GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.

Have any questions? Please email us at ecoliwiki@gmail.com

HUMAN:FXL19

From GONUTS
Jump to: navigation, search
Species (Taxon ID) Homo sapiens (Human). (9606)
Gene Name(s) FBXL19 (synonyms: FBL19)
Protein Name(s) F-box/LRR-repeat protein 19

F-box and leucine-rich repeat protein 19

External Links
UniProt Q6PCT2
EMBL AC135048
BC059173
AK098777
AL137589
CCDS CCDS45465.1
PIR T46301
RefSeq NP_001093254.2
NP_001269280.1
UniGene Hs.152149
ProteinModelPortal Q6PCT2
SMR Q6PCT2
BioGrid 120078
STRING 9606.ENSP00000369666
PhosphoSite Q6PCT2
DMDM 322510127
MaxQB Q6PCT2
PaxDb Q6PCT2
PRIDE Q6PCT2
Ensembl ENST00000380310
GeneID 54620
KEGG hsa:54620
UCSC uc002dzz.1
uc002eaa.2
CTD 54620
GeneCards GC16P030934
H-InvDB HIX0020867
HGNC HGNC:25300
HPA HPA035317
MIM 609085
neXtProt NX_Q6PCT2
PharmGKB PA134911396
eggNOG NOG305609
GeneTree ENSGT00550000074396
HOGENOM HOG000112677
HOVERGEN HBG061227
InParanoid Q6PCT2
KO K10285
OMA SSCHPGL
OrthoDB EOG7GQXV8
PhylomeDB Q6PCT2
TreeFam TF338452
ChiTaRS FBXL19
GenomeRNAi 54620
NextBio 57145
PRO PR:Q6PCT2
Proteomes UP000005640
Bgee Q6PCT2
ExpressionAtlas Q6PCT2
Genevestigator Q6PCT2
GO GO:0019005
GO:0003677
GO:0008270
GO:0043161
Gene3D 3.30.40.10
InterPro IPR001810
IPR019786
IPR002857
IPR011011
IPR001965
IPR019787
IPR013083
Pfam PF00646
PF02008
SMART SM00256
SM00249
SUPFAM SSF57903
PROSITE PS51058
PS01359
PS50016

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0043161

proteasome-mediated ubiquitin-dependent protein catabolic process

PMID:22660580[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0019005

SCF ubiquitin ligase complex

PMID:22660580[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0043161

proteasome-mediated ubiquitin-dependent protein catabolic process

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q6PB97
ensembl:ENSMUSP00000033081

P

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002857

F

Seeded From UniProt

complete

enables

GO:0008270

zinc ion binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002857

F

Seeded From UniProt

complete

involved_in

GO:0043687

post-translational protein modification

Reactome:R-HSA-597592

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

Reactome:R-HSA-983157
Reactome:R-HSA-983156
Reactome:R-HSA-983147
Reactome:R-HSA-983140
Reactome:R-HSA-8956200
Reactome:R-HSA-8956040
Reactome:R-HSA-8955289
Reactome:R-HSA-8955241
Reactome:R-HSA-8952620
Reactome:R-HSA-8952618

ECO:0000304

author statement supported by traceable reference used in manual assertion










C

Seeded From UniProt

complete

involved_in

GO:0000209

protein polyubiquitination

Reactome:R-HSA-983168

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Zhao, J et al. (2012) F-box protein FBXL19-mediated ubiquitination and degradation of the receptor for IL-33 limits pulmonary inflammation. Nat. Immunol. 13 651-8 PubMed GONUTS page