CHICK:Q4KS30

Species (Taxon ID)	Gallus gallus (Chicken). (9031)
Gene Name(s)	CCL4 (ECO:0000313 with Ensembl:ENSGALP00000039852)
Protein Name(s)	C-C motif chemokine 4 homolog (ECO:0000313 with Ensembl:ENSGALP00000039852) Chemokine K203 (ECO:0000313 with EMBL:AAX83392.1)
External Links
UniProt	Q4KS30
EMBL	AADN03007730 AY895166
UniGene	Gga.255
STRING	9031.ENSGALP00000001408
Ensembl	ENSGALT00000040649
eggNOG	NOG124416
GeneTree	ENSGT00730000110278
HOGENOM	HOG000036685
HOVERGEN	HBG017871
OMA	DIPTICC
Proteomes	UP000000539
GO	GO:0005576 GO:0060326 GO:0006955
InterPro	IPR001811
Pfam	PF00048
SMART	SM00199
SUPFAM	SSF54117

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Notes	Status
involved_in	GO:0071356	cellular response to tumor necrosis factor	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:98259 PANTHER:PTN000245709 RGD:3645 RGD:69069 UniProtKB:P10147 UniProtKB:P13500 UniProtKB:P13501	P	Seeded From UniProt	complete
involved_in	GO:0071347	cellular response to interleukin-1	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:98259 PANTHER:PTN000245709 RGD:3645 UniProtKB:P10147 UniProtKB:P13500 UniProtKB:P13501	P	Seeded From UniProt	complete
involved_in	GO:0071346	cellular response to interferon-gamma	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:98259 PANTHER:PTN000245709 RGD:3645 UniProtKB:P10147 UniProtKB:P13500 UniProtKB:P13501	P	Seeded From UniProt	complete
involved_in	GO:0070374	positive regulation of ERK1 and ERK2 cascade	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000245709 UniProtKB:O00585 UniProtKB:P10147 UniProtKB:Q99731	P	Seeded From UniProt	complete
involved_in	GO:0070098	chemokine-mediated signaling pathway	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000245709 RGD:3645 UniProtKB:P13501 UniProtKB:Q9Y258	P	Seeded From UniProt	complete
involved_in	GO:0048247	lymphocyte chemotaxis	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1097153 PANTHER:PTN000245709 RGD:3645 RGD:69069 UniProtKB:P10147	P	Seeded From UniProt	complete
involved_in	GO:0048245	eosinophil chemotaxis	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN001381485 RGD:3644 UniProtKB:O00175 UniProtKB:P51671 UniProtKB:P80098 UniProtKB:Q99616	P	Seeded From UniProt	complete
enables	GO:0048020	CCR chemokine receptor binding	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000245709 UniProtKB:Q99731	F	Seeded From UniProt	complete
involved_in	GO:0043547	positive regulation of GTPase activity	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1346316 PANTHER:PTN000245709 UniProtKB:O00175 UniProtKB:P51671 UniProtKB:Q9Y258	P	Seeded From UniProt	complete
involved_in	GO:0030593	neutrophil chemotaxis	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1097153 PANTHER:PTN000245709 RGD:3645 RGD:3647 UniProtKB:P10147	P	Seeded From UniProt	complete
enables	GO:0008009	chemokine activity	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:104593 MGI:MGI:1097153 MGI:MGI:1099448 MGI:MGI:1346316 MGI:MGI:98260 PANTHER:PTN000245709 RGD:1303200 RGD:3644 RGD:3645 RGD:3646 RGD:3647 RGD:620441 RGD:620458 RGD:69069 UniProtKB:O00175 UniProtKB:O00585 UniProtKB:O15444 UniProtKB:P10147 UniProtKB:P13501 UniProtKB:P22362 UniProtKB:P47992 UniProtKB:P51671 UniProtKB:P55773 UniProtKB:P78423 UniProtKB:P80098 UniProtKB:Q99616 UniProtKB:Q99731 UniProtKB:Q9Y258	F	Seeded From UniProt	complete
involved_in	GO:0007186	G protein-coupled receptor signaling pathway	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000245709 UniProtKB:O00585 UniProtKB:O15444 UniProtKB:P13501	P	Seeded From UniProt	complete
involved_in	GO:0006954	inflammatory response	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:108224 MGI:MGI:98262 PANTHER:PTN000245709 RGD:3645 RGD:3647 RGD:620441 RGD:69069 UniProtKB:P10147 UniProtKB:P13500 UniProtKB:P13501	P	Seeded From UniProt	complete
part_of	GO:0005615	extracellular space	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:101878 MGI:MGI:104593 MGI:MGI:1306779 MGI:MGI:98259 MGI:MGI:98260 MGI:MGI:98261 MGI:MGI:98262 MGI:MGI:99512 PANTHER:PTN000245709 RGD:3644 RGD:3645 RGD:3646 RGD:69069 UniProtKB:P10147 UniProtKB:P22362 UniProtKB:Q9Y258	C	Seeded From UniProt	complete
involved_in	GO:0002548	monocyte chemotaxis	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:108224 PANTHER:PTN000245709 UniProtKB:P10147 UniProtKB:P13500 UniProtKB:Q9Y258	P	Seeded From UniProt	complete
part_of	GO:0005576	extracellular region	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001811 InterPro:IPR036048	C	Seeded From UniProt	complete
involved_in	GO:0006955	immune response	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001811 InterPro:IPR036048	P	Seeded From UniProt	complete
enables	GO:0008009	chemokine activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001811 InterPro:IPR036048 InterPro:IPR039809	F	Seeded From UniProt	complete
involved_in	GO:0030595	leukocyte chemotaxis	PMID:16430960^[2]	ECO:0000304	author statement supported by traceable reference used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0030097	hemopoiesis	PMID:16430960^[2]	ECO:0000304	author statement supported by traceable reference used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0002269	leukocyte activation involved in inflammatory response	PMID:16430960^[2]	ECO:0000304	author statement supported by traceable reference used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0002232	leukocyte chemotaxis involved in inflammatory response	PMID:16430960^[2]	ECO:0000304	author statement supported by traceable reference used in manual assertion		P	Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.00 ^1.01 ^1.02 ^1.03 ^1.04 ^1.05 ^1.06 ^1.07 ^1.08 ^1.09 ^1.10 ^1.11 ^1.12 ^1.13 ^1.14 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
↑ ^2.0 ^2.1 ^2.2 ^2.3 Bar-Shira, E & Friedman, A (2006) Development and adaptations of innate immunity in the gastrointestinal tract of the newly hatched chick. Dev. Comp. Immunol. 30 930-41 PubMed GONUTS page

[PMID:21873635-1] 1.00 ^1.01 ^1.02 ^1.03 ^1.04 ^1.05 ^1.06 ^1.07 ^1.08 ^1.09 ^1.10 ^1.11 ^1.12 ^1.13 ^1.14 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:16430960-2] 2.0 ^2.1 ^2.2 ^2.3 Bar-Shira, E & Friedman, A (2006) Development and adaptations of innate immunity in the gastrointestinal tract of the newly hatched chick. Dev. Comp. Immunol. 30 930-41 PubMed GONUTS page

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CHICK:Q4KS30

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