9FLAV:G4XII4

Species (Taxon ID)	Tick-borne encephalitis virus. (11084)
Gene Name(s)	No Information Provided.
Protein Name(s)	Genome polyprotein (ECO:0000256 with SAAS:SAAS00058068)
External Links
UniProt	G4XII4
EMBL	JF819648
GO	GO:0033644 GO:0016021 GO:0019028 GO:0019031 GO:0005524 GO:0008026 GO:0003725 GO:0004482 GO:0004483 GO:0003724 GO:0003968 GO:0004252 GO:0070008 GO:0005198 GO:0039654 GO:0039694 GO:0019062
Gene3D	2.60.40.350 2.60.98.10 3.30.387.10 3.30.67.10 3.40.50.150 3.40.50.300
InterPro	IPR011492 IPR000069 IPR013755 IPR001122 IPR026470 IPR001157 IPR000752 IPR000487 IPR000404 IPR001528 IPR002535 IPR000336 IPR001850 IPR027287 IPR014412 IPR011998 IPR013756 IPR013754 IPR014001 IPR001650 IPR014756 IPR026490 IPR027417 IPR000208 IPR007094 IPR002877 IPR029063 IPR009003
Pfam	PF01003 PF07652 PF02832 PF00869 PF01004 PF00948 PF01005 PF01002 PF01350 PF01349 PF00972 PF01570 PF01728 PF00271 PF00949
PIRSF	PIRSF003817
SMART	SM00487 SM00490
SUPFAM	SSF50494 SSF52540 SSF53335 SSF56983 SSF81296
TIGRFAMs	TIGR04240
PROSITE	PS51527 PS51528 PS51192 PS51194 PS50507 PS51591

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Notes	Status
	GO:0019079	viral genome replication	PMID:22796133^[1]	ECO:0000315			P	Figure 2. Mutations is the NS5 protein in viral replication of Tick-borne encephalitis	complete CACAO 8674
	GO:0019079	viral genome replication	PMID:22796133^[1]	ECO:0000314			P	Figure 3.A. Contains SDS-PAGE of cytoplasmic fractions. The NS5 specific antibody revealed a band at the expected size of TBEVNS5 (103 kDa), but also an additional band around 70 kDa.	complete CACAO 8675
	GO:0019079	viral genome replication	PMID:22796133^[1]	ECO:0000314			P	Figure 3B.Binding capacities of NS5 of Tick-borne encephalitis and West Nile virus encephalitis.	complete CACAO 8676
involved_in	GO:0019079	viral genome replication	PMID:22796133^[1]	ECO:0000314	direct assay evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0019079	viral genome replication	PMID:22796133^[1]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0001172	transcription, RNA-templated	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0003968	P	Seeded From UniProt	complete
involved_in	GO:0001172	transcription, RNA-templated	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0003968	P	Seeded From UniProt	complete
involved_in	GO:0001172	transcription, RNA-templated	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0003968	P	Seeded From UniProt	complete
involved_in	GO:0006508	proteolysis	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0004252	P	Seeded From UniProt	complete
involved_in	GO:0080009	mRNA methylation	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0004483	P	Seeded From UniProt	complete
involved_in	GO:0106005	RNA 5'-cap (guanine-N7)-methylation	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0004482	P	Seeded From UniProt	complete
enables	GO:0003723	RNA binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001850	F	Seeded From UniProt	complete
enables	GO:0003724	RNA helicase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001850	F	Seeded From UniProt	complete
enables	GO:0003725	double-stranded RNA binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000752	F	Seeded From UniProt	complete
enables	GO:0003968	RNA-directed 5'-3' RNA polymerase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000208 InterPro:IPR007094 InterPro:IPR014412	F	Seeded From UniProt	complete
enables	GO:0004252	serine-type endopeptidase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000487 InterPro:IPR014412	F	Seeded From UniProt	complete
enables	GO:0004482	mRNA (guanine-N7-)-methyltransferase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR014412 InterPro:IPR026490	F	Seeded From UniProt	complete
enables	GO:0004483	mRNA (nucleoside-2'-O-)-methyltransferase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR014412 InterPro:IPR026490	F	Seeded From UniProt	complete
enables	GO:0005198	structural molecule activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001122	F	Seeded From UniProt	complete
enables	GO:0005524	ATP binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000208 InterPro:IPR001850 InterPro:IPR011492	F	Seeded From UniProt	complete
enables	GO:0008026	ATP-dependent helicase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR011492	F	Seeded From UniProt	complete
enables	GO:0008168	methyltransferase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR002877	F	Seeded From UniProt	complete
involved_in	GO:0016032	viral process	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000404	P	Seeded From UniProt	complete
involved_in	GO:0016070	RNA metabolic process	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000404	P	Seeded From UniProt	complete
enables	GO:0016817	hydrolase activity, acting on acid anhydrides	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR014412	F	Seeded From UniProt	complete
enables	GO:0017111	nucleoside-triphosphatase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR014412	F	Seeded From UniProt	complete
part_of	GO:0019012	virion	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000404 InterPro:IPR000487	C	Seeded From UniProt	complete
part_of	GO:0019028	viral capsid	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001122	C	Seeded From UniProt	complete
part_of	GO:0019031	viral envelope	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000069	C	Seeded From UniProt	complete
involved_in	GO:0019058	viral life cycle	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000069	P	Seeded From UniProt	complete
involved_in	GO:0032259	methylation	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR002877	P	Seeded From UniProt	complete
involved_in	GO:0039694	viral RNA genome replication	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR007094	P	Seeded From UniProt	complete
enables	GO:0046983	protein dimerization activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR011998	F	Seeded From UniProt	complete
enables	GO:0003968	RNA-directed 5'-3' RNA polymerase activity	GO_REF:0000003	ECO:0000501	evidence used in automatic assertion	EC:2.7.7.48	F	Seeded From UniProt	complete
enables	GO:0017111	nucleoside-triphosphatase activity	GO_REF:0000003	ECO:0000501	evidence used in automatic assertion	EC:3.6.1.15	F	Seeded From UniProt	complete
part_of	GO:0019012	virion	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0946	C	Seeded From UniProt	complete
involved_in	GO:0046718	viral entry into host cell	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-1162	P	Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0472	C	Seeded From UniProt	complete
enables	GO:0000166	nucleotide binding	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0547	F	Seeded From UniProt	complete
enables	GO:0004386	helicase activity	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0347	F	Seeded From UniProt	complete
involved_in	GO:0039654	fusion of virus membrane with host endosome membrane	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-1170	P	Seeded From UniProt	complete
enables	GO:0008168	methyltransferase activity	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0489	F	Seeded From UniProt	complete
part_of	GO:0019028	viral capsid	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0167	C	Seeded From UniProt	complete
involved_in	GO:0039663	membrane fusion involved in viral entry into host cell	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-1168	P	Seeded From UniProt	complete
enables	GO:0046872	metal ion binding	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0479	F	Seeded From UniProt	complete
involved_in	GO:0016032	viral process	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0945	P	Seeded From UniProt	complete
involved_in	GO:0039503	suppression by virus of host innate immune response	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-1090	P	Seeded From UniProt	complete
enables	GO:0003723	RNA binding	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0694	F	Seeded From UniProt	complete
involved_in	GO:0006397	mRNA processing	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0507	P	Seeded From UniProt	complete
part_of	GO:0033644	host cell membrane	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-1043	C	Seeded From UniProt	complete
enables	GO:0003968	RNA-directed 5'-3' RNA polymerase activity	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0696	F	Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0812	C	Seeded From UniProt	complete
enables	GO:0016740	transferase activity	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0808	F	Seeded From UniProt	complete
part_of	GO:0030430	host cell cytoplasm	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-1035	C	Seeded From UniProt	complete
enables	GO:0016787	hydrolase activity	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0378	F	Seeded From UniProt	complete
involved_in	GO:0032259	methylation	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0489	P	Seeded From UniProt	complete
involved_in	GO:0046718	viral entry into host cell	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-1160	P	Seeded From UniProt	complete
enables	GO:0005524	ATP binding	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0067	F	Seeded From UniProt	complete
involved_in	GO:0039520	induction by virus of host autophagy	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-1072	P	Seeded From UniProt	complete
enables	GO:0016779	nucleotidyltransferase activity	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0548	F	Seeded From UniProt	complete
involved_in	GO:0019062	virion attachment to host cell	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-1161	P	Seeded From UniProt	complete
involved_in	GO:0006370	7-methylguanosine mRNA capping	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0506	P	Seeded From UniProt	complete
part_of	GO:0030430	host cell cytoplasm	GO_REF:0000040	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-SubCell:SL-0381	C	Seeded From UniProt	complete
part_of	GO:0044165	host cell endoplasmic reticulum	GO_REF:0000040	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-SubCell:SL-0388	C	Seeded From UniProt	complete
part_of	GO:0055036	virion membrane	GO_REF:0000040	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-SubCell:SL-0275	C	Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 ^1.2 ^1.3 ^1.4 Melik, W et al. (2012) Two PDZ binding motifs within NS5 have roles in Tick-borne encephalitis virus replication. Virus Res. 169 54-62 PubMed GONUTS page

[PMID:22796133-1] 1.0 ^1.1 ^1.2 ^1.3 ^1.4 Melik, W et al. (2012) Two PDZ binding motifs within NS5 have roles in Tick-borne encephalitis virus replication. Virus Res. 169 54-62 PubMed GONUTS page

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9FLAV:G4XII4

Contents

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Notes

References

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