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DROME:P91634

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Species (Taxon ID) Drosophila melanogaster (Fruit fly). (7227)
Gene Name(s) No Information Provided. (synonyms: dp110 (ECO:0000313 with EMBL:ABG88073.1))
Protein Name(s) PI-3 kinase (ECO:0000313 with EMBL:ABG88073.1)

Phosphoinositide 3-kinase, Dp110 (ECO:0000313 with EMBL:CAA70291.1) Pi3K92E, isoform A (ECO:0000313 with EMBL:AAF55792.1) Pi3K92E, isoform B (ECO:0000313 with EMBL:AAN14359.1) Pi3K92E, isoform C (ECO:0000313 with EMBL:AGB96150.1) Putative uncharacterized protein Pi3K92E (ECO:0000313 with EMBL:CCB63076.1) SD05105p (ECO:0000313 with EMBL:AAO24928.1)

External Links
UniProt P91634
EMBL AE014297
AE014297
BT003173
DQ792599
DQ792600
AE014297
Y09070
FR870118
FR870119
FR870121
FR870122
FR870124
FR870125
FR870126
FR870127
FR870128
PIR T13950
RefSeq NP_001262770.1
NP_650902.1
NP_732536.1
UniGene Dm.1876
DIP DIP-21625N
MINT MINT-935585
STRING 7227.FBpp0083348
EnsemblMetazoa FBtr0083940
FBtr0083941
FBtr0334643
GeneID 42446
KEGG dme:Dmel_CG4141
UCSC CG4141-RA
CTD 42446
FlyBase FBgn0015279
eggNOG COG5032
KOG0904
GeneTree ENSGT00760000119110
KO K00922
OMA DIFHELP
OrthoDB EOG70CR65
BRENDA 2.7.1.137
Reactome R-DME-109704
R-DME-114604
R-DME-1257604
R-DME-1660499
R-DME-198203
R-DME-210993
R-DME-2730905
R-DME-4420097
R-DME-912631
R-DME-983695
GenomeRNAi 42446
NextBio 828825
Proteomes UP000000803
GO GO:0005622
GO:0005943
GO:0016303
GO:0035005
GO:0001727
GO:0035004
GO:0046934
GO:0017124
GO:0006914
GO:0005975
GO:0016049
GO:0009267
GO:0048813
GO:0055115
GO:0007390
GO:0002168
GO:0008286
GO:0036335
GO:0002164
GO:0030536
GO:0007436
GO:0006629
GO:0007552
GO:0035264
GO:0010507
GO:0042059
GO:0016322
GO:0048477
GO:0030707
GO:0046854
GO:0036092
GO:0048015
GO:0016310
GO:0030307
GO:0045793
GO:0045927
GO:0045572
GO:0046622
GO:0045727
GO:0042127
GO:0008361
GO:0050773
GO:0048169
GO:0007346
GO:0040014
GO:0046620
GO:2000377
GO:0051823
GO:0006979
GO:0060074
GO:0051124
Gene3D 1.10.1070.11
1.25.40.70
2.60.40.150
InterPro IPR016024
IPR000008
IPR011009
IPR000403
IPR018936
IPR003113
IPR002420
IPR000341
IPR015433
IPR001263
IPR029071
PANTHER PTHR10048
Pfam PF00454
PF00792
PF02192
PF00794
PF00613
SMART SM00142
SM00143
SM00144
SM00145
SM00146
SUPFAM SSF48371
SSF49562
SSF54236
SSF56112
PROSITE PS00915
PS00916
PS50290
PS51544
PS51547
PS51546
PS51545

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001727

lipid kinase activity

PMID:17041587[1]

IDA: Inferred from Direct Assay

-

F

Seeded From UniProt

GO:0002164

larval development

PMID:16182527[2]

IMP: Inferred from Mutant Phenotype

-

P

Seeded From UniProt

GO:0002168

instar larval development

PMID:16182526[3]

IMP: Inferred from Mutant Phenotype

-

P

Seeded From UniProt

GO:0002250

adaptive immune response

GO_REF:0000033

IBA: Inferred from Biological aspect of Ancestor

PANTHER:PTN000799655

P

Seeded From UniProt

GO:0005622

intracellular

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR015433

C

Seeded From UniProt

GO:0005622

intracellular

GO_REF:0000033

IBA: Inferred from Biological aspect of Ancestor

PANTHER:PTN000005674

C

Seeded From UniProt

GO:0005886

plasma membrane

GO_REF:0000033

IBA: Inferred from Biological aspect of Ancestor

PANTHER:PTN000005674

C

Seeded From UniProt

GO:0005943

phosphatidylinositol 3-kinase complex, class IA

PMID:8978685[4]

IPI: Inferred from Physical Interaction

FB:FBgn0020622

C

Seeded From UniProt

GO:0005943

phosphatidylinositol 3-kinase complex, class IA

PMID:9255069[5]

NAS: Non-traceable Author Statement

-

C

Seeded From UniProt

GO:0005975

carbohydrate metabolic process

PMID:21464442[6]

IMP: Inferred from Mutant Phenotype

-

P

Seeded From UniProt

GO:0006468

protein phosphorylation

GO_REF:0000033

IBA: Inferred from Biological aspect of Ancestor

PANTHER:PTN000799655

P

Seeded From UniProt

GO:0006629

lipid metabolic process

PMID:21464442[6]

IMP: Inferred from Mutant Phenotype

-

P

Seeded From UniProt

GO:0006914

autophagy

PMID:15296715[7]

IMP: Inferred from Mutant Phenotype

-

P

Seeded From UniProt

GO:0006979

response to oxidative stress

PMID:16155123[8]

IMP: Inferred from Mutant Phenotype

-

P

Seeded From UniProt

GO:0007346

regulation of mitotic cell cycle

PMID:21516128[9]

IMP: Inferred from Mutant Phenotype

-

P

Seeded From UniProt

GO:0007390

germ-band shortening

PMID:16774996[10]

IMP: Inferred from Mutant Phenotype

-

P

Seeded From UniProt

GO:0007436

larval salivary gland morphogenesis

PMID:15963974[11]

IMP: Inferred from Mutant Phenotype

-

P

Seeded From UniProt

GO:0007552

metamorphosis

PMID:16182527[2]

IMP: Inferred from Mutant Phenotype

-

P

Seeded From UniProt

GO:0008286

insulin receptor signaling pathway

PMID:11782950[12]

NAS: Non-traceable Author Statement

-

P

Seeded From UniProt

GO:0008286

insulin receptor signaling pathway

PMID:11897402[13]

TAS: Traceable Author Statement

-

P

Seeded From UniProt

GO:0008361

regulation of cell size

PMID:10508611[14]

IMP: Inferred from Mutant Phenotype

-

P

Seeded From UniProt

GO:0008361

regulation of cell size

PMID:11897402[13]

NAS: Non-traceable Author Statement

-

P

Seeded From UniProt

GO:0009267

cellular response to starvation

PMID:19540338[15]

IMP: Inferred from Mutant Phenotype

-

P

Seeded From UniProt

GO:0010507

negative regulation of autophagy

PMID:19540338[15]

IMP: Inferred from Mutant Phenotype

-

P

Seeded From UniProt

GO:0010906

regulation of glucose metabolic process

PMID:25994086[16]

IMP: Inferred from Mutant Phenotype

-

P

Seeded From UniProt

GO:0014065

phosphatidylinositol 3-kinase signaling

GO_REF:0000033

IBA: Inferred from Biological aspect of Ancestor

PANTHER:PTN000005674

P

Seeded From UniProt

GO:0016049

cell growth

PMID:12559758[17]

TAS: Traceable Author Statement

-

P

Seeded From UniProt

GO:0016301

kinase activity

GO_REF:0000038

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0418

F

Seeded From UniProt

GO:0016303

1-phosphatidylinositol-3-kinase activity

GO_REF:0000003

IEA: Inferred from Electronic Annotation

EC:2.7.1.137

F

Seeded From UniProt

GO:0016303

1-phosphatidylinositol-3-kinase activity

PMID:10908587[18]

NAS: Non-traceable Author Statement

-

F

Seeded From UniProt

GO:0016303

1-phosphatidylinositol-3-kinase activity

PMID:8978685[4]

IDA: Inferred from Direct Assay

-

F

Seeded From UniProt

GO:0016303

1-phosphatidylinositol-3-kinase activity

PMID:9255069[5]

ISS: Inferred from Sequence or Structural Similarity

HGNC:8975

F

Seeded From UniProt

GO:0016310

phosphorylation

GO_REF:0000038

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0418

P

Seeded From UniProt

GO:0016310

phosphorylation

PMID:10908587[18]

NAS: Non-traceable Author Statement

-

P

Seeded From UniProt

GO:0016322

neuron remodeling

PMID:24068890[19]

IMP: Inferred from Mutant Phenotype

-

P

Seeded From UniProt

GO:0016740

transferase activity

GO_REF:0000038

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0808

F

Seeded From UniProt

GO:0016773

phosphotransferase activity, alcohol group as acceptor

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000403
InterPro:IPR018936

F

Seeded From UniProt

GO:0017124

SH3 domain binding

PMID:14701751[20]

IPI: Inferred from Physical Interaction

FB:FBgn0004638

F

Seeded From UniProt

GO:0030168

platelet activation

GO_REF:0000033

IBA: Inferred from Biological aspect of Ancestor

PANTHER:PTN000799655

P

Seeded From UniProt

GO:0030307

positive regulation of cell growth

PMID:11782950[12]

NAS: Non-traceable Author Statement

-

P

Seeded From UniProt

GO:0030307

positive regulation of cell growth

PMID:13678953[21]

TAS: Traceable Author Statement

-

P

Seeded From UniProt

GO:0030536

larval feeding behavior

PMID:16150727[22]

IMP: Inferred from Mutant Phenotype

-

P

Seeded From UniProt

GO:0030707

ovarian follicle cell development

PMID:26205122[23]

IMP: Inferred from Mutant Phenotype

-

P

Seeded From UniProt

GO:0035004

phosphatidylinositol 3-kinase activity

PMID:8978685[4]

ISS: Inferred from Sequence or Structural Similarity

HGNC:8975

F

Seeded From UniProt

GO:0035004

phosphatidylinositol 3-kinase activity

PMID:8978685[4]

ISS: Inferred from Sequence or Structural Similarity

HGNC:8976

F

Seeded From UniProt

GO:0035004

phosphatidylinositol 3-kinase activity

PMID:8978685[4]

ISS: Inferred from Sequence or Structural Similarity

HGNC:8977

F

Seeded From UniProt

GO:0035005

1-phosphatidylinositol-4-phosphate 3-kinase activity

GO_REF:0000003

IEA: Inferred from Electronic Annotation

EC:2.7.1.154

F

Seeded From UniProt

GO:0035005

1-phosphatidylinositol-4-phosphate 3-kinase activity

PMID:8978685[4]

IDA: Inferred from Direct Assay

-

F

Seeded From UniProt

GO:0035005

1-phosphatidylinositol-4-phosphate 3-kinase activity

PMID:9255069[5]

ISS: Inferred from Sequence or Structural Similarity

HGNC:8975

F

Seeded From UniProt

GO:0035264

multicellular organism growth

PMID:21464442[6]

IMP: Inferred from Mutant Phenotype

-

P

Seeded From UniProt

GO:0036092

phosphatidylinositol-3-phosphate biosynthetic process

GO_REF:0000003

IEA: Inferred from Electronic Annotation

EC:2.7.1.137

P

Seeded From UniProt

GO:0036092

phosphatidylinositol-3-phosphate biosynthetic process

PMID:10908587[18]

NAS: Non-traceable Author Statement

-

P

Seeded From UniProt

GO:0036092

phosphatidylinositol-3-phosphate biosynthetic process

PMID:8978685[4]

IDA: Inferred from Direct Assay

-

P

Seeded From UniProt

GO:0036092

phosphatidylinositol-3-phosphate biosynthetic process

PMID:9255069[5]

ISS: Inferred from Sequence or Structural Similarity

HGNC:8975

P

Seeded From UniProt

GO:0036335

intestinal stem cell homeostasis

PMID:25367037[24]

IGI: Inferred from Genetic Interaction

FB:FBgn0262458

P

Seeded From UniProt

GO:0040014

regulation of multicellular organism growth

PMID:11897402[13]

NAS: Non-traceable Author Statement

-

P

Seeded From UniProt

GO:0040014

regulation of multicellular organism growth

PMID:16182526[3]

IMP: Inferred from Mutant Phenotype

-

P

Seeded From UniProt

GO:0040014

regulation of multicellular organism growth

PMID:16182527[2]

IMP: Inferred from Mutant Phenotype

-

P

Seeded From UniProt

GO:0042059

negative regulation of epidermal growth factor receptor signaling pathway

PMID:14701751[20]

IGI: Inferred from Genetic Interaction

FB:FBgn0003731

P

Seeded From UniProt

GO:0042059

negative regulation of epidermal growth factor receptor signaling pathway

PMID:14701751[20]

IGI: Inferred from Genetic Interaction

FB:FBgn0004569

P

Seeded From UniProt

GO:0042127

regulation of cell proliferation

PMID:10508611[14]

IMP: Inferred from Mutant Phenotype

-

P

Seeded From UniProt

GO:0045087

innate immune response

GO_REF:0000033

IBA: Inferred from Biological aspect of Ancestor

PANTHER:PTN000799655

P

Seeded From UniProt

GO:0045572

positive regulation of imaginal disc growth

PMID:17041587[1]

IMP: Inferred from Mutant Phenotype

-

P

Seeded From UniProt

GO:0045572

positive regulation of imaginal disc growth

PMID:8978685[4]

IMP: Inferred from Mutant Phenotype

-

P

Seeded From UniProt

GO:0045727

positive regulation of translation

PMID:17371599[25]

IMP: Inferred from Mutant Phenotype

-

P

Seeded From UniProt

GO:0045793

positive regulation of cell size

PMID:11128988[26]

TAS: Traceable Author Statement

-

P

Seeded From UniProt

GO:0045793

positive regulation of cell size

PMID:13678953[21]

TAS: Traceable Author Statement

-

P

Seeded From UniProt

GO:0045793

positive regulation of cell size

PMID:22555456[27]

IMP: Inferred from Mutant Phenotype

-

P

Seeded From UniProt

GO:0045927

positive regulation of growth

PMID:11128988[26]

TAS: Traceable Author Statement

-

P

Seeded From UniProt

GO:0046620

regulation of organ growth

PMID:11377964[28]

NAS: Non-traceable Author Statement

-

P

Seeded From UniProt

GO:0046620

regulation of organ growth

PMID:11897402[13]

NAS: Non-traceable Author Statement

-

P

Seeded From UniProt

GO:0046622

positive regulation of organ growth

PMID:10679387[29]

NAS: Non-traceable Author Statement

-

P

Seeded From UniProt

GO:0046622

positive regulation of organ growth

PMID:10962553[30]

IMP: Inferred from Mutant Phenotype

-

P

Seeded From UniProt

GO:0046622

positive regulation of organ growth

PMID:8978685[4]

IMP: Inferred from Mutant Phenotype

-

P

Seeded From UniProt

GO:0046854

phosphatidylinositol phosphorylation

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR015433

P

Seeded From UniProt

GO:0046854

phosphatidylinositol phosphorylation

PMID:11128988[26]

TAS: Traceable Author Statement

-

P

Seeded From UniProt

GO:0046854

phosphatidylinositol phosphorylation

PMID:8978685[4]

IDA: Inferred from Direct Assay

-

P

Seeded From UniProt

GO:0046854

phosphatidylinositol phosphorylation

PMID:9255069[5]

ISS: Inferred from Sequence or Structural Similarity

HGNC:8975

P

Seeded From UniProt

GO:0046934

phosphatidylinositol-4,5-bisphosphate 3-kinase activity

GO_REF:0000003

IEA: Inferred from Electronic Annotation

EC:2.7.1.153

F

Seeded From UniProt

GO:0046934

phosphatidylinositol-4,5-bisphosphate 3-kinase activity

PMID:8978685[4]

IDA: Inferred from Direct Assay

-

F

Seeded From UniProt

GO:0046934

phosphatidylinositol-4,5-bisphosphate 3-kinase activity

PMID:9255069[5]

ISS: Inferred from Sequence or Structural Similarity

HGNC:8975

F

Seeded From UniProt

GO:0048015

phosphatidylinositol-mediated signaling

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR015433

P

Seeded From UniProt

GO:0048169

regulation of long-term neuronal synaptic plasticity

PMID:17021175[31]

IDA: Inferred from Direct Assay

-

P

Seeded From UniProt

GO:0048477

oogenesis

PMID:17041587[1]

IMP: Inferred from Mutant Phenotype

-

P

Seeded From UniProt

GO:0048813

dendrite morphogenesis

PMID:17021175[31]

IDA: Inferred from Direct Assay

-

P

Seeded From UniProt

GO:0050773

regulation of dendrite development

PMID:19778508[32]

IMP: Inferred from Mutant Phenotype

-

P

Seeded From UniProt

GO:0051124

synaptic growth at neuromuscular junction

PMID:22319582[33]

IMP: Inferred from Mutant Phenotype

-

P

Seeded From UniProt

GO:0051823

regulation of synapse structural plasticity

PMID:22954894[34]

IMP: Inferred from Mutant Phenotype

-

P

Seeded From UniProt

GO:0055115

entry into diapause

PMID:17043223[35]

IMP: Inferred from Mutant Phenotype

-

P

Seeded From UniProt

GO:0060074

synapse maturation

PMID:17021175[31]

IDA: Inferred from Direct Assay

-

P

Seeded From UniProt

GO:0060326

cell chemotaxis

GO_REF:0000033

IBA: Inferred from Biological aspect of Ancestor

PANTHER:PTN000799655

P

Seeded From UniProt

GO:2000377

regulation of reactive oxygen species metabolic process

PMID:20203043[36]

IGI: Inferred from Genetic Interaction

FB:FBgn0283499

P

Seeded From UniProt

GO:0006954

inflammatory response

GO_REF:0000033

IBA: Inferred from Biological aspect of Ancestor

PANTHER:PTN000799697

P

Seeded From UniProt

GO:0045887

positive regulation of synaptic growth at neuromuscular junction

PMID:17021175[31]

IDA: Inferred from Direct Assay

P

Figure 2A shows an increase in synapse number after expression of PI3K

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 Orme, MH et al. (2006) Input from Ras is required for maximal PI(3)K signalling in Drosophila. Nat. Cell Biol. 8 1298-302 PubMed GONUTS page
  2. 2.0 2.1 2.2 Mirth, C et al. (2005) The role of the prothoracic gland in determining critical weight for metamorphosis in Drosophila melanogaster. Curr. Biol. 15 1796-807 PubMed GONUTS page
  3. 3.0 3.1 Caldwell, PE et al. (2005) Ras activity in the Drosophila prothoracic gland regulates body size and developmental rate via ecdysone release. Curr. Biol. 15 1785-95 PubMed GONUTS page
  4. 4.00 4.01 4.02 4.03 4.04 4.05 4.06 4.07 4.08 4.09 4.10 Leevers, SJ et al. (1996) The Drosophila phosphoinositide 3-kinase Dp110 promotes cell growth. EMBO J. 15 6584-94 PubMed GONUTS page
  5. 5.0 5.1 5.2 5.3 5.4 5.5 Vanhaesebroeck, B et al. (1997) Phosphoinositide 3-kinases: a conserved family of signal transducers. Trends Biochem. Sci. 22 267-72 PubMed GONUTS page
  6. 6.0 6.1 6.2 Murillo-Maldonado, JM et al. (2011) Drosophila insulin pathway mutants affect visual physiology and brain function besides growth, lipid, and carbohydrate metabolism. Diabetes 60 1632-6 PubMed GONUTS page
  7. Rusten, TE et al. (2004) Programmed autophagy in the Drosophila fat body is induced by ecdysone through regulation of the PI3K pathway. Dev. Cell 7 179-92 PubMed GONUTS page
  8. Yang, Y et al. (2005) Inactivation of Drosophila DJ-1 leads to impairments of oxidative stress response and phosphatidylinositol 3-kinase/Akt signaling. Proc. Natl. Acad. Sci. U.S.A. 102 13670-5 PubMed GONUTS page
  9. Willecke, M et al. (2011) Loss of PI3K blocks cell-cycle progression in a Drosophila tumor model. Oncogene 30 4067-74 PubMed GONUTS page
  10. Herranz, H et al. (2006) calderón encodes an organic cation transporter of the major facilitator superfamily required for cell growth and proliferation of Drosophila tissues. Development 133 2617-25 PubMed GONUTS page
  11. Takeo, S et al. (2005) Expression of a secreted form of Dally, a Drosophila glypican, induces overgrowth phenotype by affecting action range of Hedgehog. Dev. Biol. 284 204-18 PubMed GONUTS page
  12. 12.0 12.1 Johnston, LA & Gallant, P (2002) Control of growth and organ size in Drosophila. Bioessays 24 54-64 PubMed GONUTS page
  13. 13.0 13.1 13.2 13.3 Claeys, I et al. (2002) Insulin-related peptides and their conserved signal transduction pathway. Peptides 23 807-16 PubMed GONUTS page
  14. 14.0 14.1 Weinkove, D et al. (1999) Regulation of imaginal disc cell size, cell number and organ size by Drosophila class I(A) phosphoinositide 3-kinase and its adaptor. Curr. Biol. 9 1019-29 PubMed GONUTS page
  15. 15.0 15.1 Wu, H et al. () JNK protects Drosophila from oxidative stress by trancriptionally activating autophagy. Mech. Dev. 126 624-37 PubMed GONUTS page
  16. Ugrankar, R et al. (2015) Drosophila glucome screening identifies Ck1alpha as a regulator of mammalian glucose metabolism. Nat Commun 6 7102 PubMed GONUTS page
  17. Oldham, S & Hafen, E (2003) Insulin/IGF and target of rapamycin signaling: a TOR de force in growth control. Trends Cell Biol. 13 79-85 PubMed GONUTS page
  18. 18.0 18.1 18.2 Morrison, DK et al. (2000) Protein kinases and phosphatases in the Drosophila genome. J. Cell Biol. 150 F57-62 PubMed GONUTS page
  19. Wong, JJ et al. (2013) A Cullin1-based SCF E3 ubiquitin ligase targets the InR/PI3K/TOR pathway to regulate neuronal pruning. PLoS Biol. 11 e1001657 PubMed GONUTS page
  20. 20.0 20.1 20.2 MacDougall, LK et al. (2004) Targeted expression of the class II phosphoinositide 3-kinase in Drosophila melanogaster reveals lipid kinase-dependent effects on patterning and interactions with receptor signaling pathways. Mol. Cell. Biol. 24 796-808 PubMed GONUTS page
  21. 21.0 21.1 Bergmann, A & Lane, ME (2003) HIDden targets of microRNAs for growth control. Trends Biochem. Sci. 28 461-3 PubMed GONUTS page
  22. Wu, Q et al. (2005) Regulation of hunger-driven behaviors by neural ribosomal S6 kinase in Drosophila. Proc. Natl. Acad. Sci. U.S.A. 102 13289-94 PubMed GONUTS page
  23. Jia, D et al. (2015) A large-scale in vivo RNAi screen to identify genes involved in Notch-mediated follicle cell differentiation and cell cycle switches. Sci Rep 5 12328 PubMed GONUTS page
  24. Foronda, D et al. (2014) Coordination of insulin and Notch pathway activities by microRNA miR-305 mediates adaptive homeostasis in the intestinal stem cells of the Drosophila gut. Genes Dev. 28 2421-31 PubMed GONUTS page
  25. Hall, DJ et al. (2007) Rheb-TOR signaling promotes protein synthesis, but not glucose or amino acid import, in Drosophila. BMC Biol. 5 10 PubMed GONUTS page
  26. 26.0 26.1 26.2 Oldham, S et al. (2000) Genetic control of size in Drosophila. Philos. Trans. R. Soc. Lond., B, Biol. Sci. 355 945-52 PubMed GONUTS page
  27. Denton, D et al. (2012) Relationship between growth arrest and autophagy in midgut programmed cell death in Drosophila. Cell Death Differ. 19 1299-307 PubMed GONUTS page
  28. Potter, CJ & Xu, T (2001) Mechanisms of size control. Curr. Opin. Genet. Dev. 11 279-86 PubMed GONUTS page
  29. Weinkove, D & Leevers, SJ (2000) The genetic control of organ growth: insights from Drosophila. Curr. Opin. Genet. Dev. 10 75-80 PubMed GONUTS page
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