User:Alemus

My Annotations

Status	Page	Date/Time	GO Term (Aspect)	Reference	Evidence	Notes	Links
updatedbyinstructor	9HEPC:Q8V7L6	2013-02-09 21:38:24 CST	GO:0052040 modulation by symbiont of host programmed cell death (P)	PMID:19951438	ECO:0000314 direct assay evidence used in manual assertion	Figure 5. Shows that zVAD inhibits all other proteins that use caspase to induce apoptosis in hepatic cells, but it only partially inhibits the core protein, meaning that the core protein induces apoptosis independently from caspase.	challenge
updatedbyinstructor	HPV16:VE2	2013-02-09 23:12:33 CST	GO:0044163 host cytoskeleton (C)	PMID:15020762	ECO:0000314 direct assay evidence used in manual assertion	Figure 1 C shows that HPV 16 and E2 protein is involved in binding to mitotic spindles and pulling apart replicating DNA strands	challenge
updatedbyinstructor	HPV11:D7GMV3	2013-02-09 23:24:37 CST	GO:0044163 host cytoskeleton (C)	PMID:15020762	ECO:0000314 direct assay evidence used in manual assertion	Figure 1A/B & Fig 2	challenge
updatedbyinstructor	HPV18:VE2	2013-02-09 23:33:03 CST	GO:0044163 host cytoskeleton (C)	PMID:15020762	ECO:0000314 direct assay evidence used in manual assertion	Figure 1D shows that E2 protein from HPV 18 binds to mitotic spindles and helps pull apart DNA strands as shown in the 3rd overlap of DNA, E2 and mitotic spindles.	challenge
updatedbyinstructor	HPV16:VE5	2013-02-10 00:14:31 CST	GO:0033668 negative regulation by symbiont of host apoptotic process (P)	PMID:11739687	ECO:0000315 mutant phenotype evidence used in manual assertion	Figure 2 shows a TUNNEL in parts A and B where E2 has kept HFKs from going under apoptosis after being exposed to UV. L(16E5)SN-infected keratinocytes were exposed to 0 (A) and 400 (B) J of UV light, the cells were stained with DAPI. this happens by E5 enhancing EGFR activation.	challenge
requireschanges	HUMAN:RGS10	2013-02-10 01:15:50 CST	GO:0005096 GTPase activator activity (F)	PMID:10791963	ECO:0000314 direct assay evidence used in manual assertion	Figure 3 shows RGS16 activates GFP by turning off Galpha and Gbeta quicker,as seen in the overlay (yellow) in flourescence picture shows the activation of GFP.	challenge

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unacceptable:0
requires_changes:1
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Annotations challenged by Alemus

Status	Author,Group	Page	GO Term (Aspect)	Reference	Evidence	Links	Page history
updatedbyinstructor	Sbutler, Team Thundercats Ho!	HUMAN:KSYK	GO:0006468 - protein phosphorylation (P)	PMID:17681949	ECO:0000314 direct assay evidence used in manual assertion	challenge	C: 2
unacceptable	Sanwar, Team Racer X	MOUSE:FFAR4	GO:0008289 - lipid binding (F)	PMID:21868624	ECO:0000269 experimental evidence used in manual assertion	challenge	C: 3
unacceptable	Rgarcia, Team Chalupa Batman	HUMAN:NS1BP	GO:0005634 - nucleus (C)	PMID:2969057	ECO:0000304 author statement supported by traceable reference used in manual assertion	challenge	C: 5
unacceptable	Rgarcia, Team Chalupa Batman	HUMAN:DYH8	GO:0030286 - dynein complex (C)	PMID:22863569	ECO:0000314 direct assay evidence used in manual assertion	challenge	C: 5
unacceptable	Rgarcia, Team Chalupa Batman	HUMAN:ACTS	GO:0016049 - cell growth (P)	PMID:21900491	ECO:0000314 direct assay evidence used in manual assertion	challenge	C: 1

0 annotations fixed by Alemus

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