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Category:GO:0046934 ! 1-phosphatidylinositol-4,5-bisphosphate 3-kinase activity
name: 1-phosphatidylinositol-4,5-bisphosphate 3-kinase activity
namespace: molecular_function
def: "Catalysis of the reaction: a 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + ATP = a 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate + ADP + H+." [EC:2.7.1.153, RHEA:21292]
synonym: "phosphatidylinositol 3-kinase activity, class I" NARROW []
synonym: "phosphatidylinositol 3-kinase activity, class II" NARROW []
synonym: "phosphatidylinositol 3-kinase, class I, catalyst activity" NARROW []
synonym: "phosphatidylinositol-4,5-bisphosphate 3-kinase activity" EXACT []
synonym: "type I phosphoinositide 3-kinase activity" NARROW [EC:2.7.1.153]
xref: EC:2.7.1.153
xref: KEGG_REACTION:R04545
xref: MetaCyc:2.7.1.153-RXN
xref: RHEA:21292
is_a: GO:0052742 ! phosphatidylinositol kinase activity
AmiGO
<GOterm>GO:0046934</GOterm>
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