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Category:GO:0006370 ! 7-methylguanosine mRNA capping
name: 7-methylguanosine mRNA capping
namespace: biological_process
def: "The sequence of enzymatic reactions by which the mRNA 5' cap structure, an inverted 7-methylguanosine linked via a 5'-5' triphosphate bridge (m7G(5')ppp(5')X) to the first transcribed residue, is added to a nascent transcript. Additional methylation can occur on the ribose sugars of the first and second nucleotides adjacent to the m7G nRNA cap. These methylations are often referred to as N6,2'-O-dimethyladenosine (m6,2A) and N6,2'-O-dimethylguanosine (m6,2G), respectively." [GOC:mah, PMID:9266685]
synonym: "5' end capping" BROAD []
synonym: "5' mRNA capping" EXACT []
synonym: "5'-end mRNA processing" EXACT []
synonym: "5'-end processing" BROAD []
synonym: "mRNA capping" EXACT [GOC:bf, GOC:krc, GOC:mah]
is_a: GO:0006397 ! mRNA processing
is_a: GO:0009452 ! 7-methylguanosine RNA capping
AmiGO
<GOterm>GO:0006370</GOterm>
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This category has the following 2 subcategories, out of 2 total.
