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PMID:16182526
| Citation |
Caldwell, PE, Walkiewicz, M and Stern, M (2005) Ras activity in the Drosophila prothoracic gland regulates body size and developmental rate via ecdysone release. Curr. Biol. 15:1785-95 |
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| Abstract |
In Drosophila, each of the three larval instars ends with a molt, triggered by release of steroid molting hormone ecdysone from the prothoracic gland (PG). Because all growth occurs during the larval stages, final body size depends on both the larval growth rate and the duration of each larval stage, which in turn might be regulated by the timing of ecdysone release. |
| Links |
PubMed Online version:10.1016/j.cub.2005.09.011 |
| Keywords |
Animals; Body Size/physiology; Body Weights and Measures; DNA Primers; Drosophila/genetics; Drosophila/growth & development; Drosophila Proteins/metabolism; Ecdysone/biosynthesis; Insulin/metabolism; Larva/growth & development; Microscopy, Fluorescence; Models, Biological; Neuropeptides/metabolism; PTEN Phosphohydrolase/metabolism; Phosphatidylinositol 3-Kinases/metabolism; Polymerase Chain Reaction; Proto-Oncogene Proteins c-raf/metabolism; Signal Transduction/physiology; ras Proteins/metabolism |
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Significance
Annotations
| Gene product | Qualifier | GO ID | GO term name | Evidence Code | with/from | Aspect | Notes | Status |
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See also
References
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