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9HEPC:Q8V7L6

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Species (Taxon ID) Hepatitis C virus. (11103)
Gene Name(s) core (ECO:0000313 with EMBL:BAB83452.1)
Protein Name(s) Core protein (ECO:0000313 with EMBL:BAB83452.1)
External Links
UniProt Q8V7L6
EMBL AB062258
ProteinModelPortal Q8V7L6
euHCVdb AB062258
GO GO:0019028
GO:0005198
GO:0052040
InterPro IPR002521
IPR002522
Pfam PF01543
PF01542

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0052040

modulation by symbiont of host programmed cell death

PMID:19951438[1]

ECO:0000314

P

Figure 5. Shows that zVAD inhibits all other proteins that use caspase to induce apoptosis in hepatic cells, but it only partially inhibits the core protein, meaning that the core protein induces apoptosis independently from caspase.

complete
CACAO 6489

involved_in

GO:0052040

modulation by symbiont of host programmed cell death

PMID:19951438[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0005198

structural molecule activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002521
InterPro:IPR002522

F

Seeded From UniProt

complete

part_of

GO:0019028

viral capsid

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002522

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Berg, CP et al. (2009) Hepatitis C virus core protein induces apoptosis-like caspase independent cell death. Virol. J. 6 213 PubMed GONUTS page