GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.

Have any questions? Please email us at ecoliwiki@gmail.com

Category:GO:0048010 ! vascular endothelial growth factor receptor signaling pathway

From GONUTS
Jump to: navigation, search

DAG for GO:0048010id: GO:0048010

name: vascular endothelial growth factor receptor signaling pathway
namespace: biological_process
def: "The series of molecular signals initiated by a ligand binding to a vascular endothelial growth factor receptor (VEGFR) on the surface of the target cell, and ending with the regulation of a downstream cellular process, e.g. transcription." [GOC:ceb, GOC:signaling]
comment: In GO, a gene product with 'vascular endothelial growth factor-activated receptor activity ; GO:0005021' necessarily binds VEGF to transduce a signal. In contrast, the VEGFR refers to PR:000001971. To represent cross-talk between ligands and receptors, signaling pathways in GO are starting to be named after the receptor and/or the signal. GO:0048010 is for annotation of any pathway in which a ligand (VEGF or an alternative growth factor) binds and activates a VEGFR (PR:000001971). For annotation of signaling pathways where a VEGF binds to a cell surface receptor (VEGFR, PDGFR etc.), consider 'vascular endothelial growth factor signaling pathway ; GO:0038084'.
synonym: "VEGF receptor signaling pathway" EXACT []
synonym: "VEGF receptor signalling pathway" EXACT []
synonym: "VEGFR signaling pathway" EXACT []
is_a: GO:0007169 ! cell surface receptor protein tyrosine kinase signaling pathway

AmiGO <GOterm>GO:0048010</GOterm>
Gene Ontology Home


The contents of this box are automatically generated. You can help by adding information to the "Notes"

Usage Notes

References

See Help:References for how to manage references in GONUTS.