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HUMAN:DYH8

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Species (Taxon ID) Homo sapiens (Human). (9606)
Gene Name(s) DNAH8
Protein Name(s) Dynein heavy chain 8, axonemal

Axonemal beta dynein heavy chain 8 Ciliary dynein heavy chain 8

External Links
UniProt Q96JB1
EMBL AF356519
AL035690
AL034345
AL035555
AL353700
AL035690
AL034345
AL035555
AL353700
AL391415
AL035555
AL034345
AL035690
AL353700
AL035555
AL034345
AL353700
AL391415
AL035555
AL034345
AL035690
AL353700
AL391415
AL353700
AL034345
AL035555
AL035690
AL353700
AL034345
AL035555
AL391415
AL353700
AL034345
AL035555
AL035690
AL391415
AL391415
AL034345
AL035555
AL353700
AL391415
AL034345
AL035555
AL035690
AL353700
AL034345
AL035555
AL035690
AL353700
AL034345
AL034345
AL035555
AL353700
AL391415
AL034345
AL035555
AL035690
AL353700
AL391415
Z83806
AJ132091
RefSeq NP_001193856.1
UniGene Hs.520106
Hs.686107
ProteinModelPortal Q96JB1
SMR Q96JB1
STRING 9606.ENSP00000352312
PhosphoSite Q96JB1
DMDM 124007137
MaxQB Q96JB1
PaxDb Q96JB1
PRIDE Q96JB1
Ensembl ENST00000359357
GeneID 1769
KEGG hsa:1769
UCSC uc003ooe.2
CTD 1769
GeneCards GC06P038685
H-InvDB HIX0033271
HGNC HGNC:2952
HPA HPA028447
HPA030108
MIM 603337
neXtProt NX_Q96JB1
PharmGKB PA27405
eggNOG COG5245
GeneTree ENSGT00760000118964
HOVERGEN HBG005543
InParanoid Q96JB1
KO K10408
PhylomeDB Q96JB1
TreeFam TF316836
GenomeRNAi 1769
NextBio 7201
PRO PR:Q96JB1
Proteomes UP000005640
Bgee Q96JB1
CleanEx HS_DNAH8
ExpressionAtlas Q96JB1
Genevestigator Q96JB1
GO GO:0005858
GO:0005874
GO:0005524
GO:0016887
GO:0003777
GO:0001539
GO:0008152
GO:0007018
Gene3D 3.40.50.300
InterPro IPR003593
IPR011704
IPR026983
IPR024743
IPR024317
IPR004273
IPR013594
IPR013602
IPR027417
PANTHER PTHR10676
Pfam PF07728
PF12780
PF08385
PF08393
PF03028
PF12777
SMART SM00382
SUPFAM SSF52540

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0030286

dynein complex

PMID:22863569[1]

ECO:0000314

C

Figure 3.b shows cytoplasmic dynein motors.

complete
CACAO 6463

part_of

GO:0030286

dynein complex

PMID:22863569[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005858

axonemal dynein complex

PMID:9373155[2]

ECO:0000303

author statement without traceable support used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0003777

microtubule motor activity

PMID:9373155[2]

ECO:0000303

author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0060285

cilium-dependent cell motility

PMID:9373155[2]

ECO:0000303

author statement without traceable support used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0051959

dynein light intermediate chain binding

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:103147
PANTHER:PTN000743491
RGD:71042
UniProtKB:Q14204

F

Seeded From UniProt

complete

enables

GO:0045505

dynein intermediate chain binding

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000743491
dictyBase:DDB_G0276355

F

Seeded From UniProt

complete

enables

GO:0045503

dynein light chain binding

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000743491
UniProtKB:A8I3X6
UniProtKB:A8I5C3
UniProtKB:A8ISA6
UniProtKB:A8IV22
UniProtKB:A8JDH8
UniProtKB:Q9SMH5

F

Seeded From UniProt

complete

involved_in

GO:0036158

outer dynein arm assembly

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000840538
UniProtKB:Q8TE73

P

Seeded From UniProt

complete

part_of

GO:0036157

outer dynein arm

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000840538
UniProtKB:Q8TE73

C

Seeded From UniProt

complete

part_of

GO:0030286

dynein complex

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0261797
PANTHER:PTN000743491
UniProtKB:Q96JB1
UniProtKB:Q9SMH5

C

Seeded From UniProt

complete

enables

GO:0008569

ATP-dependent microtubule motor activity, minus-end-directed

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000743491
SGD:S000001762
UniProtKB:A8JDH8
UniProtKB:P45444
UniProtKB:Q14204
UniProtKB:Q8NCM8

F

Seeded From UniProt

complete

involved_in

GO:0007018

microtubule-based movement

PMID:21873635[3]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0261797
PANTHER:PTN000743491

P

Seeded From UniProt

complete

enables

GO:0003777

microtubule motor activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR004273
InterPro:IPR026983

F

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR035699

F

Seeded From UniProt

complete

involved_in

GO:0007018

microtubule-based movement

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR004273
InterPro:IPR026983

P

Seeded From UniProt

complete

part_of

GO:0030286

dynein complex

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR004273

C

Seeded From UniProt

complete

part_of

GO:0030286

dynein complex

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0243

C

Seeded From UniProt

complete

part_of

GO:0005856

cytoskeleton

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0206

C

Seeded From UniProt

complete

enables

GO:0003774

motor activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0243

F

Seeded From UniProt

complete

part_of

GO:0005874

microtubule

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0493

C

Seeded From UniProt

complete

part_of

GO:0042995

cell projection

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0966

C

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963

C

Seeded From UniProt

complete

part_of

GO:0005929

cilium

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0969

C

Seeded From UniProt

complete

enables

GO:0000166

nucleotide binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0547

F

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0067

F

Seeded From UniProt

complete

edit table

Notes

References

See Help:References for how to manage references in GONUTS.

  1. ↑ 1.0 1.1 Roberts, AJ et al. (2012) ATP-driven remodeling of the linker domain in the dynein motor. Structure 20 1670-80 PubMed GONUTS page
  2. ↑ 2.0 2.1 2.2 Neesen, J et al. (1997) Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene. Gene 200 193-202 PubMed GONUTS page
  3. ↑ 3.0 3.1 3.2 3.3 3.4 3.5 3.6 3.7 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
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