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MOUSE:CCL25

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Species (Taxon ID) Mus musculus (Mouse). (10090)
Gene Name(s) Ccl25 (synonyms: Scya25, Teck)
Protein Name(s) C-C motif chemokine 25

Chemokine TECK Small-inducible cytokine A25 Thymus-expressed chemokine

External Links
UniProt O35903
EMBL U86357
AJ249480
DQ158256
AK134138
AC155164
BC117033
BC117037
CCDS CCDS22085.1
RefSeq NP_033164.1
UniGene Mm.7275
ProteinModelPortal O35903
SMR O35903
DIP DIP-5885N
IntAct O35903
MINT MINT-106264
STRING 10090.ENSMUSP00000024004
PhosphoSite O35903
PRIDE O35903
Ensembl ENSMUST00000024004
GeneID 20300
KEGG mmu:20300
UCSC uc009ktw.2
CTD 6370
MGI MGI:1099448
eggNOG NOG39655
GeneTree ENSGT00510000049257
HOGENOM HOG000293281
HOVERGEN HBG050832
InParanoid O35903
KO K13072
OMA QGVFEDC
TreeFam TF353160
Reactome REACT_230248
REACT_250376
NextBio 298037
PRO PR:O35903
Proteomes UP000000589
CleanEx MM_CCL25
ExpressionAtlas O35903
Genevestigator O35903
GO GO:0005615
GO:0008009
GO:0042379
GO:0060326
GO:0006935
GO:0006955
GO:0006954
GO:0050900
InterPro IPR001811
Pfam PF00048
SMART SM00199
SUPFAM SSF54117

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

enables

GO:0042379

chemokine receptor binding

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:O15444

F

Seeded From UniProt

complete

involved_in

GO:0071356

cellular response to tumor necrosis factor

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:98259
PANTHER:PTN000245709
RGD:3645
RGD:69069
UniProtKB:P10147
UniProtKB:P13500
UniProtKB:P13501

P

Seeded From UniProt

complete

involved_in

GO:0071347

cellular response to interleukin-1

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:98259
PANTHER:PTN000245709
RGD:3645
UniProtKB:P10147
UniProtKB:P13500
UniProtKB:P13501

P

Seeded From UniProt

complete

involved_in

GO:0071346

cellular response to interferon-gamma

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:98259
PANTHER:PTN000245709
RGD:3645
UniProtKB:P10147
UniProtKB:P13500
UniProtKB:P13501

P

Seeded From UniProt

complete

involved_in

GO:0070374

positive regulation of ERK1 and ERK2 cascade

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000245709
UniProtKB:O00585
UniProtKB:P10147
UniProtKB:Q99731

P

Seeded From UniProt

complete

involved_in

GO:0070098

chemokine-mediated signaling pathway

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000245709
RGD:3645
UniProtKB:P13501
UniProtKB:Q9Y258

P

Seeded From UniProt

complete

involved_in

GO:0048247

lymphocyte chemotaxis

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1097153
PANTHER:PTN000245709
RGD:3645
RGD:69069
UniProtKB:P10147

P

Seeded From UniProt

complete

enables

GO:0048020

CCR chemokine receptor binding

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000245709
UniProtKB:Q99731

F

Seeded From UniProt

complete

involved_in

GO:0043547

positive regulation of GTPase activity

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1346316
PANTHER:PTN000245709
UniProtKB:O00175
UniProtKB:P51671
UniProtKB:Q9Y258

P

Seeded From UniProt

complete

involved_in

GO:0030593

neutrophil chemotaxis

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1097153
PANTHER:PTN000245709
RGD:3645
RGD:3647
UniProtKB:P10147

P

Seeded From UniProt

complete

enables

GO:0008009

chemokine activity

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:104593
MGI:MGI:1097153
MGI:MGI:1099448
MGI:MGI:1346316
MGI:MGI:98260
PANTHER:PTN000245709
RGD:1303200
RGD:3644
RGD:3645
RGD:3646
RGD:3647
RGD:620441
RGD:620458
RGD:69069
UniProtKB:O00175
UniProtKB:O00585
UniProtKB:O15444
UniProtKB:P10147
UniProtKB:P13501
UniProtKB:P22362
UniProtKB:P47992
UniProtKB:P51671
UniProtKB:P55773
UniProtKB:P78423
UniProtKB:P80098
UniProtKB:Q99616
UniProtKB:Q99731
UniProtKB:Q9Y258

F

Seeded From UniProt

complete

involved_in

GO:0007186

G protein-coupled receptor signaling pathway

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000245709
UniProtKB:O00585
UniProtKB:O15444
UniProtKB:P13501

P

Seeded From UniProt

complete

involved_in

GO:0006954

inflammatory response

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:108224
MGI:MGI:98262
PANTHER:PTN000245709
RGD:3645
RGD:3647
RGD:620441
RGD:69069
UniProtKB:P10147
UniProtKB:P13500
UniProtKB:P13501

P

Seeded From UniProt

complete

part_of

GO:0005615

extracellular space

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:101878
MGI:MGI:104593
MGI:MGI:1306779
MGI:MGI:98259
MGI:MGI:98260
MGI:MGI:98261
MGI:MGI:98262
MGI:MGI:99512
PANTHER:PTN000245709
RGD:3644
RGD:3645
RGD:3646
RGD:69069
UniProtKB:P10147
UniProtKB:P22362
UniProtKB:Q9Y258

C

Seeded From UniProt

complete

involved_in

GO:0002548

monocyte chemotaxis

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:108224
PANTHER:PTN000245709
UniProtKB:P10147
UniProtKB:P13500
UniProtKB:Q9Y258

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:1903237

negative regulation of leukocyte tethering or rolling

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:O15444

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0060326

cell chemotaxis

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:O15444

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0050900

leukocyte migration

PMID:15358618[2]

ECO:0000314

direct assay evidence used in manual assertion

P

  • occurs_in:(EMAPA:17523)
  • results_in_movement_of:(CL:0000827)

Seeded From UniProt

complete

enables

GO:0042379

chemokine receptor binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:O15444

F

Seeded From UniProt

complete

enables

GO:0031735

CCR10 chemokine receptor binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:O15444

F

Seeded From UniProt

complete

enables

GO:0008009

chemokine activity

PMID:10623805[3]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0008009

chemokine activity

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:O15444

F

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0007186

G protein-coupled receptor signaling pathway

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:O15444

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0006935

chemotaxis

PMID:10623805[3]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0001954

positive regulation of cell-matrix adhesion

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:O15444

P

Seeded From UniProt

complete

involved_in

GO:0010469

regulation of signaling receptor activity

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0005125

P

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001811
InterPro:IPR036048

C

Seeded From UniProt

complete

involved_in

GO:0006955

immune response

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001811
InterPro:IPR036048

P

Seeded From UniProt

complete

enables

GO:0008009

chemokine activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001811
InterPro:IPR036048
InterPro:IPR039809

F

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0964
UniProtKB-SubCell:SL-0243

C

Seeded From UniProt

complete

involved_in

GO:0006935

chemotaxis

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0145

P

Seeded From UniProt

complete

part_of

GO:0005615

extracellular space

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0202

C

Seeded From UniProt

complete

enables

GO:0005125

cytokine activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0202

F

Seeded From UniProt

complete

involved_in

GO:0006954

inflammatory response

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0395

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.00 1.01 1.02 1.03 1.04 1.05 1.06 1.07 1.08 1.09 1.10 1.11 1.12 1.13 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
  2. Liu, C et al. (2005) The role of CCL21 in recruitment of T-precursor cells to fetal thymi. Blood 105 31-9 PubMed GONUTS page
  3. 3.0 3.1 Norment, AM et al. (2000) Murine CCR9, a chemokine receptor for thymus-expressed chemokine that is up-regulated following pre-TCR signaling. J. Immunol. 164 639-48 PubMed GONUTS page