CHICK:B6UVA0

Species (Taxon ID)	Gallus gallus (Chicken). (9031)
Gene Name(s)	No Information Provided.
Protein Name(s)	DRD4 (ECO:0000313 with EMBL:ACJ06720.1) Dopamine receptor D4 (ECO:0000313 with EMBL:BAP27901.1) Uncharacterized protein (ECO:0000313 with Ensembl:ENSGALP00000008142)
External Links
UniProt	B6UVA0
EMBL	AADN03004595 FJ217173 AB699005 AB699006 AB699007 AB699008 AB699009 AB699010 AB699011 AB699012 AB699018 AB699022 AB699023 AB699027 AB699028 AB699029 AB699030 AB699031
RefSeq	NP_001136321.1
UniGene	Gga.34426
STRING	9031.ENSGALP00000008142
Ensembl	ENSGALT00000008156
GeneID	423016
KEGG	gga:423016
CTD	1815
eggNOG	NOG256691
GeneTree	ENSGT00770000120457
HOGENOM	HOG000239242
HOVERGEN	HBG106962
KO	K04147
OMA	KFFKKCF
OrthoDB	EOG769ZMG
PhylomeDB	B6UVA0
TreeFam	TF334382
Reactome	REACT_250593 REACT_253620
NextBio	20825553
PRO	PR:B6UVA0
Proteomes	UP000000539
GO	GO:0005887 GO:0035240 GO:0001591 GO:0008144 GO:0000187 GO:0007195 GO:0008344 GO:0050482 GO:0048148 GO:0042596 GO:0007194 GO:0050709 GO:1901386 GO:0032417 GO:0042752 GO:0042053 GO:0060080 GO:0001975 GO:0034776
InterPro	IPR002185 IPR000929 IPR000276 IPR017452
PANTHER	PTHR24249:SF37
Pfam	PF00001
PRINTS	PR00569 PR00242 PR00237
PROSITE	PS00237 PS50262

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Notes	Status
enables	GO:0030594	neurotransmitter receptor activity	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000664111 RGD:71034	F	Seeded From UniProt	complete
part_of	GO:0030425	dendrite	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000664111 RGD:2342 RGD:2343 RGD:2518 RGD:2522 RGD:2851 RGD:61800 RGD:61801 RGD:620023 RGD:62044 RGD:71034	C	Seeded From UniProt	complete
involved_in	GO:0007268	chemical synaptic transmission	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000664111 RGD:2830 RGD:2846	P	Seeded From UniProt	complete
involved_in	GO:0007187	G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000664111 RGD:2851 RGD:62044	P	Seeded From UniProt	complete
part_of	GO:0005887	integral component of plasma membrane	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0000037 PANTHER:PTN000664111 RGD:2343 UniProtKB:P08172 UniProtKB:P08908 UniProtKB:P21917 UniProtKB:P28221 UniProtKB:P28222 UniProtKB:P28335 UniProtKB:P28566 UniProtKB:P30546 UniProtKB:P30939 WB:WBGene00001519	C	Seeded From UniProt	complete
enables	GO:0004993	G protein-coupled serotonin receptor activity	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0004168 FB:FBgn0004573 FB:FBgn0087012 FB:FBgn0263116 MGI:MGI:109323 MGI:MGI:96273 MGI:MGI:96274 MGI:MGI:96276 MGI:MGI:96281 MGI:MGI:96284 PANTHER:PTN000664111 RGD:2845 RGD:2846 RGD:2848 RGD:2850 RGD:2851 RGD:61800 RGD:62044 RGD:62388 RGD:71034 UniProtKB:A0A0B4KFU6 UniProtKB:P08908 UniProtKB:P28221 UniProtKB:P28222 UniProtKB:P28223 UniProtKB:P28335 UniProtKB:P28566 UniProtKB:P30939 UniProtKB:P41595 UniProtKB:P47898 UniProtKB:Q13639 WB:WBGene00004776 WB:WBGene00004779	F	Seeded From UniProt	complete
enables	GO:0004930	G protein-coupled receptor activity	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000664111 RGD:2518	F	Seeded From UniProt	complete
involved_in	GO:0098664	G protein-coupled serotonin receptor signaling pathway	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0004993	P	Seeded From UniProt	complete
part_of	GO:0098794	postsynapse	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0060080	C	Seeded From UniProt	complete
involved_in	GO:1901386	negative regulation of voltage-gated calcium channel activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P21917 ensembl:ENSP00000176183	P	Seeded From UniProt	complete
enables	GO:0051380	norepinephrine binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P21917 ensembl:ENSP00000176183	F	Seeded From UniProt	complete
enables	GO:0051379	epinephrine binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P21917 ensembl:ENSP00000176183	F	Seeded From UniProt	complete
involved_in	GO:0050709	negative regulation of protein secretion	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P21917 ensembl:ENSP00000176183	P	Seeded From UniProt	complete
involved_in	GO:0050482	arachidonic acid secretion	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P21917 ensembl:ENSP00000176183	P	Seeded From UniProt	complete
enables	GO:0042802	identical protein binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P21917 ensembl:ENSP00000176183	F	Seeded From UniProt	complete
enables	GO:0035240	dopamine binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P21917 ensembl:ENSP00000176183	F	Seeded From UniProt	complete
involved_in	GO:0034776	response to histamine	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P21917 ensembl:ENSP00000176183	P	Seeded From UniProt	complete
involved_in	GO:0033674	positive regulation of kinase activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P21917 ensembl:ENSP00000176183	P	Seeded From UniProt	complete
involved_in	GO:0032417	positive regulation of sodium:proton antiporter activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P21917 ensembl:ENSP00000176183	P	Seeded From UniProt	complete
enables	GO:0017124	SH3 domain binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P21917 ensembl:ENSP00000176183	F	Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P21917 ensembl:ENSP00000176183	C	Seeded From UniProt	complete
enables	GO:0008144	drug binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P21917 ensembl:ENSP00000176183	F	Seeded From UniProt	complete
involved_in	GO:0007212	dopamine receptor signaling pathway	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P21917 ensembl:ENSP00000176183	P	Seeded From UniProt	complete
involved_in	GO:0007195	adenylate cyclase-inhibiting dopamine receptor signaling pathway	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P21917 ensembl:ENSP00000176183	P	Seeded From UniProt	complete
part_of	GO:0005887	integral component of plasma membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P21917 ensembl:ENSP00000176183	C	Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P21917 ensembl:ENSP00000176183	C	Seeded From UniProt	complete
enables	GO:0004952	dopamine neurotransmitter receptor activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P21917 ensembl:ENSP00000176183	F	Seeded From UniProt	complete
enables	GO:0001591	dopamine neurotransmitter receptor activity, coupled via Gi/Go	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P21917 ensembl:ENSP00000176183	F	Seeded From UniProt	complete
involved_in	GO:0000187	activation of MAPK activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P21917 ensembl:ENSP00000176183	P	Seeded From UniProt	complete
involved_in	GO:0099149	regulation of postsynaptic neurotransmitter receptor internalization	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P51436 ensembl:ENSMUSP00000026569	P	Seeded From UniProt	complete
part_of	GO:0098978	glutamatergic synapse	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P51436 ensembl:ENSMUSP00000026569	C	Seeded From UniProt	complete
involved_in	GO:0060080	inhibitory postsynaptic potential	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P51436 ensembl:ENSMUSP00000026569	P	Seeded From UniProt	complete
involved_in	GO:0048148	behavioral response to cocaine	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P51436 ensembl:ENSMUSP00000026569	P	Seeded From UniProt	complete
involved_in	GO:0042752	regulation of circadian rhythm	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P51436 ensembl:ENSMUSP00000026569	P	Seeded From UniProt	complete
involved_in	GO:0042596	fear response	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P51436 ensembl:ENSMUSP00000026569	P	Seeded From UniProt	complete
involved_in	GO:0042053	regulation of dopamine metabolic process	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P51436 ensembl:ENSMUSP00000026569	P	Seeded From UniProt	complete
involved_in	GO:0008344	adult locomotory behavior	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P51436 ensembl:ENSMUSP00000026569	P	Seeded From UniProt	complete
involved_in	GO:0007195	adenylate cyclase-inhibiting dopamine receptor signaling pathway	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P51436 ensembl:ENSMUSP00000026569	P	Seeded From UniProt	complete
involved_in	GO:0001975	response to amphetamine	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P51436 ensembl:ENSMUSP00000026569	P	Seeded From UniProt	complete
enables	GO:0001591	dopamine neurotransmitter receptor activity, coupled via Gi/Go	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P51436 ensembl:ENSMUSP00000026569	F	Seeded From UniProt	complete
enables	GO:0004930	G protein-coupled receptor activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000276	F	Seeded From UniProt	complete
enables	GO:0004952	dopamine neurotransmitter receptor activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR002185	F	Seeded From UniProt	complete
part_of	GO:0005887	integral component of plasma membrane	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR002185	C	Seeded From UniProt	complete
involved_in	GO:0007186	G protein-coupled receptor signaling pathway	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000276	P	Seeded From UniProt	complete
involved_in	GO:0007195	adenylate cyclase-inhibiting dopamine receptor signaling pathway	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR002185	P	Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000276 InterPro:IPR017452	C	Seeded From UniProt	complete
involved_in	GO:0007186	G protein-coupled receptor signaling pathway	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0297	P	Seeded From UniProt	complete
involved_in	GO:0007165	signal transduction	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0807	P	Seeded From UniProt	complete
enables	GO:0004930	G protein-coupled receptor activity	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0297	F	Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0812	C	Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0472	C	Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 ^1.2 ^1.3 ^1.4 ^1.5 ^1.6 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:21873635-1] 1.0 ^1.1 ^1.2 ^1.3 ^1.4 ^1.5 ^1.6 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

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CHICK:B6UVA0

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