GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.

Have any questions? Please email us at ecoliwiki@gmail.com

DROME:GNAF

From GONUTS
Jump to: navigation, search
Species (Taxon ID) Drosophila melanogaster (Fruit fly). (7227)
Gene Name(s) Galphaf (synonyms: G-A73B, Galpha73B)
Protein Name(s) Guanine nucleotide-binding protein G(f) subunit alpha

G protein alpha f subunit

External Links
UniProt Q05337
EMBL L09700
AE014296
BT064643
PIR A47460
RefSeq NP_524118.1
UniGene Dm.2534
ProteinModelPortal Q05337
SMR Q05337
IntAct Q05337
STRING 7227.FBpp0075113
PRIDE Q05337
EnsemblMetazoa FBtr0075354
GeneID 39861
KEGG dme:Dmel_CG12232
CTD 39861
FlyBase FBgn0010223
eggNOG NOG319154
GeneTree ENSGT00770000120503
InParanoid Q05337
KO K04640
OMA ERECYYH
OrthoDB EOG7M3J09
PhylomeDB Q05337
Reactome REACT_212409
REACT_221889
REACT_248371
REACT_255277
REACT_259532
GenomeRNAi 39861
NextBio 815754
Proteomes UP000000803
Bgee Q05337
GO GO:0031683
GO:0001664
GO:0005525
GO:0003924
GO:0046872
GO:0004871
GO:0007191
GO:0007498
GO:0035208
GO:0051489
GO:0007606
Gene3D 1.10.400.10
3.40.50.300
InterPro IPR001019
IPR011025
IPR027417
PANTHER PTHR10218
Pfam PF00503
PRINTS PR00318
SMART SM00275
SUPFAM SSF47895
SSF52540

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

enables

GO:0031683

G-protein beta/gamma-subunit complex binding

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:95778
PANTHER:PTN000026392

F

Seeded From UniProt

complete

involved_in

GO:0007188

adenylate cyclase-modulating G protein-coupled receptor signaling pathway

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:95768
PANTHER:PTN000026392
RGD:2717
dictyBase:DDB_G0276267

P

Seeded From UniProt

complete

part_of

GO:0005834

heterotrimeric G-protein complex

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0001122
FB:FBgn0001123
MGI:MGI:3588268
PANTHER:PTN000026392
PomBase:SPAC23H3.13c
RGD:1304683
RGD:2716
SGD:S000001047
TAIR:locus:2005529
dictyBase:DDB_G0276267

C

Seeded From UniProt

complete

enables

GO:0003924

GTPase activity

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0004435
MGI:MGI:3588268
MGI:MGI:95775
MGI:MGI:95778
PANTHER:PTN000026392
PomBase:SPBC24C6.06
RGD:2713
RGD:628732
RGD:727817
SGD:S000000822
SGD:S000001047
TAIR:locus:2005529
TAIR:locus:2034446
TAIR:locus:2046738
TAIR:locus:2116204
UniProtKB:P08754
UniProtKB:Q00743
WB:WBGene00001648
dictyBase:DDB_G0276267
dictyBase:DDB_G0283349

F

Seeded From UniProt

complete

enables

GO:0001664

G protein-coupled receptor binding

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:95770
PANTHER:PTN000026392
RGD:2713
UniProtKB:P04695
UniProtKB:P30679
dictyBase:DDB_G0276267

F

Seeded From UniProt

complete

involved_in

GO:0051489

regulation of filopodium assembly

PMID:24163435[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0035208

positive regulation of hemocyte proliferation

PMID:20168330[3]

ECO:0000316

genetic interaction evidence used in manual assertion

FB:FBgn0004864

P

Seeded From UniProt

complete

involved_in

GO:0007498

mesoderm development

PMID:11486054[4]

ECO:0000270

expression pattern evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0003924

GTPase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001019

F

Seeded From UniProt

complete

involved_in

GO:0007165

signal transduction

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR011025

P

Seeded From UniProt

complete

involved_in

GO:0007186

G protein-coupled receptor signaling pathway

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001019

P

Seeded From UniProt

complete

enables

GO:0019001

guanyl nucleotide binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001019

F

Seeded From UniProt

complete

enables

GO:0031683

G-protein beta/gamma-subunit complex binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001019

F

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

involved_in

GO:0007165

signal transduction

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0807

P

Seeded From UniProt

complete

enables

GO:0000166

nucleotide binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0547

F

Seeded From UniProt

complete

enables

GO:0005525

GTP binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0342

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 1.4 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
  2. Bausek, N & Zeidler, MP (2014) Gα73B is a downstream effector of JAK/STAT signalling and a regulator of Rho1 in Drosophila haematopoiesis. J. Cell. Sci. 127 101-10 PubMed GONUTS page
  3. Bina, S et al. (2010) Transcriptional targets of Drosophila JAK/STAT pathway signalling as effectors of haematopoietic tumour formation. EMBO Rep. 11 201-7 PubMed GONUTS page
  4. Furlong, EE et al. (2001) Patterns of gene expression during Drosophila mesoderm development. Science 293 1629-33 PubMed GONUTS page