MOUSE:VEGFC

Species (Taxon ID)	Mus musculus (Mouse). (10090)
Gene Name(s)	Vegfc
Protein Name(s)	Vascular endothelial growth factor C VEGF-C Flt4 ligand Flt4-L Vascular endothelial growth factor-related protein VRP
External Links
UniProt	P97953
EMBL	U73620 U58112 EU862553 EU862554 EU862555 AK047844 CH466554 BC096377
CCDS	CCDS22306.1
RefSeq	NP_033532.1
UniGene	Mm.1402
ProteinModelPortal	P97953
SMR	P97953
BioGrid	204514
DIP	DIP-61403N
STRING	10090.ENSMUSP00000033919
PhosphoSite	P97953
PaxDb	P97953
PRIDE	P97953
Ensembl	ENSMUST00000033919
GeneID	22341
KEGG	mmu:22341
UCSC	uc009lsc.1 uc029wsy.1
CTD	7424
MGI	MGI:109124
eggNOG	ENOG410IFTP ENOG410YGVZ
GeneTree	ENSGT00730000110889
HOGENOM	HOG000231512
HOVERGEN	HBG073119
InParanoid	P97953
KO	K05449
OMA	TCPRNQP
OrthoDB	EOG7J17ZS
PhylomeDB	P97953
TreeFam	TF319554
Reactome	R-MMU-114608 R-MMU-194313 R-MMU-195399
NextBio	302605
PRO	PR:P97953
Proteomes	UP000000589
Bgee	P97953
CleanEx	MM_VEGFC
Genevisible	P97953
GO	GO:0005615 GO:0016020 GO:0042056 GO:0043185 GO:0001525 GO:0050930 GO:0016331 GO:0045776 GO:0008285 GO:0009887 GO:0050918 GO:0045766 GO:0043536 GO:0051781 GO:0008284 GO:0001954 GO:0050679 GO:1901492 GO:0060754 GO:0002052 GO:0050731 GO:0031954 GO:0050714 GO:0030947 GO:0042493 GO:0048010
Gene3D	2.10.90.10
InterPro	IPR004153 IPR029034 IPR023581 IPR000072
Pfam	PF03128 PF00341
SMART	SM00141
SUPFAM	SSF57501
PROSITE	PS00249 PS50278

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:1902462	positive regulation of mesenchymal stem cell proliferation	PMID:26934950^[1]	ECO:0000314			P		Figure 2A shows increased proliferation of the MSC SG-2 cell line.	complete CACAO 11550
	GO:0030335	positive regulation of cell migration	PMID:26934950^[1]	ECO:0000314			P		Figure 2B shows increased cell migration especially in the MSC SG-2 line.	complete CACAO 11551
	GO:0045860	positive regulation of protein kinase activity	PMID:26934950^[1]	ECO:0000314			P		Figure 3 shows increased ERK1/2 phosphorylation.	complete CACAO 11552
	GO:0060836	lymphatic endothelial cell differentiation	PMID:26934950^[1]	ECO:0000314			P		Figure 4 A and B shows increased levels of expression of genes specific to lymphatic endothelial cell, Prox1 and Lyve1.	complete CACAO 11553
	GO:0045668	negative regulation of osteoblast differentiation	PMID:26934950^[1]	ECO:0000314			P		Figure 4 C-F shows reduced expression of late-stage osteogenic differentiation marker genes.	complete CACAO 11554
part_of	GO:0005615	extracellular space	PMID:24006456^[2]	ECO:0007005	high throughput direct assay evidence used in manual assertion		C	produced_by:(CL:0002548)	Seeded From UniProt	complete
involved_in	GO:1901492	positive regulation of lymphangiogenesis	PMID:24552833^[3]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0048010	vascular endothelial growth factor receptor signaling pathway	PMID:24552833^[3]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0045766	positive regulation of angiogenesis	PMID:24552833^[3]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005615	extracellular space	PMID:24552833^[3]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0060754	positive regulation of mast cell chemotaxis	PMID:21873635^[4]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000246442 UniProtKB:O43915 UniProtKB:P15692 UniProtKB:P49765 UniProtKB:P49767	P		Seeded From UniProt	complete
involved_in	GO:0050930	induction of positive chemotaxis	PMID:21873635^[4]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000246442 UniProtKB:O43915 UniProtKB:P15692 UniProtKB:P49765 UniProtKB:P49767	P		Seeded From UniProt	complete
involved_in	GO:0048010	vascular endothelial growth factor receptor signaling pathway	PMID:21873635^[4]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:103178 MGI:MGI:108037 MGI:MGI:109124 PANTHER:PTN000246442 RGD:619991 RGD:620695 UniProtKB:P15692 UniProtKB:P49767 ZFIN:ZDB-GENE-990415-273	P		Seeded From UniProt	complete
involved_in	GO:0045766	positive regulation of angiogenesis	PMID:21873635^[4]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:103178 MGI:MGI:109124 PANTHER:PTN000246442 RGD:619850 RGD:619991 UniProtKB:P15692	P		Seeded From UniProt	complete
enables	GO:0043185	vascular endothelial growth factor receptor 3 binding	PMID:21873635^[4]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:109124 PANTHER:PTN002635033 RGD:619800 UniProtKB:P49767	F		Seeded From UniProt	complete
enables	GO:0042056	chemoattractant activity	PMID:21873635^[4]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:103178 PANTHER:PTN000246442 RGD:619991 UniProtKB:O43915 UniProtKB:P15692 UniProtKB:P49765 UniProtKB:P49767	F		Seeded From UniProt	complete
involved_in	GO:0038084	vascular endothelial growth factor signaling pathway	PMID:21873635^[4]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:103178 PANTHER:PTN000246442 UniProtKB:P15692 ZFIN:ZDB-GENE-040303-4	P		Seeded From UniProt	complete
enables	GO:0008083	growth factor activity	PMID:21873635^[4]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:103178 MGI:MGI:108037 PANTHER:PTN000246442 RGD:619991 UniProtKB:P15691 UniProtKB:P15692 UniProtKB:P49763	F		Seeded From UniProt	complete
part_of	GO:0005615	extracellular space	PMID:21873635^[4]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:103178 MGI:MGI:105095 MGI:MGI:108037 MGI:MGI:109124 PANTHER:PTN000246442 RGD:619850 RGD:619991 UniProtKB:P15691 UniProtKB:P15692 UniProtKB:P49765	C		Seeded From UniProt	complete
enables	GO:0005172	vascular endothelial growth factor receptor binding	PMID:21873635^[4]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:103178 MGI:MGI:108037 MGI:MGI:109124 PANTHER:PTN000246442 RGD:619800 RGD:619991 RGD:620695 UniProtKB:O43915 UniProtKB:P15692 UniProtKB:P49765 UniProtKB:P49767 ZFIN:ZDB-GENE-040303-4	F		Seeded From UniProt	complete
involved_in	GO:0002040	sprouting angiogenesis	PMID:21873635^[4]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:103178 PANTHER:PTN000246442 RGD:619850 ZFIN:ZDB-GENE-030131-4605 ZFIN:ZDB-GENE-040303-4	P		Seeded From UniProt	complete
involved_in	GO:0001938	positive regulation of endothelial cell proliferation	PMID:21873635^[4]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:103178 PANTHER:PTN000246442 RGD:619850 UniProtKB:P15691 UniProtKB:P15692 UniProtKB:P49765	P		Seeded From UniProt	complete
involved_in	GO:0001934	positive regulation of protein phosphorylation	PMID:21873635^[4]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000246442 UniProtKB:P15692	P		Seeded From UniProt	complete
involved_in	GO:0001666	response to hypoxia	PMID:21873635^[4]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000246442 RGD:619850 RGD:619991 RGD:620695 UniProtKB:P15692	P		Seeded From UniProt	complete
involved_in	GO:0001525	angiogenesis	PMID:21873635^[4]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:103178 PANTHER:PTN000246442 RGD:619799 RGD:619800 RGD:619991 UniProtKB:P15692 ZFIN:ZDB-GENE-070810-6	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:1990830	cellular response to leukemia inhibitory factor	PMID:20439489^[5]	ECO:0000270	expression pattern evidence used in manual assertion		P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:1901492	positive regulation of lymphangiogenesis	PMID:20133819^[6]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0060754	positive regulation of mast cell chemotaxis	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P49767	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0050930	induction of positive chemotaxis	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P49767	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0050714	positive regulation of protein secretion	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:619800	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0050679	positive regulation of epithelial cell proliferation	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:619800	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0048010	vascular endothelial growth factor receptor signaling pathway	PMID:9247316^[7]	ECO:0000316	genetic interaction evidence used in manual assertion	MGI:MGI:95561	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0048010	vascular endothelial growth factor receptor signaling pathway	PMID:9012504^[8]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0048010	vascular endothelial growth factor receptor signaling pathway	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P49767	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0045776	negative regulation of blood pressure	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:619800	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0043536	positive regulation of blood vessel endothelial cell migration	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:619800	P		Seeded From UniProt	complete
enables	GO:0043185	vascular endothelial growth factor receptor 3 binding	PMID:9247316^[7]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:P35917	F		Seeded From UniProt	complete
enables	GO:0043185	vascular endothelial growth factor receptor 3 binding	PMID:9012504^[8]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:P35916	F		Seeded From UniProt	complete
enables	GO:0043185	vascular endothelial growth factor receptor 3 binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P49767	F		Seeded From UniProt	complete
enables	GO:0043185	vascular endothelial growth factor receptor 3 binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:619800	F		Seeded From UniProt	complete
enables	GO:0042056	chemoattractant activity	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P49767	F		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0031954	positive regulation of protein autophosphorylation	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:619800	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0030947	regulation of vascular endothelial growth factor receptor signaling pathway	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:619800	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0016331	morphogenesis of embryonic epithelium	PMID:14634646^[9]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:3026650	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0009887	animal organ morphogenesis	PMID:14634646^[9]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:3026650	P	has_participant:(EMAPA:18248)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0008284	positive regulation of cell population proliferation	PMID:9247316^[7]	ECO:0000316	genetic interaction evidence used in manual assertion	MGI:MGI:95561	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0008284	positive regulation of cell population proliferation	PMID:16462734^[10]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:3026650	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0008284	positive regulation of cell population proliferation	GO_REF:0000008	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:O35757	P		Seeded From UniProt	complete
part_of	GO:0005615	extracellular space	PMID:9247316^[7]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0002052	positive regulation of neuroblast proliferation	GO_REF:0000008	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:O35757	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0001525	angiogenesis	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:619800	P		Seeded From UniProt	complete
involved_in	GO:0010469	regulation of signaling receptor activity	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0008083	P		Seeded From UniProt	complete
involved_in	GO:0010469	regulation of signaling receptor activity	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0008083	P		Seeded From UniProt	complete
involved_in	GO:0010469	regulation of signaling receptor activity	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0008083	P		Seeded From UniProt	complete
involved_in	GO:0050918	positive chemotaxis	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0042056	P		Seeded From UniProt	complete
involved_in	GO:0050918	positive chemotaxis	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0042056	P		Seeded From UniProt	complete
involved_in	GO:0050918	positive chemotaxis	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0042056	P		Seeded From UniProt	complete
involved_in	GO:0050714	positive regulation of protein secretion	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O35757 ensembl:ENSRNOP00000015529	P		Seeded From UniProt	complete
involved_in	GO:0050679	positive regulation of epithelial cell proliferation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O35757 ensembl:ENSRNOP00000015529	P		Seeded From UniProt	complete
involved_in	GO:0045776	negative regulation of blood pressure	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O35757 ensembl:ENSRNOP00000015529	P		Seeded From UniProt	complete
involved_in	GO:0043536	positive regulation of blood vessel endothelial cell migration	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O35757 ensembl:ENSRNOP00000015529	P		Seeded From UniProt	complete
enables	GO:0043185	vascular endothelial growth factor receptor 3 binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O35757 ensembl:ENSRNOP00000015529	F		Seeded From UniProt	complete
involved_in	GO:0042493	response to drug	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O35757 ensembl:ENSRNOP00000015529	P		Seeded From UniProt	complete
involved_in	GO:0031954	positive regulation of protein autophosphorylation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O35757 ensembl:ENSRNOP00000015529	P		Seeded From UniProt	complete
involved_in	GO:0030947	regulation of vascular endothelial growth factor receptor signaling pathway	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O35757 ensembl:ENSRNOP00000015529	P		Seeded From UniProt	complete
involved_in	GO:0008284	positive regulation of cell population proliferation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O35757 ensembl:ENSRNOP00000015529	P		Seeded From UniProt	complete
involved_in	GO:0002052	positive regulation of neuroblast proliferation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O35757 ensembl:ENSRNOP00000015529	P		Seeded From UniProt	complete
involved_in	GO:0001525	angiogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:O35757 ensembl:ENSRNOP00000015529	P		Seeded From UniProt	complete
involved_in	GO:0060754	positive regulation of mast cell chemotaxis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P49767 ensembl:ENSP00000480043	P		Seeded From UniProt	complete
involved_in	GO:0050930	induction of positive chemotaxis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P49767 ensembl:ENSP00000480043	P		Seeded From UniProt	complete
involved_in	GO:0048010	vascular endothelial growth factor receptor signaling pathway	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P49767 ensembl:ENSP00000480043	P		Seeded From UniProt	complete
enables	GO:0043185	vascular endothelial growth factor receptor 3 binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P49767 ensembl:ENSP00000480043	F		Seeded From UniProt	complete
enables	GO:0042056	chemoattractant activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P49767 ensembl:ENSP00000480043	F		Seeded From UniProt	complete
enables	GO:0008083	growth factor activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000072	F		Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000072	C		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	PMID:20415667^[11]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0008285	negative regulation of cell population proliferation	PMID:20415667^[11]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0001954	positive regulation of cell-matrix adhesion	PMID:20415667^[11]	ECO:0000314	direct assay evidence used in manual assertion		P	regulates_o_has_participant:(CL:0000653)	Seeded From UniProt	complete
enables	GO:0008083	growth factor activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0339	F		Seeded From UniProt	complete
involved_in	GO:0030154	cell differentiation	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0221	P		Seeded From UniProt	complete
part_of	GO:0005576	extracellular region	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0964 UniProtKB-SubCell:SL-0243	C		Seeded From UniProt	complete
involved_in	GO:0051781	positive regulation of cell division	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0497	P		Seeded From UniProt	complete
involved_in	GO:0001525	angiogenesis	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0037	P		Seeded From UniProt	complete
involved_in	GO:0007275	multicellular organism development	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0217	P		Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 ^1.2 ^1.3 ^1.4 Igarashi, Y et al. (2016) VEGF-C and TGF-β reciprocally regulate mesenchymal stem cell commitment to differentiation into lymphatic endothelial or osteoblastic phenotypes. Int. J. Mol. Med. 37 1005-13 PubMed GONUTS page
↑ Abonnenc, M et al. (2013) Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c. Circ. Res. 113 1138-47 PubMed GONUTS page
↑ ^3.0 ^3.1 ^3.2 ^3.3 Jeltsch, M et al. (2014) CCBE1 enhances lymphangiogenesis via A disintegrin and metalloprotease with thrombospondin motifs-3-mediated vascular endothelial growth factor-C activation. Circulation 129 1962-71 PubMed GONUTS page
↑ ^4.00 ^4.01 ^4.02 ^4.03 ^4.04 ^4.05 ^4.06 ^4.07 ^4.08 ^4.09 ^4.10 ^4.11 ^4.12 ^4.13 ^4.14 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
↑ Tarantino, C et al. (2010) miRNA 34a, 100, and 137 modulate differentiation of mouse embryonic stem cells. FASEB J. 24 3255-63 PubMed GONUTS page
↑ Heishi, T et al. (2010) Endogenous angiogenesis inhibitor vasohibin1 exhibits broad-spectrum antilymphangiogenic activity and suppresses lymph node metastasis. Am. J. Pathol. 176 1950-8 PubMed GONUTS page
↑ ^7.0 ^7.1 ^7.2 ^7.3 Fitz, LJ et al. (1997) Characterization of murine Flt4 ligand/VEGF-C. Oncogene 15 613-8 PubMed GONUTS page
↑ ^8.0 ^8.1 Kukk, E et al. (1996) VEGF-C receptor binding and pattern of expression with VEGFR-3 suggests a role in lymphatic vascular development. Development 122 3829-37 PubMed GONUTS page
↑ ^9.0 ^9.1 Karkkainen, MJ et al. (2004) Vascular endothelial growth factor C is required for sprouting of the first lymphatic vessels from embryonic veins. Nat. Immunol. 5 74-80 PubMed GONUTS page
↑ Le Bras, B et al. (2006) VEGF-C is a trophic factor for neural progenitors in the vertebrate embryonic brain. Nat. Neurosci. 9 340-8 PubMed GONUTS page
↑ ^11.0 ^11.1 ^11.2 Wang, ZG et al. (2010) Characterization of novel VEGF (vascular endothelial growth factor)-C splicing isoforms from mouse. Biochem. J. 428 347-54 PubMed GONUTS page

[PMID:26934950-1] 1.0 ^1.1 ^1.2 ^1.3 ^1.4 Igarashi, Y et al. (2016) VEGF-C and TGF-β reciprocally regulate mesenchymal stem cell commitment to differentiation into lymphatic endothelial or osteoblastic phenotypes. Int. J. Mol. Med. 37 1005-13 PubMed GONUTS page

[PMID:24006456-2] Abonnenc, M et al. (2013) Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c. Circ. Res. 113 1138-47 PubMed GONUTS page

[PMID:24552833-3] 3.0 ^3.1 ^3.2 ^3.3 Jeltsch, M et al. (2014) CCBE1 enhances lymphangiogenesis via A disintegrin and metalloprotease with thrombospondin motifs-3-mediated vascular endothelial growth factor-C activation. Circulation 129 1962-71 PubMed GONUTS page

[PMID:21873635-4] 4.00 ^4.01 ^4.02 ^4.03 ^4.04 ^4.05 ^4.06 ^4.07 ^4.08 ^4.09 ^4.10 ^4.11 ^4.12 ^4.13 ^4.14 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:20439489-5] Tarantino, C et al. (2010) miRNA 34a, 100, and 137 modulate differentiation of mouse embryonic stem cells. FASEB J. 24 3255-63 PubMed GONUTS page

[PMID:20133819-6] Heishi, T et al. (2010) Endogenous angiogenesis inhibitor vasohibin1 exhibits broad-spectrum antilymphangiogenic activity and suppresses lymph node metastasis. Am. J. Pathol. 176 1950-8 PubMed GONUTS page

[PMID:9247316-7] 7.0 ^7.1 ^7.2 ^7.3 Fitz, LJ et al. (1997) Characterization of murine Flt4 ligand/VEGF-C. Oncogene 15 613-8 PubMed GONUTS page

[PMID:9012504-8] 8.0 ^8.1 Kukk, E et al. (1996) VEGF-C receptor binding and pattern of expression with VEGFR-3 suggests a role in lymphatic vascular development. Development 122 3829-37 PubMed GONUTS page

[PMID:14634646-9] 9.0 ^9.1 Karkkainen, MJ et al. (2004) Vascular endothelial growth factor C is required for sprouting of the first lymphatic vessels from embryonic veins. Nat. Immunol. 5 74-80 PubMed GONUTS page

[PMID:16462734-10] Le Bras, B et al. (2006) VEGF-C is a trophic factor for neural progenitors in the vertebrate embryonic brain. Nat. Neurosci. 9 340-8 PubMed GONUTS page

[PMID:20415667-11] 11.0 ^11.1 ^11.2 Wang, ZG et al. (2010) Characterization of novel VEGF (vascular endothelial growth factor)-C splicing isoforms from mouse. Biochem. J. 428 347-54 PubMed GONUTS page

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