HUMAN:SDF1

Species (Taxon ID)	Homo sapiens (Human). (9606)
Gene Name(s)	CXCL12 (synonyms: SDF1, SDF1A, SDF1B)
Protein Name(s)	Stromal cell-derived factor 1 SDF-1 hSDF-1 C-X-C motif chemokine 12 Intercrine reduced in hepatomas IRH hIRH Pre-B cell growth-stimulating factor PBSF SDF-1-beta(3-72) SDF-1-alpha(3-67)
External Links
UniProt	P48061
EMBL	L36033 L36034 DQ345517 DQ345518 DQ345519 DQ345520 U16752 U19495 AY644456 AY874118 CR450283 AK292628 AK311814 AU120056 AY802782 AL137026 AL137026 CH471160 BC039893
CCDS	CCDS31186.1 CCDS44373.1 CCDS53527.1 CCDS60518.1 CCDS7207.1
PIR	G01540
RefSeq	NP_000600.1 NP_001029058.1 NP_001171605.1 NP_001264919.1 NP_954637.1
UniGene	Hs.522891
PDB	1A15 1QG7 1SDF 1VMC 2J7Z 2K01 2K03 2K04 2K05 2KEC 2KED 2KEE 2KOL 2NWG 2SDF 3GV3 3HP3 4LMQ 4UAI
PDBsum	1A15 1QG7 1SDF 1VMC 2J7Z 2K01 2K03 2K04 2K05 2KEC 2KED 2KEE 2KOL 2NWG 2SDF 3GV3 3HP3 4LMQ 4UAI
ProteinModelPortal	P48061
SMR	P48061
BioGrid	112288
DIP	DIP-391N DIP-5894N DIP-5895N
IntAct	P48061
MINT	MINT-6491347
STRING	9606.ENSP00000363548
BindingDB	P48061
DrugBank	DB06822
PhosphoSite	P48061
DMDM	1352728
PaxDb	P48061
PRIDE	P48061
Ensembl	ENST00000343575 ENST00000374426 ENST00000374429 ENST00000395793 ENST00000395794 ENST00000395795
GeneID	6387
KEGG	hsa:6387
UCSC	uc001jbf.4 uc001jbh.3 uc021ppm.1
CTD	6387
GeneCards	GC10M044865
H-InvDB	HIX0008784
HGNC	HGNC:10672
HPA	CAB017564
MIM	600835
neXtProt	NX_P48061
PharmGKB	PA35602
eggNOG	NOG26489
GeneTree	ENSGT00390000014056
HOGENOM	HOG000220915
HOVERGEN	HBG107437
InParanoid	P48061
KO	K10031
OMA	HVARANI
OrthoDB	EOG7C5MBS
PhylomeDB	P48061
TreeFam	TF353159
Reactome	REACT_116022 REACT_15344 REACT_19231
ChiTaRS	CXCL12
EvolutionaryTrace	P48061
GeneWiki	Stromal_cell-derived_factor-1
GenomeRNAi	6387
NextBio	24808
PMAP-CutDB	Q5IT36
PRO	PR:P48061
Proteomes	UP000005640
Bgee	P48061
CleanEx	HS_CXCL12
Genevestigator	P48061
GO	GO:0009897 GO:0005576 GO:0005615 GO:0070062 GO:0008009 GO:0042379 GO:0045236 GO:0005102 GO:0008344 GO:0001667 GO:0008015 GO:0007155 GO:0060326 GO:0006874 GO:0070098 GO:0006935 GO:0007186 GO:0007281 GO:0008354 GO:0006955 GO:0050930 GO:0008045 GO:1902230 GO:2000107 GO:1903237 GO:0001764 GO:0031100 GO:0001569 GO:0048842 GO:0090280 GO:0045785 GO:0033603 GO:0001938 GO:0090026 GO:2000406 GO:0008064 GO:0009408 GO:0001666 GO:0009612 GO:0043434 GO:0009314 GO:0009615 GO:0007165 GO:0042098 GO:0022029
InterPro	IPR001811
Pfam	PF00048
SMART	SM00199
SUPFAM	SSF54117

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0008283	cell proliferation	PMID:2684108^[1]	ECO:0000314			P		Figure 3 shows that the different concentration of CXCL12 effect the overall proliferation of the cell.	complete CACAO 5626
	GO:0042148	strand invasion	PMID:2684108^[1]	ECO:0000314			P		Figure 6 shows that from the data collected, CXCL12 invades tumor cells and will cause the formation of CXCL8 products.	complete CACAO 5629
involved_in	GO:0038146	chemokine (C-X-C motif) ligand 12 signaling pathway	PMID:27400149^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	occurs_in:(CL:0000084) part_of:(GO:1990869) part_of:(GO:0010820)	Seeded From UniProt	complete
enables	GO:0008009	chemokine activity	PMID:27400149^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		F	occurs_in:(CL:0000084)	Seeded From UniProt	complete
part_of	GO:0062023	collagen-containing extracellular matrix	PMID:25037231^[3]	ECO:0007005	high throughput direct assay evidence used in manual assertion		C	part_of:(UBERON:0002107)	Seeded From UniProt	complete
part_of	GO:0062023	collagen-containing extracellular matrix	PMID:25037231^[3]	ECO:0007005	high throughput direct assay evidence used in manual assertion		C	part_of:(UBERON:0001155)	Seeded From UniProt	complete
involved_in	GO:0033622	integrin activation	PMID:29301984^[4]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0005178	integrin binding	PMID:29301984^[4]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
involved_in	GO:1990869	cellular response to chemokine	PMID:27400149^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	occurs_in:(CL:0000084) has_input:(UniProtKB:P48061)	Seeded From UniProt	complete
involved_in	GO:0060326	cell chemotaxis	PMID:18308860^[5]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0008009	chemokine activity	PMID:18308860^[5]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
involved_in	GO:1903237	negative regulation of leukocyte tethering or rolling	PMID:18308860^[5]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0070062	extracellular exosome	PMID:23533145^[6]	ECO:0007005	high throughput direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:2000669	negative regulation of dendritic cell apoptotic process	PMID:15059845^[7]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:1902230	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage	PMID:20388803^[8]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0070098	chemokine-mediated signaling pathway	PMID:20388803^[8]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0045236	CXCR chemokine receptor binding	PMID:20388803^[8]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
involved_in	GO:0090026	positive regulation of monocyte chemotaxis	PMID:18802065^[9]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0042379	chemokine receptor binding	PMID:22457824^[10]	ECO:0000315	mutant phenotype evidence used in manual assertion		F		Seeded From UniProt	complete
involved_in	GO:0070098	chemokine-mediated signaling pathway	PMID:21873635^[11]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000428507 UniProtKB:P48061	P		Seeded From UniProt	complete
involved_in	GO:0060326	cell chemotaxis	PMID:21873635^[11]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000428507 UniProtKB:P48061	P		Seeded From UniProt	complete
involved_in	GO:0050930	induction of positive chemotaxis	PMID:21873635^[11]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:103556 PANTHER:PTN000428507	P		Seeded From UniProt	complete
enables	GO:0045236	CXCR chemokine receptor binding	PMID:21873635^[11]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000428507 UniProtKB:P48061	F		Seeded From UniProt	complete
involved_in	GO:0030335	positive regulation of cell migration	PMID:21873635^[11]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:103556 PANTHER:PTN000428507 RGD:3651 UniProtKB:A0A1D5P4F0	P		Seeded From UniProt	complete
part_of	GO:0009897	external side of plasma membrane	PMID:21873635^[11]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:103556 PANTHER:PTN000428507	C		Seeded From UniProt	complete
enables	GO:0008009	chemokine activity	PMID:21873635^[11]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:103556 PANTHER:PTN000428507 UniProtKB:A0A1D5P4F0 UniProtKB:P48061	F		Seeded From UniProt	complete
involved_in	GO:2000406	positive regulation of T cell migration	PMID:23620790^[12]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0045785	positive regulation of cell adhesion	PMID:23620790^[12]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0010469	regulation of signaling receptor activity	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0005125	P		Seeded From UniProt	complete
involved_in	GO:0010469	regulation of signaling receptor activity	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0008083	P		Seeded From UniProt	complete
involved_in	GO:1990478	response to ultrasound	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q80YV8 ensembl:ENSRNOP00000059574	P		Seeded From UniProt	complete
involved_in	GO:0051924	regulation of calcium ion transport	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q80YV8 ensembl:ENSRNOP00000059574	P		Seeded From UniProt	complete
involved_in	GO:0050966	detection of mechanical stimulus involved in sensory perception of pain	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q80YV8 ensembl:ENSRNOP00000059574	P		Seeded From UniProt	complete
involved_in	GO:0050965	detection of temperature stimulus involved in sensory perception of pain	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q80YV8 ensembl:ENSRNOP00000059574	P		Seeded From UniProt	complete
involved_in	GO:0048842	positive regulation of axon extension involved in axon guidance	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q80YV8 ensembl:ENSRNOP00000059574	P		Seeded From UniProt	complete
involved_in	GO:0045666	positive regulation of neuron differentiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q80YV8 ensembl:ENSRNOP00000059574	P		Seeded From UniProt	complete
involved_in	GO:0043434	response to peptide hormone	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q80YV8 ensembl:ENSRNOP00000059574	P		Seeded From UniProt	complete
involved_in	GO:0033603	positive regulation of dopamine secretion	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q80YV8 ensembl:ENSRNOP00000059574	P		Seeded From UniProt	complete
involved_in	GO:0031100	animal organ regeneration	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q80YV8 ensembl:ENSRNOP00000059574	P		Seeded From UniProt	complete
involved_in	GO:0030335	positive regulation of cell migration	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q80YV8 ensembl:ENSRNOP00000059574	P		Seeded From UniProt	complete
involved_in	GO:0022029	telencephalon cell migration	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q80YV8 ensembl:ENSRNOP00000059574	P		Seeded From UniProt	complete
involved_in	GO:0009612	response to mechanical stimulus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q80YV8 ensembl:ENSRNOP00000059574	P		Seeded From UniProt	complete
involved_in	GO:0009408	response to heat	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q80YV8 ensembl:ENSRNOP00000059574	P		Seeded From UniProt	complete
involved_in	GO:0009314	response to radiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q80YV8 ensembl:ENSRNOP00000059574	P		Seeded From UniProt	complete
involved_in	GO:0008344	adult locomotory behavior	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q80YV8 ensembl:ENSRNOP00000059574	P		Seeded From UniProt	complete
involved_in	GO:0008284	positive regulation of cell population proliferation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q80YV8 ensembl:ENSRNOP00000059574	P		Seeded From UniProt	complete
involved_in	GO:0007420	brain development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q80YV8 ensembl:ENSRNOP00000059574	P		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q80YV8 ensembl:ENSRNOP00000059574	C		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q80YV8 ensembl:ENSRNOP00000059574	C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q80YV8 ensembl:ENSRNOP00000059574	C		Seeded From UniProt	complete
part_of	GO:0005615	extracellular space	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q80YV8 ensembl:ENSRNOP00000059574	C		Seeded From UniProt	complete
involved_in	GO:0001938	positive regulation of endothelial cell proliferation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q80YV8 ensembl:ENSRNOP00000059574	P		Seeded From UniProt	complete
involved_in	GO:0001764	neuron migration	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q80YV8 ensembl:ENSRNOP00000059574	P		Seeded From UniProt	complete
involved_in	GO:0001666	response to hypoxia	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q80YV8 ensembl:ENSRNOP00000059574	P		Seeded From UniProt	complete
part_of	GO:0005576	extracellular region	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001811 InterPro:IPR036048	C		Seeded From UniProt	complete
involved_in	GO:0006935	chemotaxis	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR033899	P		Seeded From UniProt	complete
involved_in	GO:0006952	defense response	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR033899	P		Seeded From UniProt	complete
involved_in	GO:0006955	immune response	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001811 InterPro:IPR036048	P		Seeded From UniProt	complete
enables	GO:0008009	chemokine activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001811 InterPro:IPR033899 InterPro:IPR036048 InterPro:IPR039813	F		Seeded From UniProt	complete
involved_in	GO:0070098	chemokine-mediated signaling pathway	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR039813	P		Seeded From UniProt	complete
involved_in	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide	PMID:12949249^[13]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0031640	killing of cells of other organism	PMID:12949249^[13]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0031640	killing of cells of other organism	PMID:12949249^[13]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0010818	T cell chemotaxis	PMID:17088326^[14]	ECO:0000314	direct assay evidence used in manual assertion		P	results_in_movement_of:(CL:0000492) part_of:(CL:2000001)	Seeded From UniProt	complete
involved_in	GO:0090280	positive regulation of calcium ion import	PMID:10925302^[15]	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0009615	response to virus	PMID:10772939^[16]	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0008064	regulation of actin polymerization or depolymerization	PMID:10570282^[17]	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0008015	blood circulation	PMID:10772939^[16]	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0008009	chemokine activity	PMID:10772939^[16] PMID:12782716^[18]	ECO:0000304	author statement supported by traceable reference used in manual assertion		F		Seeded From UniProt	complete
involved_in	GO:0007186	G protein-coupled receptor signaling pathway	PMID:8752280^[19] Reactome:R-HSA-388396	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0007165	signal transduction	PMID:10491003^[20]	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0007155	cell adhesion	PMID:10198043^[21]	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0006955	immune response	PMID:10802710^[22]	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0006935	chemotaxis	PMID:10620615^[23] PMID:12782716^[18]	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0006874	cellular calcium ion homeostasis	PMID:10772939^[16]	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0005102	signaling receptor binding	PMID:10438529^[24] PMID:10358157^[25]	ECO:0000304	author statement supported by traceable reference used in manual assertion		F		Seeded From UniProt	complete
involved_in	GO:0007411	axon guidance	Reactome:R-HSA-422475	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005576	extracellular region	Reactome:R-HSA-8986258 Reactome:R-HSA-8954199 Reactome:R-HSA-749456 Reactome:R-HSA-749454 Reactome:R-HSA-380073 Reactome:R-HSA-374214	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
enables	GO:0008083	growth factor activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0339	F		Seeded From UniProt	complete
enables	GO:0005125	cytokine activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0202	F		Seeded From UniProt	complete
involved_in	GO:0016032	viral process	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0945	P		Seeded From UniProt	complete
involved_in	GO:0006935	chemotaxis	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0145	P		Seeded From UniProt	complete
part_of	GO:0005576	extracellular region	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0964 UniProtKB-SubCell:SL-0243	C		Seeded From UniProt	complete
part_of	GO:0005615	extracellular space	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0202	C		Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 Van Huynh, T et al. (1989) Reduced protein kinase C immunoreactivity and altered protein phosphorylation in Alzheimer's disease fibroblasts. Arch. Neurol. 46 1195-9 PubMed GONUTS page
↑ ^2.0 ^2.1 ^2.2 Köchl, R et al. (2016) WNK1 kinase balances T cell adhesion versus migration in vivo. Nat. Immunol. 17 1075-83 PubMed GONUTS page
↑ ^3.0 ^3.1 Naba, A et al. (2014) Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver. BMC Cancer 14 518 PubMed GONUTS page
↑ ^4.0 ^4.1 Fujita, M et al. (2018) Stromal cell-derived factor-1 (CXCL12) activates integrins by direct binding to an allosteric ligand-binding site (site 2) of integrins without CXCR4. Biochem. J. 475 723-732 PubMed GONUTS page
↑ ^5.0 ^5.1 ^5.2 Miles, A et al. (2008) CCL25 and CCL28 promote alpha4 beta7-integrin-dependent adhesion of lymphocytes to MAdCAM-1 under shear flow. Am. J. Physiol. Gastrointest. Liver Physiol. 294 G1257-67 PubMed GONUTS page
↑ Principe, S et al. (2013) In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine. Proteomics 13 1667-71 PubMed GONUTS page
↑ Sánchez-Sánchez, N et al. (2004) Chemokine receptor CCR7 induces intracellular signaling that inhibits apoptosis of mature dendritic cells. Blood 104 619-25 PubMed GONUTS page
↑ ^8.0 ^8.1 ^8.2 Hattermann, K et al. (2010) The chemokine receptor CXCR7 is highly expressed in human glioma cells and mediates antiapoptotic effects. Cancer Res. 70 3299-308 PubMed GONUTS page
↑ Malik, M et al. (2008) Monocyte migration and LFA-1-mediated attachment to brain microvascular endothelia is regulated by SDF-1 alpha through Lyn kinase. J. Immunol. 181 4632-7 PubMed GONUTS page
↑ Canals, M et al. (2012) Ubiquitination of CXCR7 controls receptor trafficking. PLoS ONE 7 e34192 PubMed GONUTS page
↑ ^11.0 ^11.1 ^11.2 ^11.3 ^11.4 ^11.5 ^11.6 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
↑ ^12.0 ^12.1 Chiang, YJ et al. (2013) CBAP functions as a novel component in chemokine-induced ZAP70-mediated T-cell adhesion and migration. PLoS ONE 8 e61761 PubMed GONUTS page
↑ ^13.0 ^13.1 ^13.2 Yang, D et al. (2003) Many chemokines including CCL20/MIP-3alpha display antimicrobial activity. J. Leukoc. Biol. 74 448-55 PubMed GONUTS page
↑ Szyk, A et al. (2006) Crystal structures of human alpha-defensins HNP4, HD5, and HD6. Protein Sci. 15 2749-60 PubMed GONUTS page
↑ Sano, H et al. (2000) Human galectin-3 is a novel chemoattractant for monocytes and macrophages. J. Immunol. 165 2156-64 PubMed GONUTS page
↑ ^16.0 ^16.1 ^16.2 ^16.3 Ghezzi, S et al. (2000) Inhibition of CXCR4-dependent HIV-1 infection by extracellular HIV-1 Tat. Biochem. Biophys. Res. Commun. 270 992-6 PubMed GONUTS page
↑ Sotsios, Y et al. (1999) The CXC chemokine stromal cell-derived factor activates a Gi-coupled phosphoinositide 3-kinase in T lymphocytes. J. Immunol. 163 5954-63 PubMed GONUTS page
↑ ^18.0 ^18.1 Lasagni, L et al. (2003) An alternatively spliced variant of CXCR3 mediates the inhibition of endothelial cell growth induced by IP-10, Mig, and I-TAC, and acts as functional receptor for platelet factor 4. J. Exp. Med. 197 1537-49 PubMed GONUTS page
↑ Bleul, CC et al. (1996) The lymphocyte chemoattractant SDF-1 is a ligand for LESTR/fusin and blocks HIV-1 entry. Nature 382 829-33 PubMed GONUTS page
↑ Vicente-Manzanares, M et al. (1999) Involvement of phosphatidylinositol 3-kinase in stromal cell-derived factor-1 alpha-induced lymphocyte polarization and chemotaxis. J. Immunol. 163 4001-12 PubMed GONUTS page
↑ Weber, KS et al. (1999) Specific activation of leukocyte beta2 integrins lymphocyte function-associated antigen-1 and Mac-1 by chemokines mediated by distinct pathways via the alpha subunit cytoplasmic domains. Mol. Biol. Cell 10 861-73 PubMed GONUTS page
↑ Poznansky, MC et al. (2000) Active movement of T cells away from a chemokine. Nat. Med. 6 543-8 PubMed GONUTS page
↑ Lüttichau, HR et al. (2000) A highly selective CC chemokine receptor (CCR)8 antagonist encoded by the poxvirus molluscum contagiosum. J. Exp. Med. 191 171-80 PubMed GONUTS page
↑ Kozak, SL et al. (1999) Roles of CD4 and coreceptors in binding, endocytosis, and proteolysis of gp120 envelope glycoproteins derived from human immunodeficiency virus type 1. J. Biol. Chem. 274 23499-507 PubMed GONUTS page
↑ Su, SB et al. (1999) Inhibition of tyrosine kinase activation blocks the down-regulation of CXC chemokine receptor 4 by HIV-1 gp120 in CD4+ T cells. J. Immunol. 162 7128-32 PubMed GONUTS page

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[PMID:10802710-22] Poznansky, MC et al. (2000) Active movement of T cells away from a chemokine. Nat. Med. 6 543-8 PubMed GONUTS page

[PMID:10620615-23] Lüttichau, HR et al. (2000) A highly selective CC chemokine receptor (CCR)8 antagonist encoded by the poxvirus molluscum contagiosum. J. Exp. Med. 191 171-80 PubMed GONUTS page

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