Category:GO:0005834 ! heterotrimeric G-protein complex

name: heterotrimeric G-protein complex
namespace: cellular_component
def: "Any of a family of heterotrimeric GTP-binding and hydrolyzing proteins; they belong to a superfamily of GTPases that includes monomeric proteins such as EF-Tu and RAS. Heterotrimeric G-proteins consist of three subunits; the alpha subunit contains the guanine nucleotide binding site and possesses GTPase activity; the beta and gamma subunits are tightly associated and function as a beta-gamma heterodimer; extrinsic plasma membrane proteins (cytoplasmic face) that function as a complex to transduce signals from G protein-coupled receptors to an effector protein." [ISBN:0198547684]
comment: See also the molecular function term 'G protein-coupled receptor activity ; GO:0004930'.
synonym: "heterotrimeric G-protein GTPase activity" RELATED []
synonym: "heterotrimeric G-protein GTPase, alpha-subunit" NARROW []
synonym: "heterotrimeric G-protein GTPase, beta-subunit" NARROW []
synonym: "heterotrimeric G-protein GTPase, gamma-subunit" NARROW []
is_a: GO:0098797 ! plasma membrane protein complex
is_a: GO:1905360 ! GTPase complex
relationship: part_of: GO:0031234 ! extrinsic component of cytoplasmic side of plasma membrane

AmiGO <GOterm>GO:0005834</GOterm>
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