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YEAST:SAF1

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Species (Taxon ID) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). (559292)
Gene Name(s) SAF1
Protein Name(s) SCF-associated factor 1
External Links
UniProt P38352
EMBL X76053
Z36149
BK006936
PIR S44542
RefSeq NP_009839.4
ProteinModelPortal P38352
BioGrid 32974
DIP DIP-6307N
IntAct P38352
MINT MINT-687968
STRING 4932.YBR280C
MaxQB P38352
PaxDb P38352
EnsemblFungi [example_ID YBR280C]
GeneID 852583
KEGG sce:YBR280C
CYGD YBR280c
SGD S000000484
eggNOG NOG75720
HOGENOM HOG000000739
InParanoid P38352
KO K15072
OMA GGFSFQI
OrthoDB EOG7BCNNW
BioCyc YEAST:G3O-29200-MONOMER
UniPathway UPA00143
NextBio 971730
Proteomes UP000002311
Genevestigator P38352
GO GO:0019005
GO:0016567
GO:0031146
Gene3D 2.130.10.30
InterPro IPR001810
IPR009091
IPR000408
IPR027046
PANTHER PTHR22870:SF120
SUPFAM SSF50985
SSF81383
PROSITE PS00626
PS50012

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0031146

SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

PMID:16677311[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0031146

SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

PMID:17517885[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0031146

SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

PMID:17517885[2]

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P07834

P

Seeded From UniProt

complete

part_of

GO:0019005

SCF ubiquitin ligase complex

PMID:17517885[2]

ECO:0000353

physical interaction evidence used in manual assertion

SGD:S000002736

C

Seeded From UniProt

complete

part_of

GO:0019005

SCF ubiquitin ligase complex

PMID:17517885[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0019005

SCF ubiquitin ligase complex

PMID:11283612[3]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0019005

SCF ubiquitin ligase complex

PMID:19882662[4]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0019005

SCF ubiquitin ligase complex

PMID:17517885[2]

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P07834

C

Seeded From UniProt

complete

contributes_to

GO:0004842

ubiquitin-protein transferase activity

PMID:17517885[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

F

Seeded From UniProt

complete

contributes_to

GO:0004842

ubiquitin-protein transferase activity

PMID:17517885[2]

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P07834

F

Seeded From UniProt

complete

involved_in

GO:0016567

protein ubiquitination

GO_REF:0000041

ECO:0000322

imported manually asserted information used in automatic assertion

UniPathway:UPA00143

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Escusa, S et al. (2006) Proteasome- and SCF-dependent degradation of yeast adenine deaminase upon transition from proliferation to quiescence requires a new F-box protein named Saf1p. Mol. Microbiol. 60 1014-25 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 2.5 2.6 Escusa, S et al. (2007) Skp1-Cullin-F-box-dependent degradation of Aah1p requires its interaction with the F-box protein Saf1p. J. Biol. Chem. 282 20097-103 PubMed GONUTS page
  3. Seol, JH et al. (2001) Skp1 forms multiple protein complexes, including RAVE, a regulator of V-ATPase assembly. Nat. Cell Biol. 3 384-91 PubMed GONUTS page
  4. Kato, M et al. (2010) Remodeling of the SCF complex-mediated ubiquitination system by compositional alteration of incorporated F-box proteins. Proteomics 10 115-23 PubMed GONUTS page