name: phosphatidylinositol 3-kinase complex, class IA
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def: "A class I phosphatidylinositol 3-kinase complex that possesses 1-phosphatidylinositol-4-phosphate 3-kinase activity; comprises a catalytic class IA phosphoinositide 3-kinase (PI3K) subunit and an associated SH2 domain-containing regulatory subunit that is a member of a family of related proteins often called p85 proteins. Through the interaction with the SH2-containing adaptor subunits, Class IA PI3K catalytic subunits are linked to tyrosine kinase signaling pathways." [PMID:9255069, PMID:9759495]
synonym: "1-phosphatidylinositol-4-phosphate 3-kinase, class IA complex" EXACT 
synonym: "1-phosphatidylinositol-4-phosphate kinase, class IA complex" EXACT 
synonym: "class IA PI3K complex" EXACT 
synonym: "phosphoinositide 3-kinase complex, class IA" EXACT 
is_a: GO:0097651 ! phosphatidylinositol 3-kinase complex, class I
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