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CAEEL:Q18534

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Species (Taxon ID) Caenorhabditis elegans. (6239)
Gene Name(s) No Information Provided.
Protein Name(s) Protein NPR-1 (ECO:0000313 with EMBL:CCD67081.1)
External Links
UniProt Q18534
EMBL FO080826
PIR T29741
RefSeq NP_508816.1
UniGene Cel.621
ProteinModelPortal Q18534
SMR Q18534
STRING 6239.C39E6.6
PaxDb Q18534
PRIDE Q18534
EnsemblMetazoa C39E6.6
GeneID 180752
KEGG cel:CELE_C39E6.6
UCSC C39E6.6
CTD 180752
WormBase C39E6.6
eggNOG NOG149782
GeneTree ENSGT00760000118781
HOGENOM HOG000020311
InParanoid Q18534
OMA LESSCAF
OrthoDB EOG7RFTHZ
PhylomeDB Q18534
NextBio 910772
PRO PR:Q18534
Proteomes UP000001940
GO GO:0030424
GO:0030425
GO:0005887
GO:0043025
GO:0008188
GO:0004983
GO:0007631
GO:0007218
GO:0045471
GO:0070482
InterPro IPR000276
IPR017452
IPR000611
Pfam PF00001
PRINTS PR00237
PR01012
PROSITE PS00237
PS50262

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0043052

thermotaxis

PMID:21368276[1]

IMP: Inferred from Mutant Phenotype

P

Fig 6 or 7

complete
CACAO 7305

GO:0004871

signal transducer activity

GO_REF:0000038

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0807

F

Seeded From UniProt

complete

GO:0004930

G-protein coupled receptor activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000276

F

Seeded From UniProt

complete

GO:0004930

G-protein coupled receptor activity

GO_REF:0000038

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0297

F

Seeded From UniProt

complete

GO:0004983

neuropeptide Y receptor activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000611

F

Seeded From UniProt

complete

GO:0005887

integral component of plasma membrane

GO_REF:0000033

IBA: Inferred from Biological aspect of Ancestor

PANTHER:PTN001544342

C

Seeded From UniProt

complete

GO:0005887

integral component of plasma membrane

PMID:14555955[2]

IC: Inferred by Curator

GO:0008188

C

Seeded From UniProt

complete

GO:0007165

signal transduction

GO_REF:0000038

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0807

P

Seeded From UniProt

complete

GO:0007186

G-protein coupled receptor signaling pathway

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000276
InterPro:IPR000611

P

Seeded From UniProt

complete

GO:0007186

G-protein coupled receptor signaling pathway

GO_REF:0000038

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0297

P

Seeded From UniProt

complete

GO:0007218

neuropeptide signaling pathway

PMID:12821653[3]

IDA: Inferred from Direct Assay

P

Seeded From UniProt

complete

GO:0007218

neuropeptide signaling pathway

PMID:14555955[2]

IDA: Inferred from Direct Assay

P

Seeded From UniProt

complete

GO:0007631

feeding behavior

PMID:14555955[2]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0007631

feeding behavior

PMID:15220933[4]

IMP: Inferred from Mutant Phenotype

WB:WBVar00000046
WB:WBVar00145397

P

Seeded From UniProt

complete

GO:0008188

neuropeptide receptor activity

PMID:12821653[3]

IDA: Inferred from Direct Assay

F

Seeded From UniProt

complete

GO:0008188

neuropeptide receptor activity

PMID:14555955[2]

IDA: Inferred from Direct Assay

F

Seeded From UniProt

complete

GO:0016021

integral component of membrane

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000276
InterPro:IPR000611
InterPro:IPR017452

C

Seeded From UniProt

complete

GO:0016021

integral component of membrane

GO_REF:0000038

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

GO:0030424

axon

PMID:12410311[5]

IDA: Inferred from Direct Assay

C

Seeded From UniProt

complete

GO:0030425

dendrite

PMID:12410311[5]

IDA: Inferred from Direct Assay

C

Seeded From UniProt

complete

GO:0043025

neuronal cell body

PMID:12410311[5]

IDA: Inferred from Direct Assay

C

Seeded From UniProt

complete

GO:0043052

thermotaxis

PMID:21368276[1]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0045471

response to ethanol

PMID:15182714[6]

IMP: Inferred from Mutant Phenotype

WB:WBVar00000046
WB:WBVar00088388
WB:WBVar00090144

P

Seeded From UniProt

complete

GO:0070482

response to oxygen levels

PMID:15220933[4]

IMP: Inferred from Mutant Phenotype

WB:WBVar00000046
WB:WBVar00145397

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Glauser, DA et al. (2011) Heat avoidance is regulated by transient receptor potential (TRP) channels and a neuropeptide signaling pathway in Caenorhabditis elegans. Genetics 188 91-103 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 Rogers, C et al. (2003) Inhibition of Caenorhabditis elegans social feeding by FMRFamide-related peptide activation of NPR-1. Nat. Neurosci. 6 1178-85 PubMed GONUTS page
  3. 3.0 3.1 Kubiak, TM et al. (2003) Differential activation of "social" and "solitary" variants of the Caenorhabditis elegans G protein-coupled receptor NPR-1 by its cognate ligand AF9. J. Biol. Chem. 278 33724-9 PubMed GONUTS page
  4. 4.0 4.1 Gray, JM et al. (2004) Oxygen sensation and social feeding mediated by a C. elegans guanylate cyclase homologue. Nature 430 317-22 PubMed GONUTS page
  5. 5.0 5.1 5.2 Coates, JC & de Bono, M (2002) Antagonistic pathways in neurons exposed to body fluid regulate social feeding in Caenorhabditis elegans. Nature 419 925-9 PubMed GONUTS page
  6. Davies, AG et al. (2004) Natural variation in the npr-1 gene modifies ethanol responses of wild strains of C. elegans. Neuron 42 731-43 PubMed GONUTS page