HUMAN:NRP1

Species (Taxon ID)	Homo sapiens (Human). (9606)
Gene Name(s)	NRP1 (synonyms: NRP, VEGF165R)
Protein Name(s)	Neuropilin-1 Vascular endothelial cell growth factor 165 receptor
External Links
UniProt	O14786
EMBL	AF018956 AF016050 AF145712 BT006995 BX510902 EU332859 AL353600 AL121748 AL353600 AL121748 AL121748 AL353600 AL121748 AL353600 CH471072 CH471072 BC007533 BC007737
CCDS	CCDS31179.1 CCDS31180.1 CCDS7177.1
RefSeq	NP_001019799.1 NP_001019800.1 NP_003864.4
UniGene	Hs.131704 Hs.653996
PDB	1KEX 2QQI 2QQM 2QQN 3I97 4DEQ
PDBsum	1KEX 2QQI 2QQM 2QQN 3I97 4DEQ
ProteinModelPortal	O14786
SMR	O14786
BioGrid	114356
DIP	DIP-5743N
IntAct	O14786
MINT	MINT-2834207
STRING	9606.ENSP00000265371
BindingDB	O14786
ChEMBL	CHEMBL5174
DrugBank	DB00039 DB04895
PhosphoSite	O14786
MaxQB	O14786
PaxDb	O14786
PRIDE	O14786
DNASU	8829
Ensembl	ENST00000265371 ENST00000374821 ENST00000374822 ENST00000374867
GeneID	8829
KEGG	hsa:8829
UCSC	uc001iwx.4 uc001ixa.2
CTD	8829
GeneCards	GC10M033466
HGNC	HGNC:8004
HPA	CAB004511 HPA030278
MIM	602069
neXtProt	NX_O14786
PharmGKB	PA31783
eggNOG	NOG150941
GeneTree	ENSGT00760000119073
HOVERGEN	HBG000502
InParanoid	O14786
KO	K06724
OMA	GWGSHKT
PhylomeDB	O14786
TreeFam	TF316506
Reactome	REACT_12473 REACT_19199 REACT_19236 REACT_19279 REACT_22272 REACT_22292
ChiTaRS	NRP1
EvolutionaryTrace	O14786
GeneWiki	Neuropilin_1
GenomeRNAi	8829
NextBio	33134
PMAP-CutDB	B0LPG9
PRO	PR:O14786
Proteomes	UP000005640
Bgee	O14786
CleanEx	HS_NRP1
ExpressionAtlas	O14786
Genevestigator	O14786
GO	GO:0030424 GO:0009986 GO:0031410 GO:0005829 GO:0005769 GO:0005615 GO:0005925 GO:0030426 GO:0016021 GO:0005883 GO:0043025 GO:0005886 GO:0043235 GO:0002116 GO:0097443 GO:0015026 GO:0019955 GO:0019838 GO:0008201 GO:0046872 GO:0017154 GO:0038085 GO:0005021 GO:0001525 GO:0060978 GO:0048844 GO:0048846 GO:0007411 GO:0007413 GO:0060385 GO:0021785 GO:0007155 GO:0002042 GO:0007267 GO:0035729 GO:0035924 GO:0071679 GO:0060982 GO:0016358 GO:0060666 GO:0035767 GO:0097102 GO:0021612 GO:0021828 GO:0048012 GO:0048843 GO:2001237 GO:0043524 GO:0021675 GO:1901166 GO:0001764 GO:0009887 GO:0001569 GO:0048008 GO:0050918 GO:0048842 GO:0060301 GO:0010595 GO:0001938 GO:0070374 GO:0050731 GO:1902336 GO:0014911 GO:1902946 GO:0090259 GO:0060627 GO:0061441 GO:0009611 GO:0061299 GO:0031290 GO:0071526 GO:1902287 GO:1902285 GO:0007165 GO:0002040 GO:0061549 GO:0097490 GO:0097491 GO:0021637 GO:0048010 GO:0038190 GO:1902378
Gene3D	2.60.120.260 2.60.120.290
InterPro	IPR000421 IPR013320 IPR000859 IPR008979 IPR000998 IPR014648 IPR022579 IPR027146
PANTHER	PTHR10127:SF616
Pfam	PF00431 PF11980 PF00754 PF00629
PIRSF	PIRSF036960
PRINTS	PR00020
SMART	SM00042 SM00231 SM00137
SUPFAM	SSF49785 SSF49854 SSF49899
PROSITE	PS01180 PS01285 PS01286 PS50022 PS00740 PS50060

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
part_of	GO:0043005	neuron projection	PMID:22683681^[1]	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P97333	C	part_of:(UBERON:0004040)\|part_of:(UBERON:0005343)	Seeded From UniProt	complete
involved_in	GO:0150020	basal dendrite arborization	PMID:22683681^[1]	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P97333	P	occurs_in:(CL:0002609) occurs_in:(UBERON:0005394)	Seeded From UniProt	complete
involved_in	GO:0150018	basal dendrite development	PMID:22683681^[1]	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P97333	P	occurs_in:(CL:0002609) occurs_in:(UBERON:0005391)\|occurs_in:(CL:0002609) occurs_in:(UBERON:0005392)	Seeded From UniProt	complete
part_of	GO:0005925	focal adhesion	PMID:24863063^[2]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0031532	actin cytoskeleton reorganization	PMID:24863063^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	part_of:(GO:0007229) part_of:(GO:0038189) occurs_in:(CL:0000115)	Seeded From UniProt	complete
involved_in	GO:0007229	integrin-mediated signaling pathway	PMID:24863063^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	occurs_in:(CL:0000115)	Seeded From UniProt	complete
involved_in	GO:0038189	neuropilin signaling pathway	PMID:24863063^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	occurs_in:(CL:0000115)	Seeded From UniProt	complete
involved_in	GO:0006930	substrate-dependent cell migration, cell extension	PMID:24863063^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	part_of:(GO:0007229) part_of:(GO:0038189) occurs_in:(CL:0000115)	Seeded From UniProt	complete
involved_in	GO:0051894	positive regulation of focal adhesion assembly	PMID:24863063^[2]	ECO:0000314	direct assay evidence used in manual assertion		P	part_of:(GO:0007229) part_of:(GO:0038189)	Seeded From UniProt	complete
involved_in	GO:0043542	endothelial cell migration	PMID:24863063^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	part_of:(GO:0007229) part_of:(GO:0038189)	Seeded From UniProt	complete
involved_in	GO:2000251	positive regulation of actin cytoskeleton reorganization	PMID:24863063^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0034446	substrate adhesion-dependent cell spreading	PMID:24863063^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	part_of:(GO:0007229) part_of:(GO:0038189) part_of:(CL:0000115)	Seeded From UniProt	complete
involved_in	GO:0042327	positive regulation of phosphorylation	PMID:24863063^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	has_regulation_target:(UniProtKB:P27361) part_of:(GO:0007229) part_of:(GO:0038189) positively_regulates:(GO:0043542) causally_upstream_of:(GO:0070371)	Seeded From UniProt	complete
involved_in	GO:0042327	positive regulation of phosphorylation	PMID:24863063^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	has_regulation_target:(UniProtKB:P27361) part_of:(GO:0038190) causally_upstream_of:(GO:0070371)	Seeded From UniProt	complete
involved_in	GO:0038190	VEGF-activated neuropilin signaling pathway	PMID:24863063^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	causally_upstream_of:(GO:0070371)	Seeded From UniProt	complete
involved_in	GO:0003148	outflow tract septum morphogenesis	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P97333	P	occurs_in:(UBERON:0004699) part_of:(GO:0071526)	Seeded From UniProt	complete
involved_in	GO:0051491	positive regulation of filopodium assembly	PMID:26051942^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	part_of:(GO:0038189) part_of:(GO:0007229)	Seeded From UniProt	complete
involved_in	GO:0038189	neuropilin signaling pathway	PMID:26051942^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0032489	regulation of Cdc42 protein signal transduction	PMID:26051942^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	part_of:(GO:0038189) part_of:(GO:0007229)	Seeded From UniProt	complete
involved_in	GO:0051496	positive regulation of stress fiber assembly	PMID:26051942^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	part_of:(GO:0038189) part_of:(GO:0007229)	Seeded From UniProt	complete
involved_in	GO:2000251	positive regulation of actin cytoskeleton reorganization	PMID:26051942^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	part_of:(GO:0038189) part_of:(GO:0007229)	Seeded From UniProt	complete
involved_in	GO:0097475	motor neuron migration	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P97333	P		Seeded From UniProt	complete
part_of	GO:0005925	focal adhesion	PMID:21423176^[4]	ECO:0007005	high throughput direct assay evidence used in manual assertion		C	part_of:(CL:0000057)	Seeded From UniProt	complete
part_of	GO:0005615	extracellular space	PMID:16502470^[5]	ECO:0007005	high throughput direct assay evidence used in manual assertion		C	part_of:(UBERON:0001914)	Seeded From UniProt	complete
involved_in	GO:1902946	protein localization to early endosome	PMID:23639442^[6]	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P97333	P		Seeded From UniProt	complete
involved_in	GO:1902336	positive regulation of retinal ganglion cell axon guidance	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P97333	P		Seeded From UniProt	complete
involved_in	GO:1902285	semaphorin-plexin signaling pathway involved in neuron projection guidance	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P97333	P		Seeded From UniProt	complete
involved_in	GO:1901166	neural crest cell migration involved in autonomic nervous system development	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P97333	P		Seeded From UniProt	complete
involved_in	GO:0097491	sympathetic neuron projection guidance	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P97333	P		Seeded From UniProt	complete
involved_in	GO:0097490	sympathetic neuron projection extension	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P97333	P		Seeded From UniProt	complete
part_of	GO:0097443	sorting endosome	PMID:23639442^[6]	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P97333	C		Seeded From UniProt	complete
involved_in	GO:0097102	endothelial tip cell fate specification	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P97333	P	happens_during:(GO:0030902) occurs_in:(CL:0000704)	Seeded From UniProt	complete
involved_in	GO:0090259	regulation of retinal ganglion cell axon guidance	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P97333	P		Seeded From UniProt	complete
involved_in	GO:0071679	commissural neuron axon guidance	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P97333	P	occurs_in:(CL:0000740) occurs_in:(UBERON:0000959)	Seeded From UniProt	complete
involved_in	GO:0071526	semaphorin-plexin signaling pathway	PMID:19909241^[7]	ECO:0000303	author statement without traceable support used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0070374	positive regulation of ERK1 and ERK2 cascade	PMID:23639442^[6]	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P97333	P		Seeded From UniProt	complete
involved_in	GO:0061549	sympathetic ganglion development	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P97333	P		Seeded From UniProt	complete
involved_in	GO:0061299	retina vasculature morphogenesis in camera-type eye	PMID:24401374^[8]	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P97333	P		Seeded From UniProt	complete
involved_in	GO:0060978	angiogenesis involved in coronary vascular morphogenesis	PMID:24401374^[8]	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P97333	P		Seeded From UniProt	complete
involved_in	GO:0060385	axonogenesis involved in innervation	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P97333	P	occurs_in:(UBERON:0000948)\|occurs_in:(UBERON:0000947)	Seeded From UniProt	complete
involved_in	GO:0050918	positive chemotaxis	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P97333	P	occurs_in:(CL:0000740)	Seeded From UniProt	complete
involved_in	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	PMID:21245381^[9]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0048846	axon extension involved in axon guidance	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P97333	P		Seeded From UniProt	complete
involved_in	GO:0048844	artery morphogenesis	PMID:24401374^[8]	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P97333	P	occurs_in:(UBERON:0000948)	Seeded From UniProt	complete
involved_in	GO:0048844	artery morphogenesis	PMID:23639442^[6]	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P97333	P		Seeded From UniProt	complete
involved_in	GO:0048842	positive regulation of axon extension involved in axon guidance	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P97333	P	occurs_in:(CL:0000740) occurs_in:(UBERON:0000959)	Seeded From UniProt	complete
involved_in	GO:0048012	hepatocyte growth factor receptor signaling pathway	PMID:21245381^[9]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0048010	vascular endothelial growth factor receptor signaling pathway	PMID:21245381^[9]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0048008	platelet-derived growth factor receptor signaling pathway	PMID:21245381^[9]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0038190	VEGF-activated neuropilin signaling pathway	PMID:23639442^[6]	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P97333	P		Seeded From UniProt	complete
enables	GO:0038085	vascular endothelial growth factor binding	PMID:24401374^[8]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:P15692-4	F		Seeded From UniProt	complete
involved_in	GO:0035924	cellular response to vascular endothelial growth factor stimulus	PMID:24401374^[8]	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P97333	P		Seeded From UniProt	complete
involved_in	GO:0035767	endothelial cell chemotaxis	PMID:21245381^[9]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	part_of:(GO:0035924) occurs_in:(CL:0002618)\|part_of(GO:0035729)\|part_of(GO:0036120)	Seeded From UniProt	complete
involved_in	GO:0035729	cellular response to hepatocyte growth factor stimulus	PMID:21245381^[9]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0031290	retinal ganglion cell axon guidance	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P97333	P		Seeded From UniProt	complete
part_of	GO:0030424	axon	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P97333	C	part_of:(CL:0000740) part_of:(UBERON:0000959)	Seeded From UniProt	complete
involved_in	GO:0021675	nerve development	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P97333	P		Seeded From UniProt	complete
enables	GO:0019955	cytokine binding	PMID:19909241^[7]	ECO:0000303	author statement without traceable support used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0017154	semaphorin receptor activity	PMID:19909241^[7]	ECO:0000303	author statement without traceable support used in manual assertion		F		Seeded From UniProt	complete
involved_in	GO:0007411	axon guidance	PMID:19909241^[7]	ECO:0000303	author statement without traceable support used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	PMID:21245381^[9]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005829	cytosol	PMID:21245381^[9]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005769	early endosome	PMID:23639442^[6]	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P97333	C		Seeded From UniProt	complete
enables	GO:0005021	vascular endothelial growth factor-activated receptor activity	PMID:19909241^[7]	ECO:0000303	author statement without traceable support used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0005021	vascular endothelial growth factor-activated receptor activity	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P97333	F	occurs_in:(CL:0000740)	Seeded From UniProt	complete
part_of	GO:0002116	semaphorin receptor complex	PMID:19909241^[7]	ECO:0000303	author statement without traceable support used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0002042	cell migration involved in sprouting angiogenesis	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P97333	P	happens_during:(GO:0030902) occurs_in:(CL:0000115)	Seeded From UniProt	complete
involved_in	GO:0002040	sprouting angiogenesis	PMID:24401374^[8]	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P97333	P		Seeded From UniProt	complete
involved_in	GO:0001764	neuron migration	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P97333	P		Seeded From UniProt	complete
involved_in	GO:0001569	branching involved in blood vessel morphogenesis	PMID:24401374^[8]	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P97333	P	occurs_in:(UBERON:0002028)\|occurs_in:(UBERON:0000966)	Seeded From UniProt	complete
involved_in	GO:0001569	branching involved in blood vessel morphogenesis	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P97333	P	happens_during:(GO:0030902) part_of:(CL:0000115)	Seeded From UniProt	complete
involved_in	GO:0001525	angiogenesis	PMID:23639442^[6]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	occurs_in:(CL:0002618)	Seeded From UniProt	complete
involved_in	GO:0001525	angiogenesis	PMID:24401374^[8]	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P97333	P	occurs_in:(UBERON:0000966)	Seeded From UniProt	complete
involved_in	GO:0042327	positive regulation of phosphorylation	PMID:24863063^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	part_of:(GO:0007229) part_of:(GO:0038189) occurs_in:(CL:0000115) has_regulation_target:(UniProtKB:P49023) positively_regulates:(GO:0043542)	Seeded From UniProt	complete
involved_in	GO:1900026	positive regulation of substrate adhesion-dependent cell spreading	PMID:24863063^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	part_of:(GO:0007229) part_of:(GO:0038189)	Seeded From UniProt	complete
involved_in	GO:0010595	positive regulation of endothelial cell migration	PMID:24863063^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	part_of:(GO:0007229) part_of:(GO:0038189)	Seeded From UniProt	complete
involved_in	GO:0038190	VEGF-activated neuropilin signaling pathway	PMID:24863063^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	causally_upstream_of:(GO:0043491)	Seeded From UniProt	complete
involved_in	GO:0042327	positive regulation of phosphorylation	PMID:24863063^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	has_regulation_target:(UniProtKB:P35968) part_of:(GO:0038190)	Seeded From UniProt	complete
involved_in	GO:0007229	integrin-mediated signaling pathway	PMID:26051942^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0005096	GTPase activator activity	PMID:26051942^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		F	has_input:(UniProtKB:P60953) part_of:(GO:0038189) part_of:(GO:0007229) part_of:(GO:0090050)	Seeded From UniProt	complete
enables	GO:0019838	growth factor binding	PMID:9529250^[10]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:P15692-4	F		Seeded From UniProt	complete
involved_in	GO:0043547	positive regulation of GTPase activity	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0005096	P		Seeded From UniProt	complete
involved_in	GO:2001237	negative regulation of extrinsic apoptotic signaling pathway	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P97333 ensembl:ENSMUSP00000026917	P		Seeded From UniProt	complete
involved_in	GO:1905040	otic placode development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P97333 ensembl:ENSMUSP00000026917	P		Seeded From UniProt	complete
involved_in	GO:1904835	dorsal root ganglion morphogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P97333 ensembl:ENSMUSP00000026917	P		Seeded From UniProt	complete
involved_in	GO:1903375	facioacoustic ganglion development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P97333 ensembl:ENSMUSP00000026917	P		Seeded From UniProt	complete
involved_in	GO:1902946	protein localization to early endosome	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P97333 ensembl:ENSMUSP00000026917	P		Seeded From UniProt	complete
involved_in	GO:1902378	VEGF-activated neuropilin signaling pathway involved in axon guidance	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P97333 ensembl:ENSMUSP00000026917	P		Seeded From UniProt	complete
involved_in	GO:1902336	positive regulation of retinal ganglion cell axon guidance	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P97333 ensembl:ENSMUSP00000026917	P		Seeded From UniProt	complete
involved_in	GO:1902287	semaphorin-plexin signaling pathway involved in axon guidance	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P97333 ensembl:ENSMUSP00000026917	P		Seeded From UniProt	complete
involved_in	GO:1902285	semaphorin-plexin signaling pathway involved in neuron projection guidance	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P97333 ensembl:ENSMUSP00000026917	P		Seeded From UniProt	complete
involved_in	GO:1901998	toxin transport	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P97333 ensembl:ENSMUSP00000026917	P		Seeded From UniProt	complete
involved_in	GO:1901166	neural crest cell migration involved in autonomic nervous system development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P97333 ensembl:ENSMUSP00000026917	P		Seeded From UniProt	complete
involved_in	GO:0150020	basal dendrite arborization	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P97333 ensembl:ENSMUSP00000026917	P		Seeded From UniProt	complete
involved_in	GO:0150018	basal dendrite development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P97333 ensembl:ENSMUSP00000026917	P		Seeded From UniProt	complete
involved_in	GO:0099173	postsynapse organization	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P97333 ensembl:ENSMUSP00000026917	P		Seeded From UniProt	complete
part_of	GO:0099055	integral component of postsynaptic membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P97333 ensembl:ENSMUSP00000026917	C		Seeded From UniProt	complete
part_of	GO:0098978	glutamatergic synapse	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P97333 ensembl:ENSMUSP00000026917	C		Seeded From UniProt	complete
involved_in	GO:0097491	sympathetic neuron projection guidance	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P97333 ensembl:ENSMUSP00000026917	P		Seeded From UniProt	complete
involved_in	GO:0097490	sympathetic neuron projection extension	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P97333 ensembl:ENSMUSP00000026917	P		Seeded From UniProt	complete
involved_in	GO:0097475	motor neuron migration	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P97333 ensembl:ENSMUSP00000026917	P		Seeded From UniProt	complete
part_of	GO:0097443	sorting endosome	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P97333 ensembl:ENSMUSP00000026917	C		Seeded From UniProt	complete
involved_in	GO:0097374	sensory neuron axon guidance	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P97333 ensembl:ENSMUSP00000026917	P		Seeded From UniProt	complete
involved_in	GO:0090259	regulation of retinal ganglion cell axon guidance	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P97333 ensembl:ENSMUSP00000026917	P		Seeded From UniProt	complete
involved_in	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P97333 ensembl:ENSMUSP00000026917	P		Seeded From UniProt	complete
involved_in	GO:0071679	commissural neuron axon guidance	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P97333 ensembl:ENSMUSP00000026917	P		Seeded From UniProt	complete
involved_in	GO:0071526	semaphorin-plexin signaling pathway	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P97333 ensembl:ENSMUSP00000026917	P		Seeded From UniProt	complete
involved_in	GO:0070374	positive regulation of ERK1 and ERK2 cascade	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P97333 ensembl:ENSMUSP00000026917	P		Seeded From UniProt	complete
involved_in	GO:0061551	trigeminal ganglion development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P97333 ensembl:ENSMUSP00000026917	P		Seeded From UniProt	complete
involved_in	GO:0061549	sympathetic ganglion development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P97333 ensembl:ENSMUSP00000026917	P		Seeded From UniProt	complete
involved_in	GO:0061441	renal artery morphogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P97333 ensembl:ENSMUSP00000026917	P		Seeded From UniProt	complete
involved_in	GO:0061299	retina vasculature morphogenesis in camera-type eye	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P97333 ensembl:ENSMUSP00000026917	P		Seeded From UniProt	complete
involved_in	GO:0060982	coronary artery morphogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P97333 ensembl:ENSMUSP00000026917	P		Seeded From UniProt	complete
involved_in	GO:0060978	angiogenesis involved in coronary vascular morphogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P97333 ensembl:ENSMUSP00000026917	P		Seeded From UniProt	complete
involved_in	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P97333 ensembl:ENSMUSP00000026917	P		Seeded From UniProt	complete
involved_in	GO:0060385	axonogenesis involved in innervation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P97333 ensembl:ENSMUSP00000026917	P		Seeded From UniProt	complete
involved_in	GO:0051491	positive regulation of filopodium assembly	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P97333 ensembl:ENSMUSP00000026917	P		Seeded From UniProt	complete
involved_in	GO:0050918	positive chemotaxis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P97333 ensembl:ENSMUSP00000026917	P		Seeded From UniProt	complete
involved_in	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P97333 ensembl:ENSMUSP00000026917	P		Seeded From UniProt	complete
involved_in	GO:0048846	axon extension involved in axon guidance	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P97333 ensembl:ENSMUSP00000026917	P		Seeded From UniProt	complete
involved_in	GO:0048844	artery morphogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P97333 ensembl:ENSMUSP00000026917	P		Seeded From UniProt	complete
involved_in	GO:0048843	negative regulation of axon extension involved in axon guidance	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P97333 ensembl:ENSMUSP00000026917	P		Seeded From UniProt	complete
involved_in	GO:0048842	positive regulation of axon extension involved in axon guidance	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P97333 ensembl:ENSMUSP00000026917	P		Seeded From UniProt	complete
involved_in	GO:0048841	regulation of axon extension involved in axon guidance	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P97333 ensembl:ENSMUSP00000026917	P		Seeded From UniProt	complete
involved_in	GO:0048666	neuron development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P97333 ensembl:ENSMUSP00000026917	P		Seeded From UniProt	complete
involved_in	GO:0048485	sympathetic nervous system development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P97333 ensembl:ENSMUSP00000026917	P		Seeded From UniProt	complete
involved_in	GO:0048010	vascular endothelial growth factor receptor signaling pathway	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P97333 ensembl:ENSMUSP00000026917	P		Seeded From UniProt	complete
involved_in	GO:0045766	positive regulation of angiogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P97333 ensembl:ENSMUSP00000026917	P		Seeded From UniProt	complete
involved_in	GO:0043542	endothelial cell migration	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P97333 ensembl:ENSMUSP00000026917	P		Seeded From UniProt	complete
involved_in	GO:0043524	negative regulation of neuron apoptotic process	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P97333 ensembl:ENSMUSP00000026917	P		Seeded From UniProt	complete
part_of	GO:0043005	neuron projection	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P97333 ensembl:ENSMUSP00000026917	C		Seeded From UniProt	complete
involved_in	GO:0042327	positive regulation of phosphorylation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P97333 ensembl:ENSMUSP00000026917	P		Seeded From UniProt	complete
involved_in	GO:0038190	VEGF-activated neuropilin signaling pathway	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P97333 ensembl:ENSMUSP00000026917	P		Seeded From UniProt	complete
involved_in	GO:0038189	neuropilin signaling pathway	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P97333 ensembl:ENSMUSP00000026917	P		Seeded From UniProt	complete
enables	GO:0038085	vascular endothelial growth factor binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P97333 ensembl:ENSMUSP00000026917	F		Seeded From UniProt	complete
involved_in	GO:0036486	ventral trunk neural crest cell migration	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P97333 ensembl:ENSMUSP00000026917	P		Seeded From UniProt	complete
involved_in	GO:0035924	cellular response to vascular endothelial growth factor stimulus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P97333 ensembl:ENSMUSP00000026917	P		Seeded From UniProt	complete
involved_in	GO:0032489	regulation of Cdc42 protein signal transduction	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P97333 ensembl:ENSMUSP00000026917	P		Seeded From UniProt	complete
involved_in	GO:0031290	retinal ganglion cell axon guidance	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P97333 ensembl:ENSMUSP00000026917	P		Seeded From UniProt	complete
involved_in	GO:0030517	negative regulation of axon extension	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P97333 ensembl:ENSMUSP00000026917	P		Seeded From UniProt	complete
part_of	GO:0030424	axon	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P97333 ensembl:ENSMUSP00000026917	C		Seeded From UniProt	complete
involved_in	GO:0021828	gonadotrophin-releasing hormone neuronal migration to the hypothalamus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P97333 ensembl:ENSMUSP00000026917	P		Seeded From UniProt	complete
involved_in	GO:0021785	branchiomotor neuron axon guidance	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P97333 ensembl:ENSMUSP00000026917	P		Seeded From UniProt	complete
involved_in	GO:0021675	nerve development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P97333 ensembl:ENSMUSP00000026917	P		Seeded From UniProt	complete
involved_in	GO:0021649	vestibulocochlear nerve structural organization	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P97333 ensembl:ENSMUSP00000026917	P		Seeded From UniProt	complete
involved_in	GO:0021637	trigeminal nerve structural organization	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P97333 ensembl:ENSMUSP00000026917	P		Seeded From UniProt	complete
involved_in	GO:0021636	trigeminal nerve morphogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P97333 ensembl:ENSMUSP00000026917	P		Seeded From UniProt	complete
involved_in	GO:0021612	facial nerve structural organization	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P97333 ensembl:ENSMUSP00000026917	P		Seeded From UniProt	complete
enables	GO:0019901	protein kinase binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P97333 ensembl:ENSMUSP00000026917	F		Seeded From UniProt	complete
enables	GO:0019838	growth factor binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P97333 ensembl:ENSMUSP00000026917	F		Seeded From UniProt	complete
enables	GO:0017154	semaphorin receptor activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P97333 ensembl:ENSMUSP00000026917	F		Seeded From UniProt	complete
involved_in	GO:0016477	cell migration	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P97333 ensembl:ENSMUSP00000026917	P		Seeded From UniProt	complete
involved_in	GO:0016358	dendrite development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P97333 ensembl:ENSMUSP00000026917	P		Seeded From UniProt	complete
involved_in	GO:0010595	positive regulation of endothelial cell migration	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P97333 ensembl:ENSMUSP00000026917	P		Seeded From UniProt	complete
involved_in	GO:0008045	motor neuron axon guidance	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P97333 ensembl:ENSMUSP00000026917	P		Seeded From UniProt	complete
involved_in	GO:0007507	heart development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P97333 ensembl:ENSMUSP00000026917	P		Seeded From UniProt	complete
involved_in	GO:0007413	axonal fasciculation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P97333 ensembl:ENSMUSP00000026917	P		Seeded From UniProt	complete
involved_in	GO:0007411	axon guidance	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P97333 ensembl:ENSMUSP00000026917	P		Seeded From UniProt	complete
involved_in	GO:0007229	integrin-mediated signaling pathway	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P97333 ensembl:ENSMUSP00000026917	P		Seeded From UniProt	complete
part_of	GO:0005925	focal adhesion	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P97333 ensembl:ENSMUSP00000026917	C		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P97333 ensembl:ENSMUSP00000026917	C		Seeded From UniProt	complete
part_of	GO:0005883	neurofilament	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P97333 ensembl:ENSMUSP00000026917	C		Seeded From UniProt	complete
part_of	GO:0005769	early endosome	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P97333 ensembl:ENSMUSP00000026917	C		Seeded From UniProt	complete
enables	GO:0005021	vascular endothelial growth factor-activated receptor activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P97333 ensembl:ENSMUSP00000026917	F		Seeded From UniProt	complete
involved_in	GO:0003148	outflow tract septum morphogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P97333 ensembl:ENSMUSP00000026917	P		Seeded From UniProt	complete
involved_in	GO:0002042	cell migration involved in sprouting angiogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P97333 ensembl:ENSMUSP00000026917	P		Seeded From UniProt	complete
involved_in	GO:0002040	sprouting angiogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P97333 ensembl:ENSMUSP00000026917	P		Seeded From UniProt	complete
involved_in	GO:0001764	neuron migration	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P97333 ensembl:ENSMUSP00000026917	P		Seeded From UniProt	complete
involved_in	GO:0001569	branching involved in blood vessel morphogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P97333 ensembl:ENSMUSP00000026917	P		Seeded From UniProt	complete
involved_in	GO:0001525	angiogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P97333 ensembl:ENSMUSP00000026917	P		Seeded From UniProt	complete
involved_in	GO:0048843	negative regulation of axon extension involved in axon guidance	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9QWJ9 ensembl:ENSRNOP00000075034	P		Seeded From UniProt	complete
part_of	GO:0043025	neuronal cell body	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9QWJ9 ensembl:ENSRNOP00000075034	C		Seeded From UniProt	complete
part_of	GO:0030426	growth cone	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9QWJ9 ensembl:ENSRNOP00000075034	C		Seeded From UniProt	complete
part_of	GO:0030424	axon	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9QWJ9 ensembl:ENSRNOP00000075034	C		Seeded From UniProt	complete
enables	GO:0017154	semaphorin receptor activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9QWJ9 ensembl:ENSRNOP00000075034	F		Seeded From UniProt	complete
part_of	GO:0009986	cell surface	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9QWJ9 ensembl:ENSRNOP00000075034	C		Seeded From UniProt	complete
involved_in	GO:0009611	response to wounding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9QWJ9 ensembl:ENSRNOP00000075034	P		Seeded From UniProt	complete
involved_in	GO:0001525	angiogenesis	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR014648 InterPro:IPR027146	P		Seeded From UniProt	complete
enables	GO:0005021	vascular endothelial growth factor-activated receptor activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR014648 InterPro:IPR027146	F		Seeded From UniProt	complete
involved_in	GO:0007411	axon guidance	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR014648 InterPro:IPR027146	P		Seeded From UniProt	complete
involved_in	GO:0009887	animal organ morphogenesis	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR027146	P		Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000998	C		Seeded From UniProt	complete
enables	GO:0017154	semaphorin receptor activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR014648 InterPro:IPR027146	F		Seeded From UniProt	complete
enables	GO:0019838	growth factor binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR027146	F		Seeded From UniProt	complete
involved_in	GO:0035767	endothelial cell chemotaxis	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR027146	P		Seeded From UniProt	complete
involved_in	GO:0038084	vascular endothelial growth factor signaling pathway	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR014648	P		Seeded From UniProt	complete
involved_in	GO:0048010	vascular endothelial growth factor receptor signaling pathway	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR027146	P		Seeded From UniProt	complete
involved_in	GO:0071526	semaphorin-plexin signaling pathway	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR027146	P		Seeded From UniProt	complete
involved_in	GO:0009887	animal organ morphogenesis	PMID:9529250^[10]	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0007411	axon guidance	PMID:9288753^[11]	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0007267	cell-cell signaling	PMID:9288753^[11]	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0007165	signal transduction	PMID:9288753^[11]	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0005021	vascular endothelial growth factor-activated receptor activity	PMID:9288753^[11]	ECO:0000304	author statement supported by traceable reference used in manual assertion		F		Seeded From UniProt	complete
involved_in	GO:0060627	regulation of vesicle-mediated transport	PMID:21245381^[9]	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0060301	positive regulation of cytokine activity	PMID:21245381^[9]	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0043235	receptor complex	PMID:21245381^[9]	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0031410	cytoplasmic vesicle	PMID:21245381^[9]	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
enables	GO:0019838	growth factor binding	PMID:21245381^[9]	ECO:0000304	author statement supported by traceable reference used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0015026	coreceptor activity	PMID:21245381^[9]	ECO:0000304	author statement supported by traceable reference used in manual assertion		F		Seeded From UniProt	complete
involved_in	GO:0014911	positive regulation of smooth muscle cell migration	PMID:21245381^[9]	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0010595	positive regulation of endothelial cell migration	PMID:21245381^[9]	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0001938	positive regulation of endothelial cell proliferation	PMID:21245381^[9]	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0048010	vascular endothelial growth factor receptor signaling pathway	Reactome:R-HSA-194138	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	Reactome:R-HSA-399952 Reactome:R-HSA-399951 Reactome:R-HSA-399947 Reactome:R-HSA-399944 Reactome:R-HSA-399939 Reactome:R-HSA-399933 Reactome:R-HSA-399930 Reactome:R-HSA-374669 Reactome:R-HSA-195408	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0007275	multicellular organism development	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0217	P		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-1003 UniProtKB-SubCell:SL-0039	C		Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0812	C		Seeded From UniProt	complete
involved_in	GO:0030154	cell differentiation	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0221	P		Seeded From UniProt	complete
involved_in	GO:0001525	angiogenesis	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0037	P		Seeded From UniProt	complete
enables	GO:0046872	metal ion binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0479	F		Seeded From UniProt	complete
part_of	GO:0005576	extracellular region	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0964 UniProtKB-SubCell:SL-0243	C		Seeded From UniProt	complete
involved_in	GO:0007399	nervous system development	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0524	P		Seeded From UniProt	complete
enables	GO:0008201	heparin binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0358	F		Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0472	C		Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 ^1.2 de Anda, FC et al. (2012) Autism spectrum disorder susceptibility gene TAOK2 affects basal dendrite formation in the neocortex. Nat. Neurosci. 15 1022-31 PubMed GONUTS page
↑ ^2.00 ^2.01 ^2.02 ^2.03 ^2.04 ^2.05 ^2.06 ^2.07 ^2.08 ^2.09 ^2.10 ^2.11 ^2.12 ^2.13 ^2.14 ^2.15 ^2.16 Raimondi, C et al. (2014) Imatinib inhibits VEGF-independent angiogenesis by targeting neuropilin 1-dependent ABL1 activation in endothelial cells. J. Exp. Med. 211 1167-83 PubMed GONUTS page
↑ ^3.0 ^3.1 ^3.2 ^3.3 ^3.4 ^3.5 ^3.6 Fantin, A et al. (2015) NRP1 Regulates CDC42 Activation to Promote Filopodia Formation in Endothelial Tip Cells. Cell Rep 11 1577-90 PubMed GONUTS page
↑ Kuo, JC et al. (2011) Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation. Nat. Cell Biol. 13 383-93 PubMed GONUTS page
↑ Palmer, DJ et al. (2006) Human colostrum: identification of minor proteins in the aqueous phase by proteomics. Proteomics 6 2208-16 PubMed GONUTS page
↑ ^6.0 ^6.1 ^6.2 ^6.3 ^6.4 ^6.5 ^6.6 Lanahan, A et al. (2013) The neuropilin 1 cytoplasmic domain is required for VEGF-A-dependent arteriogenesis. Dev. Cell 25 156-68 PubMed GONUTS page
↑ ^7.0 ^7.1 ^7.2 ^7.3 ^7.4 ^7.5 Zachary, IC et al. (2009) The role of neuropilins in cell signalling. Biochem. Soc. Trans. 37 1171-8 PubMed GONUTS page
↑ ^8.0 ^8.1 ^8.2 ^8.3 ^8.4 ^8.5 ^8.6 ^8.7 Fantin, A et al. (2014) Neuropilin 1 (NRP1) hypomorphism combined with defective VEGF-A binding reveals novel roles for NRP1 in developmental and pathological angiogenesis. Development 141 556-62 PubMed GONUTS page
↑ ^9.00 ^9.01 ^9.02 ^9.03 ^9.04 ^9.05 ^9.06 ^9.07 ^9.08 ^9.09 ^9.10 ^9.11 ^9.12 ^9.13 ^9.14 ^9.15 ^9.16 Evans, IM et al. (2011) Neuropilin-1 signaling through p130Cas tyrosine phosphorylation is essential for growth factor-dependent migration of glioma and endothelial cells. Mol. Cell. Biol. 31 1174-85 PubMed GONUTS page
↑ ^10.0 ^10.1 Soker, S et al. (1998) Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor. Cell 92 735-45 PubMed GONUTS page
↑ ^11.0 ^11.1 ^11.2 ^11.3 He, Z & Tessier-Lavigne, M (1997) Neuropilin is a receptor for the axonal chemorepellent Semaphorin III. Cell 90 739-51 PubMed GONUTS page

[PMID:22683681-1] 1.0 ^1.1 ^1.2 de Anda, FC et al. (2012) Autism spectrum disorder susceptibility gene TAOK2 affects basal dendrite formation in the neocortex. Nat. Neurosci. 15 1022-31 PubMed GONUTS page

[PMID:24863063-2] 2.00 ^2.01 ^2.02 ^2.03 ^2.04 ^2.05 ^2.06 ^2.07 ^2.08 ^2.09 ^2.10 ^2.11 ^2.12 ^2.13 ^2.14 ^2.15 ^2.16 Raimondi, C et al. (2014) Imatinib inhibits VEGF-independent angiogenesis by targeting neuropilin 1-dependent ABL1 activation in endothelial cells. J. Exp. Med. 211 1167-83 PubMed GONUTS page

[PMID:26051942-3] 3.0 ^3.1 ^3.2 ^3.3 ^3.4 ^3.5 ^3.6 Fantin, A et al. (2015) NRP1 Regulates CDC42 Activation to Promote Filopodia Formation in Endothelial Tip Cells. Cell Rep 11 1577-90 PubMed GONUTS page

[PMID:21423176-4] Kuo, JC et al. (2011) Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation. Nat. Cell Biol. 13 383-93 PubMed GONUTS page

[PMID:16502470-5] Palmer, DJ et al. (2006) Human colostrum: identification of minor proteins in the aqueous phase by proteomics. Proteomics 6 2208-16 PubMed GONUTS page

[PMID:23639442-6] 6.0 ^6.1 ^6.2 ^6.3 ^6.4 ^6.5 ^6.6 Lanahan, A et al. (2013) The neuropilin 1 cytoplasmic domain is required for VEGF-A-dependent arteriogenesis. Dev. Cell 25 156-68 PubMed GONUTS page

[PMID:19909241-7] 7.0 ^7.1 ^7.2 ^7.3 ^7.4 ^7.5 Zachary, IC et al. (2009) The role of neuropilins in cell signalling. Biochem. Soc. Trans. 37 1171-8 PubMed GONUTS page

[PMID:24401374-8] 8.0 ^8.1 ^8.2 ^8.3 ^8.4 ^8.5 ^8.6 ^8.7 Fantin, A et al. (2014) Neuropilin 1 (NRP1) hypomorphism combined with defective VEGF-A binding reveals novel roles for NRP1 in developmental and pathological angiogenesis. Development 141 556-62 PubMed GONUTS page

[PMID:21245381-9] 9.00 ^9.01 ^9.02 ^9.03 ^9.04 ^9.05 ^9.06 ^9.07 ^9.08 ^9.09 ^9.10 ^9.11 ^9.12 ^9.13 ^9.14 ^9.15 ^9.16 Evans, IM et al. (2011) Neuropilin-1 signaling through p130Cas tyrosine phosphorylation is essential for growth factor-dependent migration of glioma and endothelial cells. Mol. Cell. Biol. 31 1174-85 PubMed GONUTS page

[PMID:9529250-10] 10.0 ^10.1 Soker, S et al. (1998) Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor. Cell 92 735-45 PubMed GONUTS page

[PMID:9288753-11] 11.0 ^11.1 ^11.2 ^11.3 He, Z & Tessier-Lavigne, M (1997) Neuropilin is a receptor for the axonal chemorepellent Semaphorin III. Cell 90 739-51 PubMed GONUTS page

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