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CHICK:NRP1

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Species (Taxon ID) Gallus gallus (Chicken). (9031)
Gene Name(s) NRP1 (synonyms: NRP)
Protein Name(s) Neuropilin-1

A5 protein

External Links
UniProt P79795
EMBL D45416
RefSeq NP_990113.1
UniGene Gga.4032
ProteinModelPortal P79795
SMR P79795
STRING 9031.ENSGALP00000011550
PaxDb P79795
PRIDE P79795
GeneID 395560
KEGG gga:395560
CTD 8829
eggNOG NOG150941
HOGENOM HOG000039978
HOVERGEN HBG000502
InParanoid P79795
KO K06724
PhylomeDB P79795
NextBio 20815635
PRO PR:P79795
Proteomes UP000000539
GO GO:0016021
GO:0008201
GO:0046872
GO:0017154
GO:0005021
GO:0001525
GO:0007411
GO:0007155
GO:0035767
GO:0009887
GO:0048010
Gene3D 2.60.120.260
2.60.120.290
InterPro IPR000421
IPR013320
IPR000859
IPR008979
IPR000998
IPR014648
IPR022579
IPR027146
PANTHER PTHR10127:SF616
Pfam PF00431
PF11980
PF00754
PF00629
PIRSF PIRSF036960
PRINTS PR00020
SMART SM00042
SM00231
SM00137
SUPFAM SSF49785
SSF49854
SSF49899
PROSITE PS01180
PS01285
PS01286
PS50022
PS00740
PS50060

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0051491

positive regulation of filopodium assembly

PMID:16959234[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

  • occurs_in:(CL:0000008)
  • occurs_in:(UBERON:0003066)

Seeded From UniProt

complete

involved_in

GO:0022035

rhombomere cell migration

PMID:16959234[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005623

cell

PMID:25183873[2]

ECO:0000314

direct assay evidence used in manual assertion

C

  • part_of:(UBERON:0006788)
  • part_of:(UBERON:0006787)

Seeded From UniProt

complete

involved_in

GO:0048729

tissue morphogenesis

PMID:25183873[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

occurs_in:(UBERON:0001945)

Seeded From UniProt

complete

part_of

GO:0030424

axon

PMID:7601310[3]

ECO:0000314

direct assay evidence used in manual assertion

C

  • part_of:(CL:0000100)
  • part_of:(UBERON:0002260)|part_of:(CL:0000100)
  • part_of:(UBERON:0005375)

Seeded From UniProt

complete

part_of

GO:0070852

cell body fiber

PMID:7601310[3]

ECO:0000314

direct assay evidence used in manual assertion

C

part_of:(UBERON:0001795)|part_of:(UBERON:0001791)|part_of:(UBERON:0004904)|part_of:(UBERON:0006238)|part_of:(UBERON:0007622)|part_of:(UBERON:0001783)|part_of:(CL:0000134)|part_of:(UBERON:0035570)|part_of:(UBERON:0002258)|part_of:(UBERON:0000044)

Seeded From UniProt

complete

involved_in

GO:0098743

cell aggregation

PMID:7601310[3]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

PMID:7601310[3]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0044295

axonal growth cone

PMID:18039974[4]

ECO:0000314

direct assay evidence used in manual assertion

C

  • part_of:(UBERON:0010405)
  • part_of:(CL:0000100)|part_of:(UBERON:0004059)
  • part_of:(CL:0000100)

Seeded From UniProt

complete

part_of

GO:0043679

axon terminus

PMID:18039974[4]

ECO:0000314

direct assay evidence used in manual assertion

C

  • part_of:(UBERON:0010405)
  • part_of:(CL:0000100)|part_of:(UBERON:0004059)
  • part_of:(CL:0000100)

Seeded From UniProt

complete

part_of

GO:0032584

growth cone membrane

PMID:18039974[4]

ECO:0000314

direct assay evidence used in manual assertion

C

  • part_of:(UBERON:0010405)
  • part_of:(CL:0000100)|part_of:(UBERON:0004059)
  • part_of:(CL:0000100)

Seeded From UniProt

complete

part_of

GO:0005623

cell

PMID:16959234[1]

ECO:0000314

direct assay evidence used in manual assertion

C

  • part_of:(UBERON:0001049)
  • part_of:(CL:0000008)|part_of:(UBERON:0010257)
  • part_of:(CL:0000008)|part_of:(UBERON:0010256)
  • part_of:(CL:0000008)|part_of:(UBERON:0011210)
  • part_of:(CL:0000008)

Seeded From UniProt

complete

involved_in

GO:0001525

angiogenesis

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR014648
InterPro:IPR027146

P

Seeded From UniProt

complete

enables

GO:0005021

vascular endothelial growth factor-activated receptor activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR014648
InterPro:IPR027146

F

Seeded From UniProt

complete

involved_in

GO:0007411

axon guidance

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR014648
InterPro:IPR027146

P

Seeded From UniProt

complete

involved_in

GO:0009887

animal organ morphogenesis

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR027146

P

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000998

C

Seeded From UniProt

complete

enables

GO:0017154

semaphorin receptor activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR014648
InterPro:IPR027146

F

Seeded From UniProt

complete

enables

GO:0019838

growth factor binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR027146

F

Seeded From UniProt

complete

involved_in

GO:0035767

endothelial cell chemotaxis

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR027146

P

Seeded From UniProt

complete

involved_in

GO:0038084

vascular endothelial growth factor signaling pathway

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR014648

P

Seeded From UniProt

complete

involved_in

GO:0048010

vascular endothelial growth factor receptor signaling pathway

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR027146

P

Seeded From UniProt

complete

involved_in

GO:0071526

semaphorin-plexin signaling pathway

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR027146

P

Seeded From UniProt

complete

involved_in

GO:0007275

multicellular organism development

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0217

P

Seeded From UniProt

complete

involved_in

GO:0030154

cell differentiation

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0221

P

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

involved_in

GO:0001525

angiogenesis

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0037

P

Seeded From UniProt

complete

enables

GO:0008201

heparin binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0358

F

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

involved_in

GO:0007155

cell adhesion

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0130

P

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472
UniProtKB-SubCell:SL-0162

C

Seeded From UniProt

complete

involved_in

GO:0007399

nervous system development

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0524

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 McLennan, R & Kulesa, PM (2007) In vivo analysis reveals a critical role for neuropilin-1 in cranial neural crest cell migration in chick. Dev. Biol. 301 227-39 PubMed GONUTS page
  2. 2.0 2.1 Watanabe, Y et al. (2014) NRP1-mediated Sema3A signals coordinate laminar formation in the developing chick optic tectum. Development 141 3572-82 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 Takagi, S et al. (1995) Expression of a cell adhesion molecule, neuropilin, in the developing chick nervous system. Dev. Biol. 170 207-22 PubMed GONUTS page
  4. 4.0 4.1 4.2 Moret, F et al. (2007) Semaphorin and neuropilin co-expression in motoneurons sets axon sensitivity to environmental semaphorin sources during motor axon pathfinding. Development 134 4491-501 PubMed GONUTS page