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Category:GO:0005942 ! phosphatidylinositol 3-kinase complex

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DAG for GO:0005942id: GO:0005942

name: phosphatidylinositol 3-kinase complex
namespace: cellular_component
def: "A protein complex capable of phosphatidylinositol 3-kinase activity and containing subunits of any phosphatidylinositol 3-kinase (PI3K) enzyme. These complexes are divided in three classes (called I, II and III) that differ for their presence across taxonomic groups and for the type of their constituents. Catalytic subunits of phosphatidylinositol 3-kinase enzymes are present in all 3 classes; regulatory subunits of phosphatidylinositol 3-kinase enzymes are present in classes I and III; adaptor proteins have been observed in class II complexes and may be present in other classes too." [GOC:bf, PMID:24587488]
comment: For discussion of membrane association, please see
subset: goslim_pir
synonym: "1-phosphatidylinositol 3-kinase complex" EXACT []
synonym: "phosphoinositide 3-kinase complex" EXACT [GOC:curators]
synonym: "PI3-kinase p85-subunit alpha- PI3-kinase p110 complex" NARROW [CORUM:2575]
synonym: "PI3K complex" EXACT []
synonym: "PIK3C3-PIK3R4 complex" NARROW [CORUM:429]
synonym: "PIK3CA-PIK3R1 complex" NARROW [CORUM:439]
is_a: GO:0044425 ! membrane part
is_a: GO:0061695 ! transferase complex, transferring phosphorus-containing groups
relationship: part_of: GO:0019898 ! extrinsic component of membrane


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