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I33A0:PB2
Contents
| Species (Taxon ID) | Influenza A virus (strain A/Wilson-Smith/1933 H1N1) (Influenza A virus(strain A/WS/1933 H1N1)). (381518) | |
| Gene Name(s) | PB2 | |
| Protein Name(s) | Polymerase basic protein 2
RNA-directed RNA polymerase subunit P3 | |
| External Links | ||
| UniProt | P03427 | |
| EMBL | J02179 | |
| ProteinModelPortal | P03427 | |
| SMR | P03427 | |
| IntAct | P03427 | |
| MINT | MINT-8081619 | |
| Proteomes | UP000000834 | |
| GO | GO:0033650 GO:0042025 GO:0019012 GO:0003723 GO:0003968 GO:0006370 GO:0075526 GO:0039545 GO:0039523 GO:0006351 | |
| InterPro | IPR001591 | |
| Pfam | PF00604 | |
| ProDom | PD001667 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0033650 |
host cell mitochondrion |
ECO:0000314 |
C |
Seen in figure 4, PB2 is imported into the mitochondrial matrix of the host. Polymerase basic protein 2 Influenza A virus (strain A/Wilson-Smith/1933 H1N1) (Influenza A virus (strain A/WS/1933 H1N1)) |
complete | |||||
|
involved_in |
GO:0039689 |
negative stranded viral RNA replication |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0042025 |
host cell nucleus |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0001172 |
transcription, RNA-templated |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0003968 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0003723 |
RNA binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006351 |
transcription, DNA-templated |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0039694 |
viral RNA genome replication |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003723 |
RNA binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000523929 |
F |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0042025 |
host cell nucleus |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000523929 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0019012 |
virion |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000523929 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0033650 |
host cell mitochondrion |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000523929 |
C |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0075526 |
cap snatching |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000523929 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006370 |
7-methylguanosine mRNA capping |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000523929 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0039523 |
suppression by virus of host RNA polymerase II activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000523929 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0003968 |
RNA-directed 5'-3' RNA polymerase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000523929 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006351 |
transcription, DNA-templated |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000523929 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0019083 |
viral transcription |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000523929 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0039545 |
suppression by virus of host MAVS activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000523929 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0042025 |
host cell nucleus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006370 |
7-methylguanosine mRNA capping |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0033650 |
host cell mitochondrion |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0039657 |
suppression by virus of host gene expression |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0030683 |
evasion or tolerance by virus of host immune response |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006397 |
mRNA processing |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0019083 |
viral transcription |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0075526 |
cap snatching |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0039545 |
suppression by virus of host MAVS activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0016032 |
viral process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0039523 |
suppression by virus of host RNA polymerase II activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0039503 |
suppression by virus of host innate immune response |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0019012 |
virion |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Long, JC & Fodor, E (2016) The PB2 Subunit of the Influenza A Virus RNA Polymerase Is Imported into the Mitochondrial Matrix. J. Virol. 90 8729-38 PubMed GONUTS page
- ↑ Huang, TS et al. (1990) Determination of influenza virus proteins required for genome replication. J. Virol. 64 5669-73 PubMed GONUTS page
- ↑ Mukaigawa, J & Nayak, DP (1991) Two signals mediate nuclear localization of influenza virus (A/WSN/33) polymerase basic protein 2. J. Virol. 65 245-53 PubMed GONUTS page
r
s
- ssRNA negative-strand viruses
- GO:0039523 ! symbiont-mediated suppression of host mRNA transcription via inhibition of RNA polymerase II activity
- GO:0039545 ! symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity
- GO:0039657 ! symbiont-mediated suppression of host gene expression
