CHICK:B6RCQ2

Species (Taxon ID)	Gallus gallus (Chicken). (9031)
Gene Name(s)	SOCS1 (ECO:0000313 with Ensembl:ENSGALP00000011581)
Protein Name(s)	Suppressor of cytokine signaling 1 (ECO:0000313 with EMBL:ABV03592.1) Uncharacterized protein (ECO:0000313 with Ensembl:ENSGALP00000011581)
External Links
UniProt	B6RCQ2
EMBL	AADN03006945 EF554725
RefSeq	NP_001131120.1
UniGene	Gga.48264
STRING	9031.ENSGALP00000011581
Ensembl	ENSGALT00000011595
GeneID	416630
KEGG	gga:416630
CTD	8651
eggNOG	NOG298538
GeneTree	ENSGT00760000119136
HOGENOM	HOG000236320
HOVERGEN	HBG002457
KO	K04694
OMA	ACGFYWG
OrthoDB	EOG7TMZSZ
PhylomeDB	B6RCQ2
TreeFam	TF321368
Reactome	REACT_196766 REACT_197455 REACT_197530 REACT_197533 REACT_197538 REACT_197548 REACT_255374
NextBio	20820060
PRO	PR:B6RCQ2
Proteomes	UP000000539
GO	GO:0005737 GO:0019210 GO:0071230 GO:0019221 GO:0045444 GO:0007259 GO:0046627 GO:0042518 GO:0016567 GO:0060334
Gene3D	3.30.505.10
InterPro	IPR000980 IPR028413 IPR028411 IPR001496
PANTHER	PTHR10385 PTHR10385:SF5
Pfam	PF00017 PF07525
SMART	SM00252 SM00969
SUPFAM	SSF55550
PROSITE	PS50001 PS50225

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Notes	Status
enables	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:109277 PANTHER:PTN000806614 RGD:3329 RGD:621042	F	Seeded From UniProt	complete
involved_in	GO:0046854	phosphatidylinositol phosphorylation	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0020622 PANTHER:PTN000806614 UniProtKB:P23727	P	Seeded From UniProt	complete
involved_in	GO:0046627	negative regulation of insulin receptor signaling pathway	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1201791 MGI:MGI:1354910 PANTHER:PTN000043896	P	Seeded From UniProt	complete
part_of	GO:0005942	phosphatidylinositol 3-kinase complex	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:109277 PANTHER:PTN000806614 RGD:3329 UniProtKB:P23727 WB:WBGene00000001	C	Seeded From UniProt	complete
involved_in	GO:0033673	negative regulation of kinase activity	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0019210	P	Seeded From UniProt	complete
involved_in	GO:0043551	regulation of phosphatidylinositol 3-kinase activity	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0046935	P	Seeded From UniProt	complete
involved_in	GO:0046426	negative regulation of receptor signaling pathway via JAK-STAT	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O15524 ensembl:ENSP00000496577	P	Seeded From UniProt	complete
involved_in	GO:0045591	positive regulation of regulatory T cell differentiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O15524 ensembl:ENSP00000496577	P	Seeded From UniProt	complete
involved_in	GO:0042532	negative regulation of tyrosine phosphorylation of STAT protein	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O15524 ensembl:ENSP00000496577	P	Seeded From UniProt	complete
part_of	GO:0036464	cytoplasmic ribonucleoprotein granule	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O15524 ensembl:ENSP00000496577	C	Seeded From UniProt	complete
enables	GO:0019901	protein kinase binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O15524 ensembl:ENSP00000496577	F	Seeded From UniProt	complete
part_of	GO:0005654	nucleoplasm	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O15524 ensembl:ENSP00000496577	C	Seeded From UniProt	complete
enables	GO:0005159	insulin-like growth factor receptor binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O15524 ensembl:ENSP00000496577	F	Seeded From UniProt	complete
involved_in	GO:0071230	cellular response to amino acid stimulus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O35716 ensembl:ENSMUSP00000155530	P	Seeded From UniProt	complete
involved_in	GO:0050707	regulation of cytokine secretion	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O35716 ensembl:ENSMUSP00000155530	P	Seeded From UniProt	complete
involved_in	GO:0046627	negative regulation of insulin receptor signaling pathway	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O35716 ensembl:ENSMUSP00000155530	P	Seeded From UniProt	complete
involved_in	GO:0046426	negative regulation of receptor signaling pathway via JAK-STAT	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O35716 ensembl:ENSMUSP00000155530	P	Seeded From UniProt	complete
involved_in	GO:0046425	regulation of receptor signaling pathway via JAK-STAT	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O35716 ensembl:ENSMUSP00000155530	P	Seeded From UniProt	complete
involved_in	GO:0045444	fat cell differentiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O35716 ensembl:ENSMUSP00000155530	P	Seeded From UniProt	complete
involved_in	GO:0043377	negative regulation of CD8-positive, alpha-beta T cell differentiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O35716 ensembl:ENSMUSP00000155530	P	Seeded From UniProt	complete
involved_in	GO:0043372	positive regulation of CD4-positive, alpha-beta T cell differentiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O35716 ensembl:ENSMUSP00000155530	P	Seeded From UniProt	complete
involved_in	GO:0042532	negative regulation of tyrosine phosphorylation of STAT protein	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O35716 ensembl:ENSMUSP00000155530	P	Seeded From UniProt	complete
involved_in	GO:0042509	regulation of tyrosine phosphorylation of STAT protein	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O35716 ensembl:ENSMUSP00000155530	P	Seeded From UniProt	complete
involved_in	GO:0019221	cytokine-mediated signaling pathway	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O35716 ensembl:ENSMUSP00000155530	P	Seeded From UniProt	complete
enables	GO:0019210	kinase inhibitor activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O35716 ensembl:ENSMUSP00000155530	F	Seeded From UniProt	complete
involved_in	GO:0010533	regulation of activation of Janus kinase activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O35716 ensembl:ENSMUSP00000155530	P	Seeded From UniProt	complete
involved_in	GO:0007259	receptor signaling pathway via JAK-STAT	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O35716 ensembl:ENSMUSP00000155530	P	Seeded From UniProt	complete
involved_in	GO:0001932	regulation of protein phosphorylation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O35716 ensembl:ENSMUSP00000155530	P	Seeded From UniProt	complete
part_of	GO:0036464	cytoplasmic ribonucleoprotein granule	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q4JHT5 ensembl:ENSP00000496577	C	Seeded From UniProt	complete
part_of	GO:0005654	nucleoplasm	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q4JHT5 ensembl:ENSP00000496577	C	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR028411	C	Seeded From UniProt	complete
involved_in	GO:0035556	intracellular signal transduction	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR036036	P	Seeded From UniProt	complete
involved_in	GO:0046426	negative regulation of receptor signaling pathway via JAK-STAT	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR028411	P	Seeded From UniProt	complete
involved_in	GO:0060334	regulation of interferon-gamma-mediated signaling pathway	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR028411	P	Seeded From UniProt	complete
involved_in	GO:0016567	protein ubiquitination	GO_REF:0000041	ECO:0000322	imported manually asserted information used in automatic assertion	UniPathway:UPA00143	P	Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 ^1.2 ^1.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:21873635-1] 1.0 ^1.1 ^1.2 ^1.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

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CHICK:B6RCQ2

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