Category:GO:0007186 ! G protein-coupled receptor signaling pathway

name: G protein-coupled receptor signaling pathway
namespace: biological_process
alt_id: GO:0038042
def: "The series of molecular signals initiated by a ligand binding to its receptor, in which the activated receptor promotes the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, and ends with regulation of a downstream cellular process. The pathway can start from the plasma membrane, Golgi or nuclear membrane." [GOC:bf, GOC:mah, PMID:16902576, PMID:24568158, Wikipedia:G_protein-coupled_receptor]
subset: goslim_drosophila
synonym: "dimeric G-protein coupled receptor signaling pathway" NARROW []
synonym: "dimeric G-protein coupled receptor signalling pathway" NARROW [GOC:mah]
synonym: "G protein coupled receptor protein signaling pathway" EXACT []
synonym: "G protein coupled receptor protein signalling pathway" EXACT []
synonym: "G-protein coupled receptor protein signal transduction" EXACT []
synonym: "G-protein coupled receptor protein signaling pathway" EXACT [GOC:bf]
synonym: "G-protein coupled receptor signaling pathway via GPCR dimer" NARROW [GOC:bf]
synonym: "G-protein coupled receptor signalling pathway" EXACT []
synonym: "G-protein-coupled receptor protein signalling pathway" EXACT []
synonym: "GPCR signaling pathway" EXACT []
synonym: "GPCR signalling pathway" EXACT []
is_a: GO:0007165 ! signal transduction
relationship: has_part: GO:0004930 ! G protein-coupled receptor activity

AmiGO <GOterm>GO:0007186</GOterm>
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