Category:GO:0019005 ! SCF ubiquitin ligase complex

name: SCF ubiquitin ligase complex
namespace: cellular_component
def: "A ubiquitin ligase complex in which a cullin from the Cul1 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a Skp1 adaptor and an F-box protein. SCF complexes are involved in targeting proteins for degradation by the proteasome. The best characterized complexes are those from yeast and mammals (with core subunits named Cdc53/Cul1, Rbx1/Hrt1/Roc1)." [PMID:15571813, PMID:15688063]
synonym: "CDL1 complex" EXACT []
synonym: "CRL1 complex" EXACT []
synonym: "Cul1-RING ubiquitin ligase complex" EXACT []
synonym: "cullin-RING ligase 1" EXACT []
synonym: "SCF complex" EXACT []
synonym: "SCF complex substrate recognition subunit" NARROW []
synonym: "Skp1/Cul1/F-box protein complex" EXACT []
xref: Wikipedia:SCF_complex
is_a: GO:0031461 ! cullin-RING ubiquitin ligase complex

AmiGO <GOterm>GO:0019005</GOterm>
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