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Category:GO:0008009 ! chemokine activity

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DAG for GO:0008009id: GO:0008009

name: chemokine activity
namespace: molecular_function
def: "The function of a family of small chemotactic cytokines; their name is derived from their ability to induce directed chemotaxis in nearby responsive cells. All chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in controlling the migration of cells during normal processes of tissue maintenance or development. Chemokines are found in all vertebrates, some viruses and some bacteria." [GOC:BHF, GOC:rl, http://en.wikipedia.org/wiki/Chemokine, http://www.copewithcytokines.de/cope.cgi?key=Cytokines, PMID:12183377]
comment: See also the molecular function terms 'cytokine activity ; GO:0005125' and 'receptor agonist activity ; GO:0048018'.
subset: goslim_chembl
is_a: GO:0005125 ! cytokine activity
is_a: GO:0042379 ! chemokine receptor binding
relationship: part_of: GO:0060326 ! cell chemotaxis


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