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CHICK:ACM4

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Species (Taxon ID) Gallus gallus (Chicken). (9031)
Gene Name(s) CHRM4
Protein Name(s) Muscarinic acetylcholine receptor M4
External Links
UniProt P17200
EMBL J05218
PIR A35546
RefSeq NP_001026362.1
UniGene Gga.32110
ProteinModelPortal P17200
STRING 9031.ENSGALP00000013605
BindingDB P17200
PaxDb P17200
GeneID 423195
KEGG gga:423195
CTD 1132
eggNOG NOG250863
HOGENOM HOG000231484
HOVERGEN HBG105720
InParanoid P17200
KO K04132
PhylomeDB P17200
NextBio 20825697
PRO PR:P17200
Proteomes UP000000539
GO GO:0030054
GO:0016021
GO:0005887
GO:0045211
GO:0016907
GO:0007213
GO:0007194
GO:0046488
GO:0040012
InterPro IPR000276
IPR017452
IPR001432
IPR000995
PANTHER PTHR24249:SF60
Pfam PF00001
PRINTS PR00237
PR00243
PR00541
PROSITE PS00237
PS50262

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0046488

phosphatidylinositol metabolic process

PMID:2154460[1]

ECO:0000303

author statement without traceable support used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0016907

G protein-coupled acetylcholine receptor activity

PMID:2154460[1]

ECO:0000303

author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0007194

negative regulation of adenylate cyclase activity

PMID:2154460[1]

ECO:0000303

author statement without traceable support used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0071880

adenylate cyclase-activating adrenergic receptor signaling pathway

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001205212
UniProtKB:P08588
UniProtKB:P18871

P

Seeded From UniProt

complete

involved_in

GO:0007188

adenylate cyclase-modulating G protein-coupled receptor signaling pathway

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000664502
RGD:2520

P

Seeded From UniProt

complete

part_of

GO:0005887

integral component of plasma membrane

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0004514
FB:FBgn0035538
FB:FBgn0038541
FB:FBgn0038542
PANTHER:PTN000664502
UniProtKB:P07550
UniProtKB:P08913
UniProtKB:P14416
UniProtKB:P18825
UniProtKB:P18871
UniProtKB:P35462
WB:WBGene00004777

C

Seeded From UniProt

complete

enables

GO:0004935

adrenergic receptor activity

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:87934
MGI:MGI:87935
PANTHER:PTN000664502

F

Seeded From UniProt

complete

involved_in

GO:0007213

G protein-coupled acetylcholine receptor signaling pathway

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0016907

P

Seeded From UniProt

complete

involved_in

GO:0007213

G protein-coupled acetylcholine receptor signaling pathway

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0016907

P

Seeded From UniProt

complete

enables

GO:0004930

G protein-coupled receptor activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000276

F

Seeded From UniProt

complete

part_of

GO:0005887

integral component of plasma membrane

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000995
InterPro:IPR001432

C

Seeded From UniProt

complete

involved_in

GO:0007186

G protein-coupled receptor signaling pathway

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000276
InterPro:IPR000995
InterPro:IPR001432

P

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000276
InterPro:IPR017452

C

Seeded From UniProt

complete

enables

GO:0016907

G protein-coupled acetylcholine receptor activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000995
InterPro:IPR001432

F

Seeded From UniProt

complete

involved_in

GO:0040012

regulation of locomotion

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001432

P

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1003
UniProtKB-SubCell:SL-0039

C

Seeded From UniProt

complete

involved_in

GO:0007186

G protein-coupled receptor signaling pathway

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0297

P

Seeded From UniProt

complete

part_of

GO:0045202

synapse

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0770

C

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

part_of

GO:0030054

cell junction

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0965

C

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

part_of

GO:0045211

postsynaptic membrane

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0628
UniProtKB-SubCell:SL-0219

C

Seeded From UniProt

complete

enables

GO:0004930

G protein-coupled receptor activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0297

F

Seeded From UniProt

complete

involved_in

GO:0007165

signal transduction

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0807

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 Tietje, KM et al. (1990) Cloning and functional analysis of a gene encoding a novel muscarinic acetylcholine receptor expressed in chick heart and brain. J. Biol. Chem. 265 2828-34 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page