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DROME:GNAF

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Species (Taxon ID) Drosophila melanogaster (Fruit fly). (7227)
Gene Name(s) Galphaf (synonyms: G-A73B, Galpha73B)
Protein Name(s) Guanine nucleotide-binding protein G(f) subunit alpha

G protein alpha f subunit

External Links
UniProt Q05337
EMBL L09700
AE014296
BT064643
PIR A47460
RefSeq NP_524118.1
UniGene Dm.2534
ProteinModelPortal Q05337
SMR Q05337
IntAct Q05337
STRING 7227.FBpp0075113
PRIDE Q05337
EnsemblMetazoa FBtr0075354
GeneID 39861
KEGG dme:Dmel_CG12232
CTD 39861
FlyBase FBgn0010223
eggNOG NOG319154
GeneTree ENSGT00770000120503
InParanoid Q05337
KO K04640
OMA ERECYYH
OrthoDB EOG7M3J09
PhylomeDB Q05337
Reactome REACT_212409
REACT_221889
REACT_248371
REACT_255277
REACT_259532
GenomeRNAi 39861
NextBio 815754
Proteomes UP000000803
Bgee Q05337
GO GO:0031683
GO:0001664
GO:0005525
GO:0003924
GO:0046872
GO:0004871
GO:0007191
GO:0007498
GO:0035208
GO:0051489
GO:0007606
Gene3D 1.10.400.10
3.40.50.300
InterPro IPR001019
IPR011025
IPR027417
PANTHER PTHR10218
Pfam PF00503
PRINTS PR00318
SMART SM00275
SUPFAM SSF47895
SSF52540

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000166

nucleotide binding

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0547

F

Seeded From UniProt

complete

GO:0001664

G-protein coupled receptor binding

GO_REF:0000033

IBA: Inferred from Biological aspect of Ancestor

PANTHER:PTN000026392

F

Seeded From UniProt

complete

GO:0003924

GTPase activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001019

F

Seeded From UniProt

complete

GO:0003924

GTPase activity

GO_REF:0000033

IBA: Inferred from Biological aspect of Ancestor

PANTHER:PTN000026392

F

Seeded From UniProt

complete

GO:0004871

signal transducer activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001019
InterPro:IPR011025

F

Seeded From UniProt

complete

GO:0004871

signal transducer activity

GO_REF:0000033

IBA: Inferred from Biological aspect of Ancestor

PANTHER:PTN000026392

F

Seeded From UniProt

complete

GO:0004871

signal transducer activity

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0807

F

Seeded From UniProt

complete

GO:0005525

GTP binding

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0342

F

Seeded From UniProt

complete

GO:0005834

heterotrimeric G-protein complex

GO_REF:0000033

IBA: Inferred from Biological aspect of Ancestor

PANTHER:PTN000026392

C

Seeded From UniProt

complete

GO:0007165

signal transduction

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR011025

P

Seeded From UniProt

complete

GO:0007165

signal transduction

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0807

P

Seeded From UniProt

complete

GO:0007186

G-protein coupled receptor signaling pathway

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001019

P

Seeded From UniProt

complete

GO:0007191

adenylate cyclase-activating dopamine receptor signaling pathway

GO_REF:0000033

IBA: Inferred from Biological aspect of Ancestor

PANTHER:PTN000026754

P

Seeded From UniProt

complete

GO:0007498

mesoderm development

PMID:11486054[1]

IEP: Inferred from Expression Pattern

P

Seeded From UniProt

complete

GO:0007606

sensory perception of chemical stimulus

GO_REF:0000033

IBA: Inferred from Biological aspect of Ancestor

PANTHER:PTN000026754

P

Seeded From UniProt

complete

GO:0008152

metabolic process

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001019

P

Seeded From UniProt

complete

GO:0019001

guanyl nucleotide binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001019

F

Seeded From UniProt

complete

GO:0031683

G-protein beta/gamma-subunit complex binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001019

F

Seeded From UniProt

complete

GO:0031683

G-protein beta/gamma-subunit complex binding

GO_REF:0000033

IBA: Inferred from Biological aspect of Ancestor

PANTHER:PTN000026392

F

Seeded From UniProt

complete

GO:0035208

positive regulation of hemocyte proliferation

PMID:20168330[2]

IGI: Inferred from Genetic Interaction

FB:FBgn0004864

P

Seeded From UniProt

complete

GO:0046872

metal ion binding

GO_REF:0000037

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

GO:0051489

regulation of filopodium assembly

PMID:24163435[3]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Furlong, EE et al. (2001) Patterns of gene expression during Drosophila mesoderm development. Science 293 1629-33 PubMed GONUTS page
  2. Bina, S et al. (2010) Transcriptional targets of Drosophila JAK/STAT pathway signalling as effectors of haematopoietic tumour formation. EMBO Rep. 11 201-7 PubMed GONUTS page
  3. Bausek, N & Zeidler, MP (2014) Gα73B is a downstream effector of JAK/STAT signalling and a regulator of Rho1 in Drosophila haematopoiesis. J. Cell. Sci. 127 101-10 PubMed GONUTS page