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9FLAV:Q8B489

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Species (Taxon ID) Dengue virus 2. (11060)
Gene Name(s) NS5 (ECO:0000313 with EMBL:AAN77510.1)
Protein Name(s) NS5 protein (ECO:0000313 with EMBL:AAN77510.1)
External Links
UniProt Q8B489
EMBL AY167440
ProteinModelPortal Q8B489
GO GO:0005524
GO:0004482
GO:0004483
GO:0003968
Gene3D 3.40.50.150
InterPro IPR026490
IPR000208
IPR002877
IPR029063
Pfam PF00972
PF01728
SUPFAM SSF53335
PROSITE PS51591

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0003968

RNA-directed RNA polymerase activity

PMID:21471248[1]

ECO:0000315

F

Fig. 5 shows RNA polymerase activity through mutations in the Dengue Fever virus.

complete
CACAO 4205

enables

GO:0003968

RNA-directed 5'-3' RNA polymerase activity

PMID:21471248[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0001172

transcription, RNA-templated

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0003968

P

Seeded From UniProt

complete

involved_in

GO:0001172

transcription, RNA-templated

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0003968

P

Seeded From UniProt

complete

involved_in

GO:0006370

7-methylguanosine mRNA capping

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0004482

P

Seeded From UniProt

complete

involved_in

GO:0080009

mRNA methylation

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0004483

P

Seeded From UniProt

complete

involved_in

GO:0106005

RNA 5'-cap (guanine-N7)-methylation

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0004482

P

Seeded From UniProt

complete

enables

GO:0003968

RNA-directed 5'-3' RNA polymerase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000208

F

Seeded From UniProt

complete

enables

GO:0004482

mRNA (guanine-N7-)-methyltransferase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR026490

F

Seeded From UniProt

complete

enables

GO:0004483

mRNA (nucleoside-2'-O-)-methyltransferase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR026490

F

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000208

F

Seeded From UniProt

complete

enables

GO:0008168

methyltransferase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002877

F

Seeded From UniProt

complete

involved_in

GO:0032259

methylation

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002877

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Iglesias, NG et al. (2011) The F1 motif of dengue virus polymerase NS5 is involved in promoter-dependent RNA synthesis. J. Virol. 85 5745-56 PubMed GONUTS page