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CHICK:CCL4

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Species (Taxon ID) Gallus gallus (Chicken). (9031)
Gene Name(s) CCL4 (synonyms: SCYA4)
Protein Name(s) C-C motif chemokine 4 homolog

Macrophage inflammatory protein 1-beta homolog MIP-1-beta Small-inducible cytokine A4 homolog

External Links
UniProt Q90826
EMBL L34553
AJ243034
AY895166
RefSeq NP_001025531.2
UniGene Gga.4409
ProteinModelPortal Q90826
SMR Q90826
Ensembl ENSGALT00000001404
GeneID 395551
KEGG gga:395551
CTD 6351
eggNOG NOG38896
GeneTree ENSGT00730000110278
HOGENOM HOG000036685
HOVERGEN HBG017871
InParanoid Q90826
KO K12964
OMA ICYQTSA
Reactome REACT_297287
REACT_338065
NextBio 20815626
PRO PR:Q90826
Proteomes UP000000539
ExpressionAtlas Q90826
GO GO:0005615
GO:0060326
GO:0006955
InterPro IPR000827
IPR001811
Pfam PF00048
SMART SM00199
SUPFAM SSF54117
PROSITE PS00472

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0071356

cellular response to tumor necrosis factor

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:98259
PANTHER:PTN000245709
RGD:3645
RGD:69069
UniProtKB:P10147
UniProtKB:P13500
UniProtKB:P13501

P

Seeded From UniProt

complete

involved_in

GO:0071347

cellular response to interleukin-1

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:98259
PANTHER:PTN000245709
RGD:3645
UniProtKB:P10147
UniProtKB:P13500
UniProtKB:P13501

P

Seeded From UniProt

complete

involved_in

GO:0071346

cellular response to interferon-gamma

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:98259
PANTHER:PTN000245709
RGD:3645
UniProtKB:P10147
UniProtKB:P13500
UniProtKB:P13501

P

Seeded From UniProt

complete

involved_in

GO:0070374

positive regulation of ERK1 and ERK2 cascade

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000245709
UniProtKB:O00585
UniProtKB:P10147
UniProtKB:Q99731

P

Seeded From UniProt

complete

involved_in

GO:0070098

chemokine-mediated signaling pathway

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000245709
RGD:3645
UniProtKB:P13501
UniProtKB:Q9Y258

P

Seeded From UniProt

complete

involved_in

GO:0048247

lymphocyte chemotaxis

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1097153
PANTHER:PTN000245709
RGD:3645
RGD:69069
UniProtKB:P10147

P

Seeded From UniProt

complete

involved_in

GO:0048245

eosinophil chemotaxis

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001381485
RGD:3644
UniProtKB:O00175
UniProtKB:P51671
UniProtKB:P80098
UniProtKB:Q99616

P

Seeded From UniProt

complete

enables

GO:0048020

CCR chemokine receptor binding

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000245709
UniProtKB:Q99731

F

Seeded From UniProt

complete

involved_in

GO:0043547

positive regulation of GTPase activity

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1346316
PANTHER:PTN000245709
UniProtKB:O00175
UniProtKB:P51671
UniProtKB:Q9Y258

P

Seeded From UniProt

complete

involved_in

GO:0030593

neutrophil chemotaxis

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1097153
PANTHER:PTN000245709
RGD:3645
RGD:3647
UniProtKB:P10147

P

Seeded From UniProt

complete

enables

GO:0008009

chemokine activity

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:104593
MGI:MGI:1097153
MGI:MGI:1099448
MGI:MGI:1346316
MGI:MGI:98260
PANTHER:PTN000245709
RGD:1303200
RGD:3644
RGD:3645
RGD:3646
RGD:3647
RGD:620441
RGD:620458
RGD:69069
UniProtKB:O00175
UniProtKB:O00585
UniProtKB:O15444
UniProtKB:P10147
UniProtKB:P13501
UniProtKB:P22362
UniProtKB:P47992
UniProtKB:P51671
UniProtKB:P55773
UniProtKB:P78423
UniProtKB:P80098
UniProtKB:Q99616
UniProtKB:Q99731
UniProtKB:Q9Y258

F

Seeded From UniProt

complete

involved_in

GO:0007186

G protein-coupled receptor signaling pathway

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000245709
UniProtKB:O00585
UniProtKB:O15444
UniProtKB:P13501

P

Seeded From UniProt

complete

involved_in

GO:0006954

inflammatory response

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:108224
MGI:MGI:98262
PANTHER:PTN000245709
RGD:3645
RGD:3647
RGD:620441
RGD:69069
UniProtKB:P10147
UniProtKB:P13500
UniProtKB:P13501

P

Seeded From UniProt

complete

part_of

GO:0005615

extracellular space

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:101878
MGI:MGI:104593
MGI:MGI:1306779
MGI:MGI:98259
MGI:MGI:98260
MGI:MGI:98261
MGI:MGI:98262
MGI:MGI:99512
PANTHER:PTN000245709
RGD:3644
RGD:3645
RGD:3646
RGD:69069
UniProtKB:P10147
UniProtKB:P22362
UniProtKB:Q9Y258

C

Seeded From UniProt

complete

involved_in

GO:0002548

monocyte chemotaxis

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:108224
PANTHER:PTN000245709
UniProtKB:P10147
UniProtKB:P13500
UniProtKB:Q9Y258

P

Seeded From UniProt

complete

involved_in

GO:0010469

regulation of signaling receptor activity

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0005125

P

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000827
InterPro:IPR001811
InterPro:IPR036048

C

Seeded From UniProt

complete

involved_in

GO:0006955

immune response

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000827
InterPro:IPR001811
InterPro:IPR036048

P

Seeded From UniProt

complete

enables

GO:0008009

chemokine activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000827
InterPro:IPR001811
InterPro:IPR036048
InterPro:IPR039809

F

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0964
UniProtKB-SubCell:SL-0243

C

Seeded From UniProt

complete

involved_in

GO:0006935

chemotaxis

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0145

P

Seeded From UniProt

complete

enables

GO:0005125

cytokine activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0202

F

Seeded From UniProt

complete

part_of

GO:0005615

extracellular space

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0202

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.00 1.01 1.02 1.03 1.04 1.05 1.06 1.07 1.08 1.09 1.10 1.11 1.12 1.13 1.14 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page