI3-kinase p85-subunit alpha- PI3-kinase p110 complex" NARROW [CORUM:2575]
synonym: "PI3K complex" EXACT 
synonym: "PIK3C3-PIK3R4 complex" NARROW [CORUM:429]
synonym: "PIK3CA-PIK3R1 complex" NARROW [CORUM:439]
is_a: GO:0061695 ! transferase complex, transferring phosphorus-containing groups
is_a: GO:0098796 ! membrane protein complex
relationship: part_of: GO:0019898 ! extrinsic component of membrane
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Pages in category "GO:0005942 ! phosphatidylinositol 3-kinase complex"
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