HUMAN:FXL12

Species (Taxon ID)	Homo sapiens (Human). (9606)
Gene Name(s)	FBXL12 (synonyms: FBL12)
Protein Name(s)	F-box/LRR-repeat protein 12 F-box and leucine-rich repeat protein 12 F-box protein FBL12
External Links
UniProt	Q9NXK8
EMBL	AK000195 AK027004 AK093760 CH471106 BC001586
CCDS	CCDS12218.1
RefSeq	NP_060173.1 XP_005260021.1 XP_005260022.1 XP_005260023.1 XP_006722845.1
UniGene	Hs.12439
ProteinModelPortal	Q9NXK8
SMR	Q9NXK8
BioGrid	120200
IntAct	Q9NXK8
MINT	MINT-1409594
STRING	9606.ENSP00000247977
PhosphoSite	Q9NXK8
DMDM	38257780
MaxQB	Q9NXK8
PaxDb	Q9NXK8
PeptideAtlas	Q9NXK8
PRIDE	Q9NXK8
DNASU	54850
Ensembl	ENST00000247977 ENST00000585379 ENST00000591009
GeneID	54850
KEGG	hsa:54850
UCSC	uc002mmd.3
CTD	54850
GeneCards	GC19M009920
H-InvDB	HIX0014728 HIX0174428
HGNC	HGNC:13611
HPA	HPA002843
MIM	609079
neXtProt	NX_Q9NXK8
PharmGKB	PA134934043
eggNOG	NOG113187
GeneTree	ENSGT00390000003354
HOGENOM	HOG000112675
HOVERGEN	HBG051672
InParanoid	Q9NXK8
KO	K10278
OMA	ISMAWLL
PhylomeDB	Q9NXK8
TreeFam	TF313434
UniPathway	UPA00143
GenomeRNAi	54850
NextBio	57696
PRO	PR:Q9NXK8
Proteomes	UP000005640
Bgee	Q9NXK8
CleanEx	HS_FBXL12
ExpressionAtlas	Q9NXK8
Genevestigator	Q9NXK8
GO	GO:0005737 GO:0000151 GO:0016567 GO:0006511
InterPro	IPR001810
Pfam	PF12937
SMART	SM00256
SUPFAM	SSF81383
PROSITE	PS50181

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
contributes_to	GO:0061630	ubiquitin protein ligase activity		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1351663 PANTHER:PTN001923412	F		Seeded From UniProt	complete
involved_in	GO:0051726	regulation of cell cycle		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1351663 PANTHER:PTN002364414	P		Seeded From UniProt	complete
involved_in	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1354702 PANTHER:PTN001923412 PomBase:SPCC338.16 SGD:S000005606 TAIR:locus:2061136 UniProtKB:Q9UKT7	P		Seeded From UniProt	complete
part_of	GO:0019005	SCF ubiquitin ligase complex		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0037236 MGI:MGI:1351663 MGI:MGI:2442921 PANTHER:PTN001923412 RGD:1311830 SGD:S000005606 TAIR:locus:2099237 TAIR:locus:2174398 UniProtKB:Q13309 UniProtKB:Q9UKT7	C		Seeded From UniProt	complete
part_of	GO:0005829	cytosol		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN002364414 UniProtKB:Q13309	C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN002364414 UniProtKB:Q13309	C		Seeded From UniProt	complete
involved_in	GO:0000086	G2/M transition of mitotic cell cycle		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1351663 PANTHER:PTN002364414	P		Seeded From UniProt	complete
involved_in	GO:0006511	ubiquitin-dependent protein catabolic process	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9EPX5 ensembl:ENSMUSP00000119124	P		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9EPX5 ensembl:ENSMUSP00000119124	C		Seeded From UniProt	complete
part_of	GO:0000151	ubiquitin ligase complex	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9EPX5 ensembl:ENSMUSP00000119124	C		Seeded From UniProt	complete
involved_in	GO:0043687	post-translational protein modification	Reactome:R-HSA-597592	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005829	cytosol	Reactome:R-HSA-983157 Reactome:R-HSA-983156 Reactome:R-HSA-983147 Reactome:R-HSA-983140 Reactome:R-HSA-8956200 Reactome:R-HSA-8956040 Reactome:R-HSA-8955289 Reactome:R-HSA-8955241 Reactome:R-HSA-8952620 Reactome:R-HSA-8952618	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0000209	protein polyubiquitination	Reactome:R-HSA-983168	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0016567	protein ubiquitination	GO_REF:0000041	ECO:0000322	imported manually asserted information used in automatic assertion	UniPathway:UPA00143	P		Seeded From UniProt	complete
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References

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