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MEASZ:Q77M22

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Species (Taxon ID) Measles virus (strain Edmonston-Zagreb vaccine) (MeV) (Subacutesclerose panencephalitis virus). (70149)
Gene Name(s) L (ECO:0000313 with EMBL:AAF85698.1)
Protein Name(s) RNA-directed RNA polymerase L (ECO:0000256 with PIRNR:PIRNR000830)

Protein L (ECO:0000256 with PIRNR:PIRNR000830) Large structural protein (ECO:0000256 with PIRNR:PIRNR000830) Replicase (ECO:0000256 with PIRNR:PIRNR000830) Transcriptase (ECO:0000256 with PIRNR:PIRNR000830) RNA-directed RNA polymerase (ECO:0000256 with PIRNR:PIRNR000830) mRNA (guanine-N(7)-)-methyltransferase (ECO:0000256 with PIRNR:PIRNR000830) GDP polyribonucleotidyltransferase (ECO:0000256 with PIRNR:PIRNR000830) Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2 (ECO:0000256 with PIRNR:PIRNR000830)

External Links
UniProt Q77M22
EMBL AF266290
Proteomes UP000116098
GO GO:0030430
GO:0019012
GO:0005524
GO:0004482
GO:0003968
InterPro IPR024352
IPR039736
IPR026890
IPR014023
IPR025786
IPR016269
Pfam PF12803
PF14318
PF00946
PIRSF PIRSF000830
TIGRFAMs TIGR04198
PROSITE PS50526
PS51590

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0001172

transcription, RNA-templated

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0003968

P

Seeded From UniProt

involved_in

GO:0001172

transcription, RNA-templated

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0003968

P

Seeded From UniProt

involved_in

GO:0001172

transcription, RNA-templated

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0003968

P

Seeded From UniProt

involved_in

GO:0106005

RNA 5'-cap (guanine-N7)-methylation

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0004482

P

Seeded From UniProt

involved_in

GO:0106005

RNA 5'-cap (guanine-N7)-methylation

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0004482

P

Seeded From UniProt

enables

GO:0003968

RNA-directed 5'-3' RNA polymerase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR014023

F

Seeded From UniProt

enables

GO:0004482

mRNA (guanine-N7-)-methyltransferase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR014023

F

Seeded From UniProt

enables

GO:0005524

ATP binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR014023

F

Seeded From UniProt

involved_in

GO:0006139

nucleobase-containing compound metabolic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR016269

P

Seeded From UniProt

involved_in

GO:0006370

7-methylguanosine mRNA capping

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR014023

P

Seeded From UniProt

enables

GO:0016740

transferase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR016269

F

Seeded From UniProt

enables

GO:0003968

RNA-directed 5'-3' RNA polymerase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:2.7.7.48

F

Seeded From UniProt

enables

GO:0004482

mRNA (guanine-N7-)-methyltransferase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:2.1.1.56

F

Seeded From UniProt

enables

GO:0005524

ATP binding

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0067

F

Seeded From UniProt

enables

GO:0016779

nucleotidyltransferase activity

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0548

F

Seeded From UniProt

enables

GO:0008168

methyltransferase activity

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0489

F

Seeded From UniProt

enables

GO:0016740

transferase activity

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0808

F

Seeded From UniProt

part_of

GO:0019012

virion

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0946

C

Seeded From UniProt

involved_in

GO:0032259

methylation

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0489

P

Seeded From UniProt

involved_in

GO:0006370

7-methylguanosine mRNA capping

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0506

P

Seeded From UniProt

part_of

GO:0030430

host cell cytoplasm

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-1035

C

Seeded From UniProt

enables

GO:0003824

catalytic activity

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0511

F

Seeded From UniProt

involved_in

GO:0006397

mRNA processing

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0507

P

Seeded From UniProt

involved_in

GO:0008152

metabolic process

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0511

P

Seeded From UniProt

enables

GO:0000166

nucleotide binding

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0547

F

Seeded From UniProt

enables

GO:0003968

RNA-directed 5'-3' RNA polymerase activity

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0696

F

Seeded From UniProt

part_of

GO:0019012

virion

GO_REF:0000040

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-SubCell:SL-0274

C

Seeded From UniProt

part_of

GO:0030430

host cell cytoplasm

GO_REF:0000040

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-SubCell:SL-0381

C

Seeded From UniProt

involved_in

GO:0001172

transcription, RNA-templated

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0003968

P

Seeded From UniProt

involved_in

GO:0001172

transcription, RNA-templated

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0003968

P

Seeded From UniProt

involved_in

GO:0001172

transcription, RNA-templated

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0003968

P

Seeded From UniProt

involved_in

GO:0106005

RNA 5'-cap (guanine-N7)-methylation

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0004482

P

Seeded From UniProt

involved_in

GO:0106005

RNA 5'-cap (guanine-N7)-methylation

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0004482

P

Seeded From UniProt

enables

GO:0003968

RNA-directed 5'-3' RNA polymerase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR014023

F

Seeded From UniProt

enables

GO:0004482

mRNA (guanine-N7-)-methyltransferase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR014023

F

Seeded From UniProt

enables

GO:0005524

ATP binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR014023

F

Seeded From UniProt

involved_in

GO:0006139

nucleobase-containing compound metabolic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR016269

P

Seeded From UniProt

involved_in

GO:0006370

7-methylguanosine mRNA capping

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR014023

P

Seeded From UniProt

enables

GO:0016740

transferase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR016269

F

Seeded From UniProt

enables

GO:0003968

RNA-directed 5'-3' RNA polymerase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:2.7.7.48

F

Seeded From UniProt

enables

GO:0004482

mRNA (guanine-N7-)-methyltransferase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:2.1.1.56

F

Seeded From UniProt

enables

GO:0005524

ATP binding

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0067

F

Seeded From UniProt

enables

GO:0016779

nucleotidyltransferase activity

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0548

F

Seeded From UniProt

enables

GO:0008168

methyltransferase activity

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0489

F

Seeded From UniProt

enables

GO:0016740

transferase activity

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0808

F

Seeded From UniProt

part_of

GO:0019012

virion

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0946

C

Seeded From UniProt

involved_in

GO:0032259

methylation

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0489

P

Seeded From UniProt

involved_in

GO:0006370

7-methylguanosine mRNA capping

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0506

P

Seeded From UniProt

part_of

GO:0030430

host cell cytoplasm

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-1035

C

Seeded From UniProt

enables

GO:0003824

catalytic activity

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0511

F

Seeded From UniProt

involved_in

GO:0006397

mRNA processing

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0507

P

Seeded From UniProt

involved_in

GO:0008152

metabolic process

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0511

P

Seeded From UniProt

enables

GO:0000166

nucleotide binding

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0547

F

Seeded From UniProt

enables

GO:0003968

RNA-directed 5'-3' RNA polymerase activity

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0696

F

Seeded From UniProt

part_of

GO:0019012

virion

GO_REF:0000040

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-SubCell:SL-0274

C

Seeded From UniProt

part_of

GO:0030430

host cell cytoplasm

GO_REF:0000040

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-SubCell:SL-0381

C

Seeded From UniProt

GO:0019012

virion

PMID:30326905[1]

ECO:0005527

matrix-assisted laser desorption/ionization time-of-flight mass spectrometry evidence used in manual assertion

C

Figure 1 shows that protein L (RNA-directed RNA polymerase L) is a viral protein of the Measles virus as determined through MALDI-TOF/TOF-mass spectrometry. RNA-directed RNA polymerase L is displayed on an SDS-PAGE purified by UC after MALDI-TOF/TOF MS analysis. Table S1 includes proteins coded by MEV genome with the UniProt entry. UniProtKB - Q77M22 (Q77M22_MEASZ), RNA-directed RNA polymerase L Organism: Measles virus (strain Edmonston-Zagreb vaccine) (MeV) (Subacute sclerose panencephalitis virus)

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Sviben, D et al. (2018) Mass spectrometry-based investigation of measles and mumps virus proteome. Virol. J. 15 160 PubMed GONUTS page