CHICK:Q2AB83

Species (Taxon ID)	Gallus gallus (Chicken). (9031)
Gene Name(s)	No Information Provided.
Protein Name(s)	Taste receptor type 2 (ECO:0000256 with RuleBase:RU004424)
External Links
UniProt	Q2AB83
EMBL	AB249766
RefSeq	XP_004938201.1
ProteinModelPortal	Q2AB83
GeneID	101749182
KEGG	gga:101749182
eggNOG	NOG28890
HOGENOM	HOG000234595
HOVERGEN	HBG060698
KO	K08474
PhylomeDB	Q2AB83
GO	GO:0016021 GO:0004930 GO:0050909
InterPro	IPR007960
PANTHER	PTHR11394
Pfam	PF05296

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
enables	GO:0033038	bitter taste receptor activity	PMID:28811548^[1]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0004930	G protein-coupled receptor activity	PMID:28811548^[1]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
involved_in	GO:1904560	response to diphenidol	PMID:25796330^[2]	ECO:0000314	direct assay evidence used in manual assertion		P	part_of:(GO:1904561)	Seeded From UniProt	complete
involved_in	GO:1904558	response to dextromethorphan	PMID:25796330^[2]	ECO:0000314	direct assay evidence used in manual assertion		P	part_of:(GO:1904559)	Seeded From UniProt	complete
enables	GO:0033038	bitter taste receptor activity	PMID:25796330^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		F	part_of:(GO:1904559)\|part_of:(GO:1904561)	Seeded From UniProt	complete
involved_in	GO:1902656	calcium ion import into cytosol	PMID:25796330^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	part_of:(GO:1904559)\|part_of:(GO:1904561)	Seeded From UniProt	complete
involved_in	GO:0080184	response to phenylpropanoid	PMID:25180257^[3]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0071316	cellular response to nicotine	PMID:25180257^[3]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:1904561	cellular response to diphenidol	PMID:25180257^[3]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:1902350	cellular response to chloroquine	PMID:25180257^[3]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0072747	cellular response to chloramphenicol	PMID:25180257^[3]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0097237	cellular response to toxic substance	PMID:25180257^[3]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0035690	cellular response to drug	PMID:25180257^[3]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0033038	bitter taste receptor activity	PMID:25180257^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		F		Seeded From UniProt	complete
involved_in	GO:1902656	calcium ion import into cytosol	PMID:25180257^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0033038	bitter taste receptor activity	PMID:21873635^[4]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000149628 UniProtKB:P59533 UniProtKB:P59534 UniProtKB:P59535 UniProtKB:P59536 UniProtKB:P59537 UniProtKB:P59538 UniProtKB:P59539 UniProtKB:P59540 UniProtKB:P59541 UniProtKB:P59542 UniProtKB:P59544 UniProtKB:P59551 UniProtKB:Q2AB81 UniProtKB:Q2AB82 UniProtKB:Q2AB83 UniProtKB:Q7RTR8 UniProtKB:Q9NYV7 UniProtKB:Q9NYV8 UniProtKB:Q9NYV9 UniProtKB:Q9NYW0 UniProtKB:Q9NYW2 UniProtKB:Q9NYW3 UniProtKB:Q9NYW4 UniProtKB:Q9NYW5 UniProtKB:Q9NYW6 UniProtKB:Q9NYW7	F		Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	PMID:21873635^[4]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000149628 UniProtKB:P59536 UniProtKB:P59539 UniProtKB:P59542 UniProtKB:P59551 UniProtKB:Q7RTR8	C		Seeded From UniProt	complete
involved_in	GO:0001580	detection of chemical stimulus involved in sensory perception of bitter taste	PMID:21873635^[4]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000149628 RGD:1359393 UniProtKB:P59533 UniProtKB:P59534 UniProtKB:P59535 UniProtKB:P59536 UniProtKB:P59537 UniProtKB:P59538 UniProtKB:P59539 UniProtKB:P59540 UniProtKB:P59541 UniProtKB:P59542 UniProtKB:P59544 UniProtKB:P59551 UniProtKB:Q7RTR8 UniProtKB:Q9NYV7 UniProtKB:Q9NYV8 UniProtKB:Q9NYV9 UniProtKB:Q9NYW0 UniProtKB:Q9NYW2 UniProtKB:Q9NYW3 UniProtKB:Q9NYW4 UniProtKB:Q9NYW5 UniProtKB:Q9NYW6 UniProtKB:Q9NYW7	P		Seeded From UniProt	complete
enables	GO:0004930	G protein-coupled receptor activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR007960	F		Seeded From UniProt	complete
involved_in	GO:0007186	G protein-coupled receptor signaling pathway	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR007960	P		Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR007960	C		Seeded From UniProt	complete
involved_in	GO:0050909	sensory perception of taste	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR007960	P		Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0472	C		Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0812	C		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-1003 UniProtKB-SubCell:SL-0039	C		Seeded From UniProt	complete
involved_in	GO:0050896	response to stimulus	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0716	P		Seeded From UniProt	complete
involved_in	GO:0007186	G protein-coupled receptor signaling pathway	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0297	P		Seeded From UniProt	complete
involved_in	GO:0050909	sensory perception of taste	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0919	P		Seeded From UniProt	complete
enables	GO:0004930	G protein-coupled receptor activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0297	F		Seeded From UniProt	complete
involved_in	GO:0007165	signal transduction	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0807	P		Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 Di Pizio, A et al. (2017) Ligand binding modes from low resolution GPCR models and mutagenesis: chicken bitter taste receptor as a test-case. Sci Rep 7 8223 PubMed GONUTS page
↑ ^2.0 ^2.1 ^2.2 ^2.3 Hirose, N et al. (2015) Bitter taste receptor T2R1 activities were compatible with behavioral sensitivity to bitterness in chickens. Biochem. Biophys. Res. Commun. 460 464-8 PubMed GONUTS page
↑ ^3.0 ^3.1 ^3.2 ^3.3 ^3.4 ^3.5 ^3.6 ^3.7 ^3.8 Behrens, M et al. (2014) Tuning properties of avian and frog bitter taste receptors dynamically fit gene repertoire sizes. Mol. Biol. Evol. 31 3216-27 PubMed GONUTS page
↑ ^4.0 ^4.1 ^4.2 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:28811548-1] 1.0 ^1.1 Di Pizio, A et al. (2017) Ligand binding modes from low resolution GPCR models and mutagenesis: chicken bitter taste receptor as a test-case. Sci Rep 7 8223 PubMed GONUTS page

[PMID:25796330-2] 2.0 ^2.1 ^2.2 ^2.3 Hirose, N et al. (2015) Bitter taste receptor T2R1 activities were compatible with behavioral sensitivity to bitterness in chickens. Biochem. Biophys. Res. Commun. 460 464-8 PubMed GONUTS page

[PMID:25180257-3] 3.0 ^3.1 ^3.2 ^3.3 ^3.4 ^3.5 ^3.6 ^3.7 ^3.8 Behrens, M et al. (2014) Tuning properties of avian and frog bitter taste receptors dynamically fit gene repertoire sizes. Mol. Biol. Evol. 31 3216-27 PubMed GONUTS page

[PMID:21873635-4] 4.0 ^4.1 ^4.2 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

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CHICK:Q2AB83

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