BOVIN:RAC2

Species (Taxon ID)	Bos taurus (Bovine). (9913)
Gene Name(s)	RAC2
Protein Name(s)	Ras-related C3 botulinum toxin substrate 2 p21-Rac2
External Links
UniProt	Q9TU25
EMBL	AF175263 BC102255
RefSeq	NP_786986.1
UniGene	Bt.4946
ProteinModelPortal	Q9TU25
SMR	Q9TU25
STRING	9913.ENSBTAP00000014666
PaxDb	Q9TU25
PRIDE	Q9TU25
Ensembl	ENSBTAT00000014666
GeneID	327671
KEGG	bta:327671
CTD	5880
eggNOG	KOG0393 COG1100
GeneTree	ENSGT00760000118978
HOGENOM	HOG000233974
HOVERGEN	HBG009351
InParanoid	Q9TU25
KO	K07860
OMA	MVELRWQ
OrthoDB	EOG764747
TreeFam	TF101109
Reactome	R-BTA-114604 R-BTA-194840 R-BTA-416482 R-BTA-416572 R-BTA-5668599
NextBio	20810136
Proteomes	UP000009136
ExpressionAtlas	Q9TU25
GO	GO:0005884 GO:0005737 GO:0070062 GO:0005925 GO:0030027 GO:0016020 GO:0005635 GO:0005525 GO:0019887 GO:0007015 GO:0030031 GO:0006935 GO:0007186 GO:0071593 GO:0008284 GO:0010592 GO:0090023 GO:1903955 GO:0010810 GO:0060753 GO:0043304 GO:0060263 GO:0042129 GO:0007264
Gene3D	3.40.50.300
InterPro	IPR027417 IPR005225 IPR001806 IPR003578
Pfam	PF00071
SMART	SM00174
SUPFAM	SSF52540
TIGRFAMs	TIGR00231
PROSITE	PS51420

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Notes	Status
involved_in	GO:1902622	regulation of neutrophil migration	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:97845 MGI:MGI:97846 PANTHER:PTN002374567 UniProtKB:P15153 UniProtKB:P63000 ZFIN:ZDB-GENE-040625-27	P	Seeded From UniProt	complete
part_of	GO:0042995	cell projection	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0010333 MGI:MGI:97845 PANTHER:PTN002784637 RGD:619755 UniProtKB:P15153 UniProtKB:P63000 WB:WBGene00004287	C	Seeded From UniProt	complete
part_of	GO:0031410	cytoplasmic vesicle	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:97845 PANTHER:PTN002784637 RGD:619755 UniProtKB:P63000 WB:WBGene00000424 dictyBase:DDB_G0293526	C	Seeded From UniProt	complete
involved_in	GO:0030036	actin cytoskeleton organization	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0010333 FB:FBgn0014011 MGI:MGI:97845 MGI:MGI:97846 PANTHER:PTN002784637 RGD:1307568 RGD:619755 UniProtKB:P15153 UniProtKB:P63000 UniProtKB:Q6LC82 WB:WBGene00004287	P	Seeded From UniProt	complete
involved_in	GO:0030031	cell projection assembly	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:97846 PANTHER:PTN002374567	P	Seeded From UniProt	complete
enables	GO:0019901	protein kinase binding	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0010333 FB:FBgn0014011 PANTHER:PTN002784637 RGD:619755 UniProtKB:P63000 dictyBase:DDB_G0293526	F	Seeded From UniProt	complete
involved_in	GO:0016601	Rac protein signal transduction	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN002374567 RGD:619755	P	Seeded From UniProt	complete
involved_in	GO:0016477	cell migration	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0010333 FB:FBgn0014011 MGI:MGI:97845 PANTHER:PTN002784637 RGD:619755 UniProtKB:Q6LC82 WB:WBGene00000424 WB:WBGene00004287 ZFIN:ZDB-GENE-030131-5415 ZFIN:ZDB-GENE-040625-27 dictyBase:DDB_G0293526	P	Seeded From UniProt	complete
involved_in	GO:0008045	motor neuron axon guidance	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0010333 PANTHER:PTN002784640 WB:WBGene00000424 WB:WBGene00004287	P	Seeded From UniProt	complete
involved_in	GO:0007266	Rho protein signal transduction	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0010341 FB:FBgn0014011 MGI:MGI:1931551 PANTHER:PTN000632671 RGD:619921 UniProtKB:I3LVS7 UniProtKB:P61586 UniProtKB:P84095	P	Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0010333 MGI:MGI:97845 PANTHER:PTN002784637 UniProtKB:P63000 WB:WBGene00000424 WB:WBGene00004287	C	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0010333 MGI:MGI:97845 MGI:MGI:97846 PANTHER:PTN002784637 RGD:619755 UniProtKB:P15153 UniProtKB:P63000 WB:WBGene00000424 ZFIN:ZDB-GENE-040625-27 dictyBase:DDB_G0280975 dictyBase:DDB_G0293526	C	Seeded From UniProt	complete
enables	GO:0005525	GTP binding	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0039140 MGI:MGI:108446 MGI:MGI:97845 PANTHER:PTN000632671 RGD:619755 RGD:619921 RGD:71043 SGD:S000001380 TAIR:locus:2131606 TAIR:locus:2204380 UniProtKB:A0A1D8PDV5 UniProtKB:P15153 UniProtKB:P60953 UniProtKB:P61586 UniProtKB:P63000 UniProtKB:Q15669 UniProtKB:Q9SSX0 WB:WBGene00000390 WB:WBGene00000424 WB:WBGene00004287 WB:WBGene00004357	F	Seeded From UniProt	complete
enables	GO:0003924	GTPase activity	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0010333 FB:FBgn0010341 FB:FBgn0014011 FB:FBgn0014020 MGI:MGI:106211 MGI:MGI:1096342 MGI:MGI:1916831 MGI:MGI:97845 MGI:MGI:97846 PANTHER:PTN000632671 PomBase:SPAC110.03 PomBase:SPAC16.01 PomBase:SPAC16A10.04 PomBase:SPAC1F7.04 PomBase:SPAC23C4.08 RGD:619755 RGD:619921 SGD:S000000046 SGD:S000001380 SGD:S000001763 SGD:S000004219 SGD:S000005034 SGD:S000005124 SGD:S000006369 TAIR:locus:2099232 TAIR:locus:2131606 UniProtKB:A0A1D8PCX9 UniProtKB:A0A1D8PH96 UniProtKB:P17081 UniProtKB:P60763 UniProtKB:P60953 UniProtKB:P61586 UniProtKB:P63000 UniProtKB:P84095 UniProtKB:Q5A904 WB:WBGene00000390 WB:WBGene00000424 WB:WBGene00003239 WB:WBGene00004287 WB:WBGene00004357	F	Seeded From UniProt	complete
involved_in	GO:0045859	regulation of protein kinase activity	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0019887	P	Seeded From UniProt	complete
involved_in	GO:1902622	regulation of neutrophil migration	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P15153 ensembl:ENSP00000249071	P	Seeded From UniProt	complete
involved_in	GO:0090023	positive regulation of neutrophil chemotaxis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P15153 ensembl:ENSP00000249071	P	Seeded From UniProt	complete
involved_in	GO:0071593	lymphocyte aggregation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P15153 ensembl:ENSP00000249071	P	Seeded From UniProt	complete
involved_in	GO:0060263	regulation of respiratory burst	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P15153 ensembl:ENSP00000249071	P	Seeded From UniProt	complete
part_of	GO:0030027	lamellipodium	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P15153 ensembl:ENSP00000249071	C	Seeded From UniProt	complete
involved_in	GO:0010810	regulation of cell-substrate adhesion	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P15153 ensembl:ENSP00000249071	P	Seeded From UniProt	complete
involved_in	GO:0010592	positive regulation of lamellipodium assembly	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P15153 ensembl:ENSP00000249071	P	Seeded From UniProt	complete
involved_in	GO:0007015	actin filament organization	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P15153 ensembl:ENSP00000249071	P	Seeded From UniProt	complete
part_of	GO:0005884	actin filament	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P15153 ensembl:ENSP00000249071	C	Seeded From UniProt	complete
part_of	GO:0005829	cytosol	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P15153 ensembl:ENSP00000249071	C	Seeded From UniProt	complete
enables	GO:0005525	GTP binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P15153 ensembl:ENSP00000249071	F	Seeded From UniProt	complete
involved_in	GO:0090023	positive regulation of neutrophil chemotaxis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q05144 ensembl:ENSMUSP00000036384	P	Seeded From UniProt	complete
involved_in	GO:0060753	regulation of mast cell chemotaxis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q05144 ensembl:ENSMUSP00000036384	P	Seeded From UniProt	complete
involved_in	GO:0043304	regulation of mast cell degranulation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q05144 ensembl:ENSMUSP00000036384	P	Seeded From UniProt	complete
involved_in	GO:0042129	regulation of T cell proliferation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q05144 ensembl:ENSMUSP00000036384	P	Seeded From UniProt	complete
involved_in	GO:0030036	actin cytoskeleton organization	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q05144 ensembl:ENSMUSP00000036384	P	Seeded From UniProt	complete
involved_in	GO:0030031	cell projection assembly	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q05144 ensembl:ENSMUSP00000036384	P	Seeded From UniProt	complete
enables	GO:0019887	protein kinase regulator activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q05144 ensembl:ENSMUSP00000036384	F	Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q05144 ensembl:ENSMUSP00000036384	C	Seeded From UniProt	complete
involved_in	GO:0010592	positive regulation of lamellipodium assembly	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q05144 ensembl:ENSMUSP00000036384	P	Seeded From UniProt	complete
involved_in	GO:0008284	positive regulation of cell population proliferation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q05144 ensembl:ENSMUSP00000036384	P	Seeded From UniProt	complete
involved_in	GO:0007186	G protein-coupled receptor signaling pathway	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q05144 ensembl:ENSMUSP00000036384	P	Seeded From UniProt	complete
involved_in	GO:0006935	chemotaxis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q05144 ensembl:ENSMUSP00000036384	P	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q05144 ensembl:ENSMUSP00000036384	C	Seeded From UniProt	complete
part_of	GO:0005635	nuclear envelope	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q05144 ensembl:ENSMUSP00000036384	C	Seeded From UniProt	complete
enables	GO:0003924	GTPase activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q05144 ensembl:ENSMUSP00000036384	F	Seeded From UniProt	complete
enables	GO:0003924	GTPase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001806	F	Seeded From UniProt	complete
enables	GO:0005525	GTP binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001806 InterPro:IPR003578 InterPro:IPR005225	F	Seeded From UniProt	complete
involved_in	GO:0007264	small GTPase mediated signal transduction	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR003578	P	Seeded From UniProt	complete
enables	GO:0000166	nucleotide binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0547	F	Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0472 UniProtKB-SubCell:SL-0162	C	Seeded From UniProt	complete
enables	GO:0005525	GTP binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0342	F	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0963 UniProtKB-SubCell:SL-0086	C	Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.00 ^1.01 ^1.02 ^1.03 ^1.04 ^1.05 ^1.06 ^1.07 ^1.08 ^1.09 ^1.10 ^1.11 ^1.12 ^1.13 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:21873635-1] 1.00 ^1.01 ^1.02 ^1.03 ^1.04 ^1.05 ^1.06 ^1.07 ^1.08 ^1.09 ^1.10 ^1.11 ^1.12 ^1.13 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

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BOVIN:RAC2

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