Category:GO:0038084 ! vascular endothelial growth factor signaling pathway

name: vascular endothelial growth factor signaling pathway
namespace: biological_process
def: "The series of molecular signals initiated by vascular endothelial growth factor (VEGF) binding its receptor on the surface of the target cell, and ending with the regulation of a downstream cellular process, e.g. transcription." [GOC:signaling, PMID:17470632]
comment: In GO, a gene product with 'vascular endothelial growth factor-activated receptor activity ; GO:0005021' necessarily binds VEGF to transduce a signal. To represent cross-talk between ligands and receptors, signaling pathways in GO are starting to be named after the receptor and/or the signal. GO:0038084 is for annotation of any pathway in which the ligand VEGF binds and activates any cell surface receptor (VEGFR, PDGFR etc.). For annotation of signaling pathways where a VEGFR binds one of its physiological ligands (VEGF or an alternative growth factor), consider 'vascular endothelial growth factor receptor signaling pathway ; GO:0048010'.
synonym: "vascular endothelial growth factor signalling pathway" EXACT [GOC:bf]
synonym: "VEGF signaling" EXACT [GOC:bf]
synonym: "VEGF-activated signaling pathway" EXACT [GOC:bf]
is_a: GO:0007169 ! cell surface receptor protein tyrosine kinase signaling pathway
relationship: part_of: GO:0035924 ! cellular response to vascular endothelial growth factor stimulus

AmiGO <GOterm>GO:0038084</GOterm>
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