CHICK:GNAI1

Species (Taxon ID)	Gallus gallus (Chicken). (9031)
Gene Name(s)	GNAI1
Protein Name(s)	Guanine nucleotide-binding protein G(i) subunit alpha-1 Adenylate cyclase-inhibiting G alpha protein
External Links
UniProt	P50146
EMBL	L24548
PIR	I50237
RefSeq	NP_990734.1
UniGene	Gga.18910
ProteinModelPortal	P50146
SMR	P50146
STRING	9031.ENSGALP00000013640
PaxDb	P50146
PRIDE	P50146
GeneID	396368
KEGG	gga:396368
CTD	2770
eggNOG	NOG322962
HOGENOM	HOG000038730
HOVERGEN	HBG063184
InParanoid	P50146
KO	K04630
PhylomeDB	P50146
NextBio	20816413
PRO	PR:P50146
Proteomes	UP000000539
GO	GO:0005813 GO:0005737 GO:0030496 GO:0005634 GO:0005886 GO:0005525 GO:0003924 GO:0046872 GO:0004871 GO:0007188 GO:0007049 GO:0051301 GO:0007186 GO:0050805
Gene3D	1.10.400.10 3.40.50.300
InterPro	IPR001408 IPR001019 IPR011025 IPR027417
PANTHER	PTHR10218
Pfam	PF00503
PRINTS	PR00318 PR00441
SMART	SM00275
SUPFAM	SSF47895 SSF52540

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Notes	Status
part_of	GO:0099738	cell cortex region	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P63096	C	Seeded From UniProt	complete
involved_in	GO:1904778	positive regulation of protein localization to cell cortex	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P63096	P	Seeded From UniProt	complete
involved_in	GO:0060236	regulation of mitotic spindle organization	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P63096	P	Seeded From UniProt	complete
enables	GO:0019003	GDP binding	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P10824	F	Seeded From UniProt	complete
enables	GO:0005525	GTP binding	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P10824	F	Seeded From UniProt	complete
enables	GO:0003924	GTPase activity	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P10824	F	Seeded From UniProt	complete
enables	GO:0001664	G protein-coupled receptor binding	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P10824	F	Seeded From UniProt	complete
enables	GO:0000287	magnesium ion binding	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P10824	F	Seeded From UniProt	complete
involved_in	GO:1904322	cellular response to forskolin	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P10824	P	Seeded From UniProt	complete
involved_in	GO:0043949	regulation of cAMP-mediated signaling	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P10824	P	Seeded From UniProt	complete
involved_in	GO:0050805	negative regulation of synaptic transmission	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P10824	P	Seeded From UniProt	complete
involved_in	GO:0007186	G protein-coupled receptor signaling pathway	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P10824	P	Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P63096	C	Seeded From UniProt	complete
involved_in	GO:0051301	cell division	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P63096	P	Seeded From UniProt	complete
part_of	GO:0030496	midbody	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P63096	C	Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P10824	C	Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P63096	C	Seeded From UniProt	complete
part_of	GO:0005813	centrosome	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P10824	C	Seeded From UniProt	complete
part_of	GO:0005813	centrosome	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P63096	C	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P10824	C	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P63096	C	Seeded From UniProt	complete
enables	GO:0031821	G protein-coupled serotonin receptor binding	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000741500 RGD:2713	F	Seeded From UniProt	complete
enables	GO:0031683	G-protein beta/gamma-subunit complex binding	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:95778 PANTHER:PTN000026392	F	Seeded From UniProt	complete
involved_in	GO:0007188	adenylate cyclase-modulating G protein-coupled receptor signaling pathway	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:95768 PANTHER:PTN000026392 RGD:2717 dictyBase:DDB_G0276267	P	Seeded From UniProt	complete
part_of	GO:0005834	heterotrimeric G-protein complex	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0001122 FB:FBgn0001123 MGI:MGI:3588268 PANTHER:PTN000026392 PomBase:SPAC23H3.13c RGD:1304683 RGD:2716 SGD:S000001047 TAIR:locus:2005529 dictyBase:DDB_G0276267	C	Seeded From UniProt	complete
enables	GO:0003924	GTPase activity	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0004435 MGI:MGI:3588268 MGI:MGI:95775 MGI:MGI:95778 PANTHER:PTN000026392 PomBase:SPBC24C6.06 RGD:2713 RGD:628732 RGD:727817 SGD:S000000822 SGD:S000001047 TAIR:locus:2005529 TAIR:locus:2034446 TAIR:locus:2046738 TAIR:locus:2116204 UniProtKB:P08754 UniProtKB:Q00743 WB:WBGene00001648 dictyBase:DDB_G0276267 dictyBase:DDB_G0283349	F	Seeded From UniProt	complete
enables	GO:0001664	G protein-coupled receptor binding	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:95770 PANTHER:PTN000026392 RGD:2713 UniProtKB:P04695 UniProtKB:P30679 dictyBase:DDB_G0276267	F	Seeded From UniProt	complete
enables	GO:0003924	GTPase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001019 InterPro:IPR001408	F	Seeded From UniProt	complete
enables	GO:0005525	GTP binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001408	F	Seeded From UniProt	complete
involved_in	GO:0007165	signal transduction	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR011025	P	Seeded From UniProt	complete
involved_in	GO:0007186	G protein-coupled receptor signaling pathway	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001019 InterPro:IPR001408	P	Seeded From UniProt	complete
involved_in	GO:0007188	adenylate cyclase-modulating G protein-coupled receptor signaling pathway	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001408	P	Seeded From UniProt	complete
enables	GO:0019001	guanyl nucleotide binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001019	F	Seeded From UniProt	complete
enables	GO:0031683	G-protein beta/gamma-subunit complex binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001019 InterPro:IPR001408	F	Seeded From UniProt	complete
involved_in	GO:0007165	signal transduction	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0807	P	Seeded From UniProt	complete
part_of	GO:0005856	cytoskeleton	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0206	C	Seeded From UniProt	complete
enables	GO:0000166	nucleotide binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0547	F	Seeded From UniProt	complete
enables	GO:0005525	GTP binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0342	F	Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0472 UniProtKB-SubCell:SL-0162	C	Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-1003 UniProtKB-SubCell:SL-0039	C	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0963 UniProtKB-SubCell:SL-0086	C	Seeded From UniProt	complete
enables	GO:0046872	metal ion binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0479	F	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0539 UniProtKB-SubCell:SL-0191	C	Seeded From UniProt	complete
involved_in	GO:0007049	cell cycle	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0131	P	Seeded From UniProt	complete
involved_in	GO:0051301	cell division	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0132	P	Seeded From UniProt	complete
part_of	GO:0005938	cell cortex	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0138	C	Seeded From UniProt	complete
part_of	GO:0005815	microtubule organizing center	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0048	C	Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 ^1.2 ^1.3 ^1.4 ^1.5 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:21873635-1] 1.0 ^1.1 ^1.2 ^1.3 ^1.4 ^1.5 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

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CHICK:GNAI1

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